A fluorescent biosensor for highly specific and ultrasensitive detection of adenosine triphosphate based on ligation-triggered branched rolling circle amplification

2019 ◽  
Vol 11 (36) ◽  
pp. 4629-4636
Author(s):  
Hongxin Jiang ◽  
Guimei Han ◽  
Yaping Xu ◽  
Junxing Li ◽  
Xiaowei Liu ◽  
...  
Keyword(s):  
Adenosine Triphosphate ◽  
Rolling Circle Amplification ◽  
Dna Ligase ◽  
Ultrasensitive Detection ◽  
Selective Detection ◽  
Rolling Circle ◽  
T4 Dna Ligase ◽  
Fluorescent Sensing ◽  
Fluorescent Biosensor

A fluorescent sensing strategy for ultrasensitive and highly selective detection of ATP was presented by taking advantage of the exponential amplification capability of BRCA and the extreme specificity of T4 DNA ligase toward ATP.

Target-responsive dumbbell probe-mediated rolling circle amplification strategy for highly sensitive Hg2+ detection

RSC Advances ◽  
2014 ◽  
Vol 4 (51) ◽  
pp. 27091-27097 ◽  
Author(s):  
Qingwang Xue ◽  
Yanqin Lv ◽  
Yuanfu Zhang ◽  
Shuling Xu ◽  
Qiaoli Yue ◽  
...  
Keyword(s):  
Rolling Circle Amplification ◽  
Selective Detection ◽  
Label Free ◽  
Rolling Circle ◽  
Fluorescent Sensing ◽  
Highly Sensitive ◽  
Mercuric Ions ◽  
Amplification Strategy

A novel label-free amplified fluorescent sensing scheme based on target-responsive dumbbell probe-mediated rolling circle amplification (D-RCA) has been developed for sensitive and selective detection of mercuric ions.

Amplified visual detection of microRNA-378 through a T4 DNA ligase-mediated circular template specific to target and target-triggering rolling circle amplification

2019 ◽  
Vol 11 (15) ◽  
pp. 2082-2088 ◽  
Author(s):  
Zhanmin Liu ◽  
Yanming Wang ◽  
Liping Li ◽  
Junhai Li ◽  
Yuanyuan Yuan
Keyword(s):  
Gastric Cancer ◽  
Early Detection ◽  
Visual Detection ◽  
Rolling Circle Amplification ◽  
Serum Biomarker ◽  
Dna Ligase ◽  
Rolling Circle ◽  
T4 Dna Ligase ◽  
Circular Template

MicroRNA-378 (miRNA-378) is widely regarded as a novel noninvasive serum biomarker for early detection of gastric cancer.

Ultrasensitive detection of lung cancer-associated miRNAs by multiple primer-mediated rolling circle amplification coupled with a graphene oxide fluorescence-based (MPRCA-GO) sensor

The Analyst ◽  
2019 ◽  
Vol 144 (14) ◽  
pp. 4180-4187 ◽  
Author(s):  
Krissana Khoothiam ◽  
Kiatnida Treerattrakoon ◽  
Tawin Iempridee ◽  
Patraporn Luksirikul ◽  
Tararaj Dharakul ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Graphene Oxide ◽  
Cancer Diagnosis ◽  
Rolling Circle Amplification ◽  
Ultrasensitive Detection ◽  
Rolling Circle

MPRCA-GO sensor can detect low amount of miRNAs, which are biomarkers in cancer diagnosis.

A facile scanometric strategy for ultrasensitive detection of protein using aptamer-initiated rolling circle amplification

2010 ◽  
Vol 46 (36) ◽  
pp. 6720 ◽  
Author(s):  
Wei Cheng ◽  
Lin Ding ◽  
Yunlong Chen ◽  
Feng Yan ◽  
Huangxian Ju ◽  
...  
Keyword(s):  
Rolling Circle Amplification ◽  
Ultrasensitive Detection ◽  
Rolling Circle

Ultrasensitive detection of T-2 toxin in food based on bio-barcode and rolling circle amplification

2018 ◽  
Vol 1043 ◽  
pp. 98-106 ◽  
Author(s):  
Man Zhang ◽  
Bingyang Huo ◽  
Shuai Yuan ◽  
Baoan Ning ◽  
Jialei Bai ◽  
...  
Keyword(s):  
Rolling Circle Amplification ◽  
Ultrasensitive Detection ◽  
Rolling Circle

A ratiometric electrochemical biosensor for ultrasensitive and highly selective detection of the K-ras gene via exonuclease III-assisted target recycling and rolling circle amplification strategies

2019 ◽  
Vol 11 (32) ◽  
pp. 4146-4156 ◽  
Author(s):  
Qi Xiao ◽  
Jinrong Feng ◽  
Jiawen Li ◽  
Yi Liu ◽  
Dan Wang ◽  
...  
Keyword(s):  
Electrochemical Biosensor ◽  
Rolling Circle Amplification ◽  
Selective Detection ◽  
Ras Gene ◽  
Exonuclease Iii ◽  
Target Recycling ◽  
Rolling Circle ◽  
Exo Iii

A ratiometric electrochemical biosensor for ultrasensitive and highly selective detection of the K-ras gene via Exo III-assisted target recycling and RCA strategies.

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