scholarly journals Endogenous omega-3 long-chain fatty acid biosynthesis from alpha-linolenic acid is affected by substrate levels, gene expression, and product inhibition

RSC Advances ◽  
2017 ◽  
Vol 7 (65) ◽  
pp. 40946-40951 ◽  
Author(s):  
Shun-he Wang ◽  
Yong Pan ◽  
Jing Li ◽  
Hai-qin Chen ◽  
Hao Zhang ◽  
...  

Previous studies have suggested that dietary alpha-linolenic acid (ALA) increases the levels of omega-3 long-chain polyunsaturated fatty acids (ω-3 LC-PUFAs)in vivo, but the conversion procedure and the genes involved remain poorly understood.

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