scholarly journals A reactive oxygen species-generating, cancer stem cell-potent manganese(ii) complex and its encapsulation into polymeric nanoparticles

2019 ◽  
Vol 10 (33) ◽  
pp. 7792-7800 ◽  
Author(s):  
Arvin Eskandari ◽  
Kogularamanan Suntharalingam
Keyword(s):  
Breast Cancer ◽  
Reactive Oxygen Species ◽  
Stem Cell ◽  
Cancer Stem Cell ◽  
Polymeric Nanoparticles ◽  
Reactive Oxygen ◽  
Breast Cancer Stem Cell ◽  
Oxygen Species ◽  
Inflammatory Drug ◽  
Phenanthroline Complex

Here we report the breast cancer stem cell (CSC) potency of a reactive oxygen species (ROS)-generating manganese(ii)-phenanthroline complex bearing diclofenac, a nonsteriodial anti-inflammatory drug.

scholarly journals A reactive oxygen species-generating, cyclooxygenase-2 inhibiting, cancer stem cell-potent tetranuclear copper(ii) cluster

2017 ◽  
Vol 46 (38) ◽  
pp. 12785-12789 ◽  
Author(s):  
C. Lu ◽  
K. Laws ◽  
A. Eskandari ◽  
K. Suntharalingam
Keyword(s):  
Reactive Oxygen Species ◽  
Stem Cells ◽  
Schiff Base ◽  
Stem Cell ◽  
Cancer Stem Cells ◽  
Cancer Stem Cell ◽  
Cancer Cells ◽  
Reactive Oxygen ◽  
Cyclooxygenase 2 ◽  
Oxygen Species

Tetranuclear copper(ii) complexes containing multiple diclofenac and Schiff base moieties,1–4, are shown to kill bulk cancer cells and cancer stem cells (CSCs) with low micromolar potency.

scholarly journals Breast Cancer Stem Cell Potent Copper(II)-Non-Steroidal Anti-Inflammatory Drug Complexes

2016 ◽  
Vol 128 (8) ◽  
pp. 2895-2900 ◽  
Author(s):  
Janine N. Boodram ◽  
Iain J. Mcgregor ◽  
Peter M. Bruno ◽  
Paul B. Cressey ◽  
Michael T. Hemann ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Stem Cell ◽  
Cancer Stem Cell ◽  
Breast Cancer Stem Cell ◽  
Inflammatory Drug ◽  
Anti Inflammatory

scholarly journals Breast Cancer Stem Cell Potent Copper(II)-Non-Steroidal Anti-Inflammatory Drug Complexes

2016 ◽  
Vol 55 (8) ◽  
pp. 2845-2850 ◽  
Author(s):  
Janine N. Boodram ◽  
Iain J. Mcgregor ◽  
Peter M. Bruno ◽  
Paul B. Cressey ◽  
Michael T. Hemann ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Stem Cell ◽  
Cancer Stem Cell ◽  
Breast Cancer Stem Cell ◽  
Inflammatory Drug ◽  
Anti Inflammatory

scholarly journals The breast cancer stem cell potency of copper(ii) complexes bearing nonsteroidal anti-inflammatory drugs and their encapsulation using polymeric nanoparticles

2016 ◽  
Vol 45 (44) ◽  
pp. 17867-17873 ◽  
Author(s):  
Arvin Eskandari ◽  
Janine N. Boodram ◽  
Paul B. Cressey ◽  
Chunxin Lu ◽  
Peter M. Bruno ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Stem Cell ◽  
Cancer Stem Cell ◽  
Metal Complexes ◽  
Polymeric Nanoparticles ◽  
Breast Cancer Stem Cell ◽  
First Report ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

This is the first report to demonstrate that polymeric nanoparticles can be used to effectively deliver CSC-potent metal complexes into CSCs.

Regulation of Breast Cancer Stem Cell by Tissue Rigidity

2015 ◽  
Author(s):  
Jing Yang ◽  
Adam Engler ◽  
Laurent Fattet ◽  
Matthew Ondeck
Keyword(s):  
Breast Cancer ◽  
Stem Cell ◽  
Cancer Stem Cell ◽  
Breast Cancer Stem Cell
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