Cyclocondensation reactions of an electron deactivated 2-aminophenyl tethered imidazole with mono/1,2-biselectrophiles: synthesis and DFT studies on the rationalisation of imidazo[1,2-a]quinoxaline versus benzo[f]imidazo[1,5-a][1,3,5]triazepine selectivity switches

2018 ◽  
Vol 5 (24) ◽  
pp. 3526-3533 ◽  
Author(s):  
Gaurav Joshi ◽  
Monika Chauhan ◽  
Rakesh Kumar ◽  
Ankush Thakur ◽  
Sachin Sharma ◽  
...  
Keyword(s):  
Dft Studies ◽  
Microwave Assisted ◽  
High Yields ◽  
Cyclocondensation Reactions

Microwave-assisted cyclocondensation of title compounds afforded unreported imidazo[1,2-a] quinoxaline and benzo[f]imidazo[1,5-a][1,3,5]triazepines in high yields.

Solid-state regioselective nitration of activated hydroxyaromatics and hydroxycoumarins with cerium (IV) ammonium nitrate

2005 ◽  
Vol 2005 (11) ◽  
pp. 733-735 ◽  
Author(s):  
Nemai C. Ganguly ◽  
Sanjoy Dutta ◽  
Mrityunjoy Datta ◽  
Prithwiraj De
Keyword(s):  
Solid State ◽  
Ammonium Nitrate ◽  
High Efficiency ◽  
Solvent Free ◽  
High Melting ◽  
Microwave Assisted ◽  
Solvent Free Conditions ◽  
High Yields ◽  
Regioselective Nitration ◽  
Cerium Iv Ammonium Nitrate

Predominant ortho-selective mononitration of low-melting and liquid phenols and hydroxycoumarins in moderate to high yields has been accomplished upon grinding with solid cerium (IV) ammonium nitrate (CAN). Microwave-assisted expeditious CAN-mediated nitration of relatively high melting phenols and hydroxycoumarins with high efficiency and selectively under solvent-free conditions has been also developed to address the problems of sluggishness and low yield for these reluctant substrates.

scholarly journals Microwave Assisted Synthesis of 1,5-Benzothiazepines Using Greener Reaction Medium

2019 ◽  
Vol 31 (5) ◽  
pp. 993-996 ◽  
Author(s):  
Sanjay S. Kotalwar ◽  
Amol D. Kale ◽  
Ram B. Kohire ◽  
Vasant B. Jagrut
Keyword(s):  
Reaction Time ◽  
Microwave Irradiation ◽  
Reaction Medium ◽  
Microwave Assisted Synthesis ◽  
Reaction Conditions ◽  
Renewable Sources ◽  
Microwave Assisted ◽  
High Yields

An efficient and eco-friendly synthesis of 1,5-benzothiazepines has been developed by the reaction of various 2-propen-1-ones with 2-aminothiophenol using microwave irradiation in greener reaction medium, glycerol. The clean reaction conditions, shorter reaction time, high yields and non-toxic, biodegradable reaction medium manufactured from renewable sources are unique features of this method.

scholarly journals Microwave assisted synthesis of five membered nitrogen heterocycles

RSC Advances ◽  
2020 ◽  
Vol 10 (59) ◽  
pp. 36031-36041
Author(s):  
Gopinadh Meera ◽  
K. R. Rohit ◽  
Salim Saranya ◽  
Gopinathan Anilkumar
Keyword(s):  
Reaction Time ◽  
Nitrogen Heterocycles ◽  
Product Formation ◽  
Microwave Assisted Synthesis ◽  
Short Reaction Time ◽  
Microwave Assisted ◽  
High Yields

Microwave assisted synthesis of N-heterocycles with short reaction time, high yields and high product purities along with a decrease in the rate of by-product formation.

Microwave assisted synthesis of chalcone and its polycyclic heterocyclic analogues as promising antibacterial agents: In vitro, in silico and DFT studies

2019 ◽  
Vol 1190 ◽  
pp. 77-85 ◽  
Author(s):  
Salman A. Khan ◽  
Abdullah M. Asiri ◽  
Najat Saeed M. Al-Ghamdi ◽  
Mohammad Asad ◽  
Mohie E.M. Zayed ◽  
...  
Keyword(s):  
In Silico ◽  
Antibacterial Agents ◽  
Microwave Assisted Synthesis ◽  
Dft Studies ◽  
Microwave Assisted

Experimental and DFT Studies of Organocatalytic Microwave-Assisted Reaction of Isatin Derivatives with Dinitrotoluenes

2017 ◽  
Vol 6 (5) ◽  
pp. 575-582 ◽  
Author(s):  
Jasneet Kaur ◽  
Nasarul Islam ◽  
Akshay Kumar ◽  
Swapandeep Singh Chimni
Keyword(s):  
Dft Studies ◽  
Microwave Assisted ◽  
Isatin Derivatives

MicrowavE Assisted hydrolysis of Meldrum'S Acid Derivatives and decarboxylation of Derived Malonic Acids

2003 ◽  
Vol 2003 (3) ◽  
pp. 174-175 ◽  
Author(s):  
V.B. Helavi ◽  
S.B. Solabannavar ◽  
U.V. Desai ◽  
R.B. Mane
Keyword(s):  
Carboxylic Acids ◽  
Meldrum's Acid ◽  
Meldrum’S Acid ◽  
Microwave Assisted ◽  
High Yields ◽  
Short Time ◽  
Hydrolysis Of ◽  
Meldrum's Acid Derivatives

Microwave induced hydrolysis of alkyl Medrum's acids and decarboxylation of derived malonic acids using poly-4-vinylpyridine as a catalyst gives high yields of carboxylic acids in a short time.

scholarly journals Microwave-assisted cyclizations promoted by polyphosphoric acid esters: a general method for 1-aryl-2-iminoazacycloalkanes

2016 ◽  
Vol 12 ◽  
pp. 2026-2031 ◽  
Author(s):  
Jimena E Díaz ◽  
María C Mollo ◽  
Liliana R Orelli
Keyword(s):  
Polyphosphoric Acid ◽  
General Procedure ◽  
Reaction Times ◽  
Ring Closure ◽  
Heterocyclic Synthesis ◽  
Microwave Assisted ◽  
Solvent Free Conditions ◽  
High Yields ◽  
Acid Esters ◽  
General Method

The first general procedure for the synthesis of 5 to 7-membered 1-aryl-2-iminoazacycloalkanes is presented, by microwave-assisted ring closure of ω-arylaminonitriles promoted by polyphosphoric acid (PPA) esters. 1-Aryl-2-iminopyrrolidines were easily prepared from the acyclic precursors employing a chloroformic solution of ethyl polyphosphate (PPE). The use of trimethylsilyl polyphosphate (PPSE) in solvent-free conditions allowed for the synthesis of 1-aryl-2-iminopiperidines and hitherto unreported 1-aryl-2-iminoazepanes. The cyclization reaction involves good to high yields and short reaction times, and represents a novel application of PPA esters in heterocyclic synthesis.

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