scholarly journals Label-free counting of affinity-enriched circulating tumor cells (CTCs) using a thermoplastic micro-Coulter counter (μCC)

The Analyst ◽  
2020 ◽  
Vol 145 (5) ◽  
pp. 1677-1686
Author(s):  
Cong Kong ◽  
Mengjia Hu ◽  
Kumuditha M. Weerakoon-Ratnayake ◽  
Malgorzata A. Witek ◽  
Kavya Dathathreya ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Low Cost ◽  
Circulating Tumor Cell ◽  
Free Cell ◽  
Coulter Counter ◽  
Fabrication Process ◽  
Cell Counting ◽  
Label Free

A micro-Coulter Counter (μCC) with simple and low cost fabrication process was developed and integrated with a circulating tumor cell (CTC) selection chip, providing label-free cell counting for CTC analysis.

Circulating tumor cell detection using a parallel flow micro-aperture chip system

Lab on a Chip ◽  
2015 ◽  
Vol 15 (7) ◽  
pp. 1677-1688 ◽  
Author(s):  
Chun-Li Chang ◽  
Wanfeng Huang ◽  
Shadia I. Jalal ◽  
Bin-Da Chan ◽  
Aamer Mahmood ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Circulating Tumor Cell ◽  
Parallel Flow ◽  
Cell Detection ◽  
Tumor Cell Detection ◽  
System P

A parallel flow micro-aperture chip system for detection of circulating tumor cells.

scholarly journals Microfluidics-enabled rapid manufacturing of hierarchical silica-magnetic microflower toward enhanced circulating tumor cell screening

2018 ◽  
Vol 6 (12) ◽  
pp. 3121-3125 ◽  
Author(s):  
Nanjing Hao ◽  
Yuan Nie ◽  
Amogha Tadimety ◽  
Ting Shen ◽  
John X. J. Zhang
Keyword(s):  
Tumor Cell ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Circulating Tumor Cell ◽  
Rapid Manufacturing ◽  
Screening Efficiency

Microfluidics-enabled rapid manufacturing of a hierarchical silica-magnetic microflower was developed for improving the screening efficiency of circulating tumor cells.

scholarly journals A novel device to capture circulating tumor cells: Quantification and molecular analysis in lung cancer patients

2020 ◽  
Vol 35 (1) ◽  
pp. 49-58 ◽  
Author(s):  
Yuxin Cheng ◽  
Jie Shen ◽  
Ling Yuan ◽  
Yan Yang ◽  
Xiaoyan Shen ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Patients ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Low Cost ◽  
Circulating Tumor Cell ◽  
Tumor Evolution ◽  
Lung Cancer Patients ◽  
New Device ◽  
Novel Device

Here, we describe a novel microfilter device to capture circulating tumor cells in an efficient and low-cost manner. Then, we validated the safety and clinical utility of the novel microfilter device. We next performed mutation analysis from circulating tumor cells collected from lung cancer patients using this new device. Our results indicate that this microfilter system can be used to investigate the genome landscape of circulating tumor cells collected from lung cancer patients. Further, our results highlight a proof-of-concept demonstration indicating that circulating tumor cell can be used for mutation profiling during tumor evolution, therapy prediction, and monitoring, with immediate clinical applicability.

scholarly journals Precision microfilters as an all in one system for multiplex analysis of circulating tumor cells

RSC Advances ◽  
2016 ◽  
Vol 6 (8) ◽  
pp. 6405-6414 ◽  
Author(s):  
Daniel L. Adams ◽  
R. Katherine Alpaugh ◽  
Stuart S. Martin ◽  
Monica Charpentier ◽  
Saranya Chumsri ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Circulating Tumor Cell ◽  
Clinical Testing ◽  
Multiplex Analysis

An all-in-one Circulating Tumor Cell (CTC) isolation platform with streamlined multiplex integration of proteomic and genomic clinical testing.

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