[Ag(bpy)(PPhtBu2)(OCF3)]: a stable nucleophilic reagent for chemoselective and stereospecific trifluoromethoxylation of secondary alkyl nosylates

2019 ◽  
Vol 6 (11) ◽  
pp. 1801-1806 ◽  
Author(s):  
Daoqian Chen ◽  
Long Lu ◽  
Qilong Shen
Keyword(s):  
Room Temperature ◽  
Nucleophilic Reagent ◽  
Thermally Stable ◽  
One Pot ◽  
High Yields

The development of a thermally stable and light-insensitive nucleophilic trifluoromethoxylative reagent [Ag(bpy)(PPhtBu2)(OCF3)] 2, which was synthesized in high yields via a three-step one-pot process from easily available trifluoromethyl triflate (TFMT) and AgF at room temperature, is described.

UV-Light-Induced Dehydrogenative N-Acylation of Amines with 2-Nitrobenzaldehydes to Give 2-Aminobenzamides

Synthesis ◽  
2022 ◽  
Author(s):  
Dishu Zeng ◽  
Tianbao Yang ◽  
Niu Tang ◽  
Wei Deng ◽  
Jiannan Xiang ◽  
...  
Keyword(s):  
Amino Acid ◽  
Organic Synthesis ◽  
Efficient Method ◽  
Building Block ◽  
Room Temperature ◽  
Uv Light ◽  
Amino Acid Derivatives ◽  
One Pot ◽  
Plausible Mechanism ◽  
High Yields

A simple, mild, green and efficient method for the synthesis of 2-aminobenzamides was highly desired in organic synthesis. Herein, we developed an efficient, one-pot strategy for the synthesis of 2-aminobenzamides with high yields irradiated by UV light. 32 examples proceeded successfully by this photo-induced protocol. The yield reached up to 92%. The gram scale was also achieved easily. This building block could be applied in the preparation of quinazolinones derivatives. Amino acid derivatives could be employed smoothly at room temperature. Finally, a plausible mechanism was proposed.

scholarly journals A Facile Synthesis of Polysubstituted Pyrroles by One-Pot Three-Component Reaction

2012 ◽  
Vol 9 (4) ◽  
pp. 2239-2244 ◽  
Author(s):  
Hossein Anaraki-Ardakani ◽  
Maziar Noei ◽  
Mina Karbalaei-Harofteh ◽  
Shahab Zomorodbakhsh
Keyword(s):  
Room Temperature ◽  
Facile Synthesis ◽  
One Pot ◽  
Pyrrole Derivatives ◽  
Dialkyl Acetylenedicarboxylates ◽  
One Pot Synthesis ◽  
Three Component Reaction ◽  
High Yields ◽  
Neutral Conditions

A new and efficient one-pot synthesis of polysubstituted pyrrole derivatives by three-component reaction between dialkyl acetylenedicarboxylates, triphenylphosphine, 2-aminopyridin derivatives in the presence of arylglyoxals is described. The reactions were performed in dichloromethane at room temperature and neutral conditions and afforded high yields of products.

A Copper(I)-Mediated Tandem Three-Component Synthesis of 5-Allyl-1,2,3-triazoles

Synthesis ◽  
2019 ◽  
Vol 52 (05) ◽  
pp. 744-754
Author(s):  
Yoona Song ◽  
Soyun Lee ◽  
Palash Dutta ◽  
Jae-Sang Ryu
Keyword(s):  
Room Temperature ◽  
Reaction Conditions ◽  
One Pot ◽  
Three Component Reaction ◽  
High Yields

A copper(I)-mediated tandem three-component reaction using alkynes, azides, allyl iodides, CuI and NaNH2 is developed. The reactions proceed smoothly at room temperature to afford 5-allyl-1,2,3-triazoles, which can be further converted into 1,2,3-triazole-fused tricyclic scaffolds. This method features an efficient one-pot cascade route using commercial alkynes and affords the corresponding 5-allyl-1,2,3-triazoles with high yields and good selectivity under mild reaction conditions.

scholarly journals Efficient one-pot, four-component synthesis of N,N-dibenzyl-N-{1-[5-(3-aryl)-1,3,4-oxadiazol-2-yl]cyclobutyl}amine derivatives from the reaction of (isocyanoimino)triphenylphosphorane, dibenzylamine, an aromatic carboxylic acid and cyclobutanone

2012 ◽  
Vol 77 (9) ◽  
pp. 1175-1180 ◽  
Author(s):  
Nahid Shajari ◽  
Reza Kazemizadeh ◽  
Ali Ramazani
Keyword(s):  
Carboxylic Acid ◽  
Carboxylic Acids ◽  
Room Temperature ◽  
Aromatic Carboxylic Acid ◽  
One Pot ◽  
Aromatic Carboxylic Acids ◽  
High Yields ◽  
Neutral Conditions

Four-component reaction of cyclobutanone, dibenzylamine and (Nisocyanimino) triphenylphosphorane in the presence of aromatic carboxylic acids proceed smoothly at room temperature and under neutral conditions to afford N,N-dibenzyl-N-{1-[5-(3-aryl)-1,3,4-oxadiazol-2-yl]cyclobutyl}amine derivatives in high yields.

scholarly journals A Green, Expeditious, One-Pot Synthesis of 3, 4-Dihydropyrimidin-2(1H)-ones Using a Mixture of Phosphorus Pentoxide-Methanesulfonic Acid at Ambient Temperature

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Amulrao Borse ◽  
Mahesh Patil ◽  
Nilesh Patil ◽  
Rohan Shinde
Keyword(s):  
Reaction Time ◽  
Ambient Temperature ◽  
Room Temperature ◽  
Simple Procedure ◽  
Methanesulfonic Acid ◽  
Phosphorus Pentoxide ◽  
One Pot ◽  
Short Reaction Time ◽  
Solvent Free Conditions ◽  
High Yields

An expeditious, one-pot method for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones using a mixture of phosphorus pentoxide-methanesulfonic acid (Eaton’s reagent) at room temperature under solvent-free conditions is described. The salient features of this method include short reaction time, green aspects, high yields, and simple procedure.

scholarly journals Three-Component One-Pot Synthesis of Novel Benzo[b]1,8-naphthyridines Catalyzed by Bismuth(III) Chloride

2008 ◽  
Vol 2008 ◽  
pp. 1-4
Author(s):  
Tangali R. Ravikumar Naik ◽  
Halehatty S. Bhojya Naik ◽  
Halehatty R. Prakasha Naik ◽  
P. J. Bindu
Keyword(s):  
Room Temperature ◽  
Environmentally Friendly ◽  
Aromatic Aldehydes ◽  
One Pot ◽  
One Pot Synthesis ◽  
High Yields

A novel and efficient three-component one-pot synthesis of benzo[b]1,8-naphthyridines by 2-amino-4-methylquinoline, aromatic aldehydes, and malononitrile was done. The reaction was catalyzed by an acidic Bismuth(III) chloride, functionalized Bismuth(III) chloride, at room temperature to give various benzo[b]1,8-naphthyridines in high yields. The Bismuth(III) chloride is an environmentally friendly catalyst.

scholarly journals An Efficient Isocyanide-Based Three-Component Synthesis of Novel Ketenimines

2014 ◽  
Vol 10 (3) ◽  
pp. 2363-2368
Author(s):  
Hamideh Emtiazi ◽  
Mohammad Ali Amrollahi
Keyword(s):  
Room Temperature ◽  
Simple Procedure ◽  
Reaction Times ◽  
Dimethyl Acetylenedicarboxylate ◽  
One Pot ◽  
Three Component Reaction ◽  
High Yields

This study provides a description of an efficient and simple procedure for the synthesis of dimethyl 2-(9-aryl)-3,3,6,6-tetramethyl-1,8-diox-1,2,3,4,5,6,7,8-octahydroacridin-10(9H)-yl)-3-((cyclohexylimino)methylene)succinate via a one-pot three-component reaction of cyclohexyl isocyanide, dimethyl acetylenedicarboxylate and hexahydroacridine-1,8(2H,5H)-dionesin CH2Cl2 at room temperature. Short reaction times, good to high yields and the novelty are the remarkable advantages of this work.

One-pot Nitration of Phenols under Mild and Heterogeneous Conditions

2001 ◽  
Vol 2001 (4) ◽  
pp. 140-142 ◽  
Author(s):  
Mohammad Ali Zolfigol ◽  
Mojtaba Bagherzadeh ◽  
Elahe Madrakian ◽  
Ezat Ghaemi ◽  
Abolfazl Taqian-Nasab
Keyword(s):  
Radical Cation ◽  
Nitrous Acid ◽  
Room Temperature ◽  
Hydrogen Abstraction ◽  
One Pot ◽  
Oxidation Of Phenols ◽  
In Situ Generation ◽  
High Yields

Nitrophenols can be obtained via nitrosation–oxidation of phenols with Oxone®, NaNO2 and wet SiO2 at room temperature in moderate to high yields. In situ generation of HNO2 and the radical cation mechanism via the nitrous acid catalysed (NAC) pathway or hydrogen abstraction involving NO2 appear to be applicable to phenol nitration using these reagents.

A Novel One-pot Protocol for the Cu-Catalyzed Synthesis of Nine 2-Aminobenzimidazole Derivatives from o-Phenylenediamine and Trichloroacetonitrile

2019 ◽  
Vol 16 (2) ◽  
pp. 99-103 ◽  
Author(s):  
Manijeh Nematpour ◽  
Elham Abedi ◽  
Elahe Abedi
Keyword(s):  
Column Chromatography ◽  
Room Temperature ◽  
Free Ligand ◽  
One Pot ◽  
High Yields

The synthesis of a variety of 2-aminobenzimidazoles via a one pot reaction of ophenylenediamine and trichloroacetonitrile catalyzed by copper (II) acetate in THF at room temperature, with good yields is described. Use of simple and readily available starting materials, good to high yields, free ligand, and no column chromatography are important features of this protocol.

Silica Nanoparticles from Rice Husk Ash: A Green Catalyst for the One-Pot Three-Component Synthesis of Benzo[B]Furan Derivatives

2014 ◽  
Vol 875-877 ◽  
pp. 202-207 ◽  
Author(s):  
Ali Ramazani ◽  
Morteza Rouhani ◽  
Sang Woo Joo
Keyword(s):  
Silica Nanoparticles ◽  
Rice Husk ◽  
Room Temperature ◽  
Rice Husk Ash ◽  
One Pot ◽  
Furan Derivatives ◽  
Green Catalyst ◽  
Iminium Ion ◽  
The One ◽  
High Yields

Reaction of an isocyanide with an iminium ion intermediate, formed by reaction between an electronpoor 2-hydroxybenzaldehyde derivative and a secondary amine in the presence of silica nanoparticles proceeds smoothly at room temperature to afford benzo [b] furan derivatives in high yields.

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