Highly fluorescent hyperbranched BODIPY-based conjugated polymer dots for cellular imaging

2017 ◽  
Vol 53 (61) ◽  
pp. 8612-8615 ◽  
Author(s):  
Rongxin Du ◽  
Shuang Cui ◽  
Zezhou Sun ◽  
Ming Liu ◽  
Yong Zhang ◽  
...  
Keyword(s):  
Conjugated Polymers ◽  
Conjugated Polymer ◽  
Cellular Imaging ◽  
Feeding Method ◽  
Polymer Dots

Highly fluorescent hyperbranched conjugated polymers were prepared using a portion feeding method and successfully applied in biological in vitro and in vivo applications.

Simultaneous near-infrared and green fluorescence from single conjugated polymer dots with aggregation-induced emission fluorogen for cell imaging

2018 ◽  
Vol 6 (47) ◽  
pp. 7871-7876 ◽  
Author(s):  
Sitong Chen ◽  
Shuang Cui ◽  
Rongxin Du ◽  
Ming Liu ◽  
Wei-Kai Tsai ◽  
...  
Keyword(s):  
Conjugated Polymer ◽  
Near Infrared ◽  
Cell Imaging ◽  
Green Fluorescence ◽  
Aggregation Induced Emission ◽  
Polymer Dots

Highly fluorescent conjugated polymer dots with aggregation-induced emission fluorogen were applied in in vitro and in vivo cell imaging.

NIR‐II Excitable Conjugated Polymer Dots with Bright NIR‐I Emission for Deep In Vivo Two‐Photon Brain Imaging Through Intact Skull

2019 ◽  
Vol 29 (15) ◽  
pp. 1808365 ◽  
Author(s):  
Shaowei Wang ◽  
Jie Liu ◽  
Guangxue Feng ◽  
Lai Guan Ng ◽  
Bin Liu
Keyword(s):  
Brain Imaging ◽  
Conjugated Polymer ◽  
Two Photon ◽  
Polymer Dots

Enhanced In Vitro and In Vivo Cellular Imaging with Green Tea Coated Water-Soluble Iron Oxide Nanocrystals

2015 ◽  
Vol 7 (12) ◽  
pp. 6530-6540 ◽  
Author(s):  
Lisong Xiao ◽  
Marianne Mertens ◽  
Laura Wortmann ◽  
Silke Kremer ◽  
Martin Valldor ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Green Tea ◽  
Cellular Imaging ◽  
Water Soluble ◽  
Soluble Iron

scholarly journals Impact of sterilization on a conjugated polymer based bioelectronic patch

2021 ◽  
Author(s):  
Yihan Yan ◽  
Lorenzo Travaglini ◽  
Kieran Lau ◽  
Jelena Rnjak-Kovacina ◽  
Minoo Eslami ◽  
...  
Keyword(s):  
Ethylene Oxide ◽  
Conjugated Polymers ◽  
Electronic Properties ◽  
Conjugated Polymer ◽  
Active Material ◽  
High Dose ◽  
Γ Irradiation ◽  
The Impact

ABSTRACTTranslation into the clinic of organic bioelectronic devices having conjugated polymers as the active material will hinge on their long-term operation in vivo. This will require the device to be subject to clinically approved sterilization techniques without a deterioration in its physical and electronic properties. To date, there remains a gap in the literature addressing the impact of this critical pre-operative procedure on the properties of conjugated polymers. This study aims to address this gap by assessing the physical and electronic properties of a sterilized porous bioelectronic patch having polyaniline as the conjugated polymer. The patch was sterilized by autoclave, ethylene oxide and gamma (γ-) irradiation at 15, 25, and 50 kGy doses. Autoclaving resulted in cracking and macroscopic degradation of the patch, while patches sterilized by γ-irradiation at 50 kGy exhibited reduced mechanical and electronic properties, attributed to chain scission and non-uniform crosslinking caused by the high dose irradiation. Ethylene oxide and γ-irradiation at 15 and 25 kGy sterilization appeared to be the most effective at maintaining the mechanical and electronic properties of the patch, as well as inducing a minimal immune response as revealed by a receding fibrotic capsule after 4 weeks implantation. Our findings pave the way towards closing the gap for the translation of organic bioelectronic devices from acute to long-term in vivo models.

scholarly journals Tunable luminescence from two dimensional BCNO nanophosphor for high-contrast cellular imaging

RSC Advances ◽  
2017 ◽  
Vol 7 (66) ◽  
pp. 41486-41494 ◽  
Author(s):  
Bipin Kumar Gupta ◽  
Pawan Kumar ◽  
Garima Kedawat ◽  
Kanika Kanika ◽  
Sajna Antony Vithayathil ◽  
...  
Keyword(s):  
Rare Earth ◽  
Paradigm Shift ◽  
Cellular Imaging ◽  
Two Dimensional ◽  
High Contrast

Multi-colour emitting nanophosphors provide a paradigm shift in rare-earth free biocompatible nanoprobes for in vitro and in vivo imaging applications.

Trichromatic-emission and dual-ratio semiconducting polymer dots as fluorescent probe for simultaneous quantification of Cu2+ and pH in vitro and in vivo

2020 ◽  
Vol 56 (61) ◽  
pp. 8647-8650
Author(s):  
Qiang Zhang ◽  
Junyong Sun ◽  
Rongchao Zhang ◽  
Xueli Chen ◽  
Ningning Chen ◽  
...  
Keyword(s):  
Hela Cells ◽  
Simultaneous Detection ◽  
Blue Color ◽  
Semiconducting Polymer ◽  
Simultaneous Quantification ◽  
Polymer Dots ◽  
Multicolor Imaging ◽  
Semiconducting Polymer Dots

Polymer dots emitting in the red, green and blue color regions, have been successfully applied as lysosome-targeting nanoprobes for the simultaneous detection and multicolor imaging of pH and Cu2+ in HeLa cells and zebrafish.

A Porphyrin-Based Conjugated Polymer for Highly Efficient In Vitro and In Vivo Photothermal Therapy

Small ◽  
2016 ◽  
Vol 12 (45) ◽  
pp. 6243-6254 ◽  
Author(s):  
Bing Guo ◽  
Guangxue Feng ◽  
Purnima Naresh Manghnani ◽  
Xiaolei Cai ◽  
Jie Liu ◽  
...  
Keyword(s):  
Conjugated Polymer ◽  
Photothermal Therapy ◽  
Highly Efficient

AIE-active conjugated polymer nanoparticles with red-emission for in vitro and in vivo imaging

RSC Advances ◽  
2016 ◽  
Vol 6 (115) ◽  
pp. 114580-114586 ◽  
Author(s):  
Dongliang Yang ◽  
Shuwei Zhang ◽  
Yanling Hu ◽  
Jia Chen ◽  
Biqing Bao ◽  
...  
Keyword(s):  
In Vivo Imaging ◽  
Conjugated Polymer ◽  
Fluorescence Emission ◽  
Polymer Nanoparticles ◽  
Red Emission ◽  
Bright Fluorescence ◽  
Conjugated Polymer Nanoparticles ◽  
Excellent Photostability

Novel AIE-active conjugated polymer nanoparticles with bright fluorescence emission and excellent photostability have been prepared for imaging in cells and zebrafish.

scholarly journals Fluorescence Modulation of Conjugated Polymer Nanoparticles Embedded in Poly(N-Isopropylacrylamide) Hydrogel

Polymers ◽  
2021 ◽  
Vol 13 (24) ◽  
pp. 4315
Author(s):  
Ho Namgung ◽  
Seonyoung Jo ◽  
Taek Seung Lee
Keyword(s):  
Conjugated Polymers ◽  
Conjugated Polymer ◽  
Excitation Wavelength ◽  
Visible Absorption ◽  
Polymer Hydrogel ◽  
Polymer Dots ◽  
Phenylene Group ◽  
Conjugated Polymer Nanoparticles ◽  
Fluorescence Modulation ◽  
Reprecipitation Method

A series of conjugated polymers (CPs) emitting red, green, and blue (RGB) fluorescence were synthesized via the Suzuki coupling polymerization. Polymer dots (Pdots) were fabricated by the reprecipitation method from corresponding CPs, in which the Pdot surface was functionalized to have an allyl moiety. The CP backbones were based on the phenylene group, causing the Pdots to show identical ultraviolet-visible absorption at 350 nm, indicating that the same excitation wavelength could be used. The Pdots were covalently embedded in poly(N-isopropylacrylamide) (PNIPAM) hydrogel for further use as a thermoresponsive moiety in the polymer hydrogel. The polymer hydrogel with RGB emission colors could provide thermally reversible fluorescence changes. The size of the hydrogel varied with temperature change because of the PNIPAM’s shrinking and swelling. The swollen and contracted conformations of the Pdot-embedded PNIPAM enabled on-and-off fluorescence, respectively. Fluorescence modulation with 20 to 80% of the hydrogel was possible via thermoreversibility. The fluorescent hydrogel could be a new fluorescence-tuning hybrid material that changes with temperature.

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