A new restricted access molecularly imprinted fiber for direct solid phase microextraction of benzodiazepines from plasma samples

The Analyst ◽  
2019 ◽  
Vol 144 (14) ◽  
pp. 4320-4330 ◽  
Author(s):  
Lailah Cristina de Carvalho Abrão ◽  
Eduardo Costa Figueiredo
Keyword(s):  
Sample Preparation ◽  
Molecularly Imprinted Polymers ◽  
Binding Sites ◽  
Solid Phase Microextraction ◽  
Solid Phase ◽  
Plasma Samples ◽  
Molecularly Imprinted ◽  
Restricted Access ◽  
Imprinted Polymers ◽  
Direct Solid

Restricted access molecularly imprinted polymers (RAMIPs) are hybrid materials that present selective binding sites for a template (or similar molecules), and an external hydrophilic layer that avoids the binding of proteins to the material, making them appropriate for the sample preparation of protein fluids.

scholarly journals Restricted Access Molecularly Imprinted Polymers for Biological Sample Preparation

2021 ◽  
Vol 9 (35) ◽  
Author(s):  
Tássia Mendes ◽  
Mariana Rosa ◽  
Eduardo Figueiredo
Keyword(s):  
Sample Preparation ◽  
Molecularly Imprinted Polymers ◽  
Biological Sample ◽  
Organic Molecules ◽  
Solid Phase ◽  
Molecularly Imprinted ◽  
Restricted Access ◽  
Small Organic Molecules ◽  
Imprinted Polymers ◽  
Hydrophilic Monomer

Restricted access molecularly imprinted polymers (RAMIPs) have been efficiently used for the extraction of small organic molecules from untreated biological matrices (e.g. blood, plasma, serum, and milk). These materials have been obtained by modifying the external surface of conventional molecularly imprinted polymers (MIPs) with hydrophilic monomer grafting, crosslinked protein capsule or a combination of both. These sorbents aggregate the selectivity of MIPs with the ability to exclude macromolecules of restricted access materials (RAMs), being widely employed in solid phase extraction techniques, beyond their use in sensors. In this review, we discuss about the design and application of RAMIPs in biological sample preparation, emphasizing the future trends and remaining challenges of this technology for bioanalyses.

Highly selective enrichment and direct determination of imazethapyr residues from milk using magnetic solid-phase extraction based on restricted-access molecularly imprinted polymers

2021 ◽  
Author(s):  
Shicong Jia ◽  
yanqiang zhou ◽  
Jianmin Li ◽  
Bolin Gong ◽  
Shujuan Ma ◽  
...  
Keyword(s):  
Solid Phase Extraction ◽  
Molecularly Imprinted Polymers ◽  
Solid Phase ◽  
Direct Determination ◽  
Magnetic Solid Phase Extraction ◽  
Phase Extraction ◽  
Molecularly Imprinted ◽  
Restricted Access ◽  
Imprinted Polymers ◽  
Magnetic Solid

The restricted access media magnetic molecularly imprinted polymers (RAM-MMIPs) were prepared as magnetic solid phase extraction (M-SPE) material by reversible addition fragmentation chain transfer (RAFT) technique. The resulting RAM-MMIPs had...

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