NO prodrug-conjugated, self-assembled, pH-responsive and galactose receptor targeted nanoparticles for co-delivery of nitric oxide and doxorubicin

Nanoscale ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 4179-4188 ◽  
Author(s):  
Jimin Zhang ◽  
Huijuan Song ◽  
Shenglu Ji ◽  
Xiaomin Wang ◽  
Pingsheng Huang ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Ph Responsive ◽  
Targeted Nanoparticles ◽  
Self Assembled

Nitric oxide (NO) prodrug-conjugated, acid-responsive and galactose receptor targeted nanoparticles were developed for the co-delivery of NO and doxorubicin.

Simple Formation of Cancer Drug-Containing Self-Assembled Hydrogels with Temperature and pH-Responsive Release

Langmuir ◽  
2021 ◽  
Vol 37 (38) ◽  
pp. 11269-11275
Author(s):  
Ji Ha Lee ◽  
Tomoyuki Tachibana ◽  
Keita Yamana ◽  
Riku Kawasaki ◽  
Akihiro Yabuki
Keyword(s):  
Cancer Drug ◽  
Ph Responsive ◽  
Self Assembled

Interaction of nitric oxide with Ru(II) complexes of deuteroporphyrindimethylester derivatives

2009 ◽  
Vol 13 (01) ◽  
pp. 35-40 ◽  
Author(s):  
Rudy Martin ◽  
Roberto Cao ◽  
Ana M. Esteva ◽  
Franz-Peter Montforts
Keyword(s):  
Nitric Oxide ◽  
Photoelectron Spectroscopy ◽  
Gold Electrode ◽  
Charge Transfer Band ◽  
Bathochromic Shift ◽  
Considerable Change ◽  
Cathodic Peak ◽  
X Ray ◽  
Polycrystalline Gold ◽  
Self Assembled

A new ruthenium(II) porphyrin disulphide derivative, [ Ru ( Pds )( CO )], was obtained from ruthenium(II)(carbonyl)deuteroporphyrin(IX), [ Ru ( DPdc )( CO )] and cystamine. The interaction of this complex with nitric oxide was studied spectrophotometrically and a bathochromic shift of the charge transfer band and considerable change in the α and β bands of the complex were observed. According to the IR spectrum, the product of this interaction is [ Ru ( DmDP )( NO +)( NO 2-)]. [ Ru ( Pds )( CO )] was then self-assembled on polycrystalline gold and characterized by X-ray photoelectron spectroscopy. [ Ru ( Pds )( CO )] was also self-assembled on gold electrode beads and its interaction with nitric oxide in aqueous solution was studied by cyclic voltammetry. A shift in the ruthenium redox process and a new irreversible cathodic peak at -0.59 V were observed, both indicating coordination of NO .

Novel self-assembled pH-responsive biomimetic nanocarriers for drug delivery

2016 ◽  
Vol 64 ◽  
pp. 346-353 ◽  
Author(s):  
Minming Wu ◽  
Zhaoyu Cao ◽  
Yunfei Zhao ◽  
Rong Zeng ◽  
Mei Tu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Ph Responsive ◽  
Self Assembled

De novo synthesis of pH-responsive, self-assembled, and targeted polypeptide nano-micelles for enhanced delivery of doxorubicin

2021 ◽  
Author(s):  
Longbao Zhu ◽  
Wen-liang Xu ◽  
Weiwei Zhang ◽  
Ming-cai Wu ◽  
Wanzhen Li ◽  
...  
Keyword(s):  
De Novo ◽  
Ph Responsive ◽  
De Novo Synthesis ◽  
Self Assembled

pH-Responsive de-PEGylated nanoparticles based on triphenylphosphine–quercetin self-assemblies for mitochondria-targeted cancer therapy

2017 ◽  
Vol 53 (62) ◽  
pp. 8790-8793 ◽  
Author(s):  
Lei Xing ◽  
Jin-Yuan Lyu ◽  
Yue Yang ◽  
Peng-Fei Cui ◽  
Liu-Qing Gu ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Coordination Bond ◽  
The Self ◽  
Targeted Cancer Therapy ◽  
Ph Responsive ◽  
Pegylated Nanoparticles ◽  
Self Assembled

The self-assembled nanosystem formulated with amphiphilic TPP–Que and PBA–PEG through a coordination bond could balance the dilemma of PEGylation.

scholarly journals Self-Assembled Metal-Phenolic Networks on Emulsions as Low-Fouling and pH-Responsive Particles

Small ◽  
2018 ◽  
Vol 14 (39) ◽  
pp. 1802342 ◽  
Author(s):  
Quinn A. Besford ◽  
Yi Ju ◽  
Ting-Yi Wang ◽  
Gyeongwon Yun ◽  
PavelV. Cherepanov ◽  
...  
Keyword(s):  
Ph Responsive ◽  
Self Assembled

Ionically Self-Assembled Monolayer pH Sensitive Films-Fabrication and their Long Term Response to Varying Temperature Conditions

2021 ◽  
Vol 878 ◽  
pp. 15-22
Author(s):  
Brianna A. Richmond ◽  
Carisa D. Kunkle ◽  
Daniela M. Topasna
Keyword(s):  
Room Temperature ◽  
Ph Responsive ◽  
Self Assembled Monolayer ◽  
Percent Change ◽  
Temperature Conditions ◽  
Glass Slides ◽  
Long Time ◽  
Self Assembled ◽  
Term Response

This study presents the long time effects of varying temperature conditions on pH-responsive films deposited on glass slides. The films were fabricated from Brilliant Yellow and poly (allylamine hydrochloride) through ionically self-assembled monolayer technique using an automated slide strainer. The absorbance of the films was monitored and the effect of varying temperature on the optical properties of the films was studied. We found that as the films are maintained at increasing temperatures their absorbance slightly decreased. As the temperature increased the percent change decreased reaching a plateau. Films kept at low temperatures of 3.24 °C and below freezing (-9.02 °C) had a small increase in absorbance. Finally, we monitored the absorbance of films kept at room temperature over a long time (128 days) and found that the films showed decreased absorbance by 19%.

pH-responsive polymeric micelles self-assembled from benzoic-imine-containing alkyl-modified PEGylated chitosan for delivery of amphiphilic drugs

2020 ◽  
Vol 163 ◽  
pp. 1106-1116
Author(s):  
Ching-Wei Hsu ◽  
Ming-Hung Hsieh ◽  
Min-Cong Xiao ◽  
Ya-Hsuan Chou ◽  
Tzu-Hao Wang ◽  
...  
Keyword(s):  
Polymeric Micelles ◽  
Ph Responsive ◽  
Amphiphilic Drugs ◽  
Self Assembled
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