Metal-free oxidative coupling of quinoxalin-2(1H)-ones with arylaldehydes leading to 3-acylated quinoxalin-2(1H)-ones

2018 ◽  
Vol 16 (17) ◽  
pp. 3203-3212 ◽  
Author(s):  
Jin-Wei Yuan ◽  
Jun-Hao Fu ◽  
Shuai-Nan Liu ◽  
Yong-Mei Xiao ◽  
Pu Mao ◽  
...  
Keyword(s):  
Oxidative Coupling ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Metal Free ◽  
Aryl Aldehydes ◽  
Mild Conditions ◽  
Cross Coupling Reaction

An efficient protocol for the synthesis of 3-aroylquinoxalin-2(1H)-ones has been developed via a metal-free oxidative cross-coupling reaction of quinoxalin-2(1H)-ones with aryl aldehydes under mild conditions with good yields.

Direct C-4 alkylation of quinazoline N-oxides with ethers via an oxidative cross-coupling reaction under metal-free conditions

2018 ◽  
Vol 16 (45) ◽  
pp. 8724-8731 ◽  
Author(s):  
Qin Yang ◽  
Minhao Lou ◽  
Zhijian Yin ◽  
Zhihong Deng ◽  
Qiuping Ding ◽  
...  
Keyword(s):  
Oxidative Coupling ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Metal Free ◽  
Cross Coupling Reaction

A novel and efficient protocol for the direct C-4 alkylation of quinazoline-3-oxides via radical oxidative coupling between quinazoline 3-oxides and ethers in the presence of TBHP is presented.

Transition-metal-free direct C-3 alkylation of quinoxalin-2(1H)-ones with ethers

2018 ◽  
Vol 5 (19) ◽  
pp. 2820-2828 ◽  
Author(s):  
Jinwei Yuan ◽  
Junhao Fu ◽  
Jihong Yin ◽  
Zhenhua Dong ◽  
Yongmei Xiao ◽  
...  
Keyword(s):  
Transition Metal ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Metal Free ◽  
Mild Conditions ◽  
Cross Coupling Reaction

An efficient protocol for the synthesis of 3-alkyl quinoxalin-2(1H)-ones has been developed via the transition-metal-free cross-coupling reaction of quinoxalin-2(1H)-ones with ethers with moderate to good yields under relatively mild conditions.

ChemInform Abstract: A Transition-Metal-Free Cross-Coupling Reaction of Allylic Bromides with Aryl- and Vinylboronic Acids.

ChemInform ◽  
2012 ◽  
Vol 43 (33) ◽  
pp. no-no
Author(s):  
Mitsuhiro Ueda ◽  
Kota Nishimura ◽  
Ryo Kashima ◽  
Ilhyong Ryu
Keyword(s):  
Transition Metal ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Metal Free ◽  
Cross Coupling Reaction

scholarly journals A New Heterogeneous Catalyst Obtained via Supramolecular Decoration of Graphene with a Pd2+ Azamacrocyclic Complex

Molecules ◽  
2019 ◽  
Vol 24 (15) ◽  
pp. 2714 ◽  
Author(s):  
Matteo Savastano ◽  
Paloma Arranz-Mascarós ◽  
Maria Paz Clares ◽  
Rafael Cuesta ◽  
Maria Luz Godino-Salido ◽  
...  
Keyword(s):  
Heterogeneous Catalyst ◽  
Self Assembly ◽  
Room Temperature ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Assembly Process ◽  
Efficient Catalyst ◽  
Mild Conditions ◽  
Cross Coupling Reaction ◽  
Green Procedure

A new G-(H2L)-Pd heterogeneous catalyst has been prepared via a self-assembly process consisting in the spontaneous adsorption, in water at room temperature, of a macrocyclic H2L ligand on graphene (G) (G + H2L = G-(H2L)), followed by decoration of the macrocycle with Pd2+ ions (G-(H2L) + Pd2+ = G-(H2L)-Pd) under the same mild conditions. This supramolecular approach is a sustainable (green) procedure that preserves the special characteristics of graphene and furnishes an efficient catalyst for the Cu-free Sonogashira cross coupling reaction between iodobenzene and phenylacetylene. Indeed, G-(H2L)-Pd shows an excellent conversion (90%) of reactants into diphenylacetylene under mild conditions (50 °C, water, aerobic atmosphere, 14 h). The catalyst proved to be reusable for at least four cycles, although decreasing yields down to 50% were observed.

scholarly journals Pd(CH3CN)2Cl2/Pipecolinic Acid as a Highly Efficient Catalytic System for Suzuki-Miyaura Cross-coupling Reaction of Bromoaryl Carboxylic Acids in Water

Catalysts ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 86 ◽  
Author(s):  
Xiaogang Li ◽  
Wenbin Zhang ◽  
Leiqing Fu ◽  
Mengping Guo
Keyword(s):  
Catalytic System ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Catalytic Performance ◽  
High Turnover ◽  
Mild Conditions ◽  
Highly Efficient ◽  
Cross Coupling Reaction ◽  
Pipecolinic Acid ◽  
Excellent Catalytic Performance

In this study, a convenient and highly efficient catalytic system for the Suzuki-Miyaura coupling reaction was investigated under mild conditions. A combination of Pd(CH3CN)2Cl2 and pipecolinic acid showed excellent catalytic performance and afforded high turnover numbers; turnover numbers were up to 4.9 × 105 for the coupling reaction of 4-bromobenzoic acid and tetraphenylboron sodium. The catalytic system was also effective for the indexes of 4-bromobenzoic acid, and high turnover numbers were obtained.

Pd/APN-Mn(BTC) as novel, highly efficient, and recyclable catalyst for Suzuki–Miyaura cross coupling reaction

2020 ◽  
Vol 98 (8) ◽  
pp. 445-452
Author(s):  
Hamid Aliyan ◽  
Razieh Fazaeli
Keyword(s):  
Palladium Nanoparticles ◽  
Metal Organic Framework ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Analytical Techniques ◽  
Mild Conditions ◽  
Cross Coupling Reaction ◽  
Highly Dispersed ◽  
Metal Organic ◽  
Adsorption Desorption

A novel, heterogeneous, and bifunctional metal organic framework containing palladium and manganese, Pd/APN-Mn(BTC), has been prepared and completely characterized using FTIR, XRD, SEM-EDS, N2 adsorption–desorption, TG-DTG, NH3-TPD, and ICP analytical techniques. The APN-Mn(BTC) framework has been shown to be a useful platform for the stabilization and support of palladium nanoparticles (Pd NPs). Very effective catalytic activity has been exhibited by the highly dispersed Pd particles, Pd-NPs/APN-Mn(BTC), in the Suzuki–Miyaura cross-coupling reaction with reasonable to excellent reaction yields under mild conditions in H2O–ethanol solvent.

ChemInform Abstract: Selective Synthesis of Partially Protected Nonsymmetric Biphenols by Reagent- and Metal-Free Anodic Cross-Coupling Reaction.

ChemInform ◽  
2016 ◽  
Vol 47 (52) ◽  
Author(s):  
Anton Wiebe ◽  
Dieter Schollmeyer ◽  
Katrin M. Dyballa ◽  
Robert Franke ◽  
Siegfried R. Waldvogel
Keyword(s):  
Coupling Reaction ◽  
Cross Coupling ◽  
Selective Synthesis ◽  
Metal Free ◽  
Cross Coupling Reaction

Selective remote esterification of 8-aminoquinoline amides via copper(ii)-catalyzed C(sp2)–O cross-coupling reaction

2017 ◽  
Vol 15 (3) ◽  
pp. 531-535 ◽  
Author(s):  
Chengcai Xia ◽  
Kai Wang ◽  
Jun Xu ◽  
Chao Shen ◽  
Di Sun ◽  
...  
Keyword(s):  
Copper Catalyst ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Mild Conditions ◽  
Cross Coupling Reaction

The remote C–O coupling of quinoline amides at the C5 position has been established using cheap and readily available copper catalyst under mild conditions.

Transition metal-free tandem pyridinyl–allyl–allyl cross-coupling reaction

2017 ◽  
Vol 47 (18) ◽  
pp. 1668-1675 ◽  
Author(s):  
Lili Zhang ◽  
Zhengkai Chen ◽  
Hongli Li ◽  
Wenguang Yin ◽  
Jianfeng Xu ◽  
...  
Keyword(s):  
Transition Metal ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Metal Free ◽  
Cross Coupling Reaction
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