Molecular engineering of a high quantum yield NIR-II molecular fluorophore with aggregation-induced emission (AIE) characteristics for in vivo imaging

Nanoscale ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 5084-5090 ◽  
Author(s):  
Pengfei Xu ◽  
Fei Kang ◽  
Weidong Yang ◽  
Mingru Zhang ◽  
Ruili Dang ◽  
...  
Keyword(s):  
Quantum Yield ◽  
Fluorescence Imaging ◽  
In Vivo Imaging ◽  
Molecular Engineering ◽  
High Quantum Yield ◽  
Aggregation Induced Emission ◽  
High Quantum

Novel biocompatible NIR-II fluorophore with AIE characteristics has been developed and used for NIR-II biomedical fluorescence imaging.

scholarly journals Synthesis and Properties of Sulfhydryl-Reactive Near-Infrared Cyanine Fluorochromes for Fluorescence Imaging

2003 ◽  
Vol 2 (2) ◽  
pp. 153535002003031
Author(s):  
Yuhui Lin ◽  
Ralph Weissleder ◽  
Ching-Hsuan Tung
Keyword(s):  
Quantum Yield ◽  
Fluorescence Imaging ◽  
Biomedical Imaging ◽  
Near Infrared ◽  
Chemical Properties ◽  
High Quantum Yield ◽  
Affinity Ligands ◽  
High Quantum ◽  
And Chemical Properties

Near-infrared fluorochromes (NIRF) are useful compounds for diverse biotechnology applications and for in vivo biomedical imaging. Such NIRF must have high quantum yield, be biocompatible, and be conjugatable to a wide variety of proteins, peptides, and other affinity ligands. Here, we describe the synthesis of four new nonsymmetrical sulfhydryl-reactive cyanine NIRF with excellent optical and chemical properties. Each fluorochrome was designed to contain an iodoacetamido group that reacts specifically with sulfhydryl-containing molecules. The synthesized fluorochromes were used to label model peptides and sulfhydryl-containing biomolecules.

High-Quantum-Yield Mitochondria-Targeting Near-Infrared Fluorescent Probe for Imaging Native Hypobromous Acid in Living Cells and in Vivo

2017 ◽  
Vol 89 (3) ◽  
pp. 1787-1792 ◽  
Author(s):  
Xiaojun Liu ◽  
Aishan Zheng ◽  
Dongrui Luan ◽  
Xiaoting Wang ◽  
Fanpeng Kong ◽  
...  
Keyword(s):  
Quantum Yield ◽  
Fluorescent Probe ◽  
Near Infrared ◽  
Living Cells ◽  
High Quantum Yield ◽  
High Quantum ◽  
Hypobromous Acid ◽  
Mitochondria Targeting

scholarly journals Development of a high quantum yield dye for tumour imaging

2017 ◽  
Vol 8 (9) ◽  
pp. 6322-6326 ◽  
Author(s):  
Dan Yang ◽  
Huasen Wang ◽  
Chengjie Sun ◽  
Hui Zhao ◽  
Kuan Hu ◽  
...  
Keyword(s):  
Quantum Yield ◽  
Fluorescence Quantum Yield ◽  
Fluorescent Dye ◽  
Tumour Imaging ◽  
High Quantum Yield ◽  
High Quantum ◽  
High Fluorescence ◽  
High Fluorescence Quantum Yield

An easily accessible fluorescent dye, FEB, which has a high fluorescence quantum yield and is suitable forin vivotumour imaging is reported.

Organic nanoparticles with ultrahigh quantum yield and aggregation-induced emission characteristics for cellular imaging and real-time two-photon lung vasculature imaging

2018 ◽  
Vol 6 (17) ◽  
pp. 2630-2636 ◽  
Author(s):  
Jie Liu ◽  
Maximilien Evrard ◽  
Xiaolei Cai ◽  
Guangxue Feng ◽  
Nikodem Tomczak ◽  
...  
Keyword(s):  
Quantum Yield ◽  
Real Time ◽  
Cellular Imaging ◽  
Emission Characteristics ◽  
High Quantum Yield ◽  
Organic Nanoparticles ◽  
Aggregation Induced Emission ◽  
Two Photon ◽  
High Quantum

Organic nanoparticles with a high quantum yield of 90% and aggregation-induced emission characteristics were prepared for cellular imaging and real-time two-photon vasculature imaging of the lungs.

Molecular Engineering of an Organic NIR‐II Fluorophore with Aggregation‐Induced Emission Characteristics for In Vivo Imaging

Small ◽  
2019 ◽  
Vol 15 (20) ◽  
pp. 1805549 ◽  
Author(s):  
Wei Wu ◽  
Yanqing Yang ◽  
Yang Yang ◽  
Yuming Yang ◽  
Kaiyuan Zhang ◽  
...  
Keyword(s):  
In Vivo Imaging ◽  
Molecular Engineering ◽  
Emission Characteristics ◽  
Aggregation Induced Emission

Superior Stable and High Quantum Yield Phosphor Na2BaSr(PO4)2: Eu2+ for Plant Growth LEDs

2021 ◽  
Author(s):  
Jinmeng Xiang ◽  
Xiaoqi Zhao ◽  
Hao Suo ◽  
Minkun Jin ◽  
Xue Zhou ◽  
...  
Keyword(s):  
Quantum Yield ◽  
Plant Growth ◽  
Light Emitting Diodes ◽  
Light Environment ◽  
High Quantum Yield ◽  
Light Emitting ◽  
Growth Rhythm ◽  
High Quantum ◽  
Violet Light ◽  
Important Means

Controlling the light environment of plant growth using phosphor-converted light-emitting diodes (pc-LEDs) is an important means to regulate the growth rhythm and enhance the yield, in which bluish violet light...

Sensitive and specific detection of peroxynitrite and in-vivo imaging of inflammation by a "simple" AIE bioprobe

2021 ◽  
Author(s):  
Huilin Xie ◽  
Jingtian Zhang ◽  
Chao Chen ◽  
Feiyi Sun ◽  
Haixiang Liu ◽  
...  
Keyword(s):  
In Vivo Imaging ◽  
Fluorescence Enhancement ◽  
Specific Detection ◽  
Aggregation Induced Emission

A luminogenic bioprobe TPE-DMAB for simple and specific detection of peroxynitrite (ONOO−) has been developed. TPE-DMAB exhibits aggregation-induced emission (AIE) characteristic and shows fluorescence enhancement (up to 100-fold) upon cleavage...

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