scholarly journals Ratiometric fluorescence imaging of Golgi H2O2 reveals a correlation between Golgi oxidative stress and hypertension

2019 ◽  
Vol 10 (47) ◽  
pp. 10876-10880 ◽  
Author(s):  
Hui Wang ◽  
Zixu He ◽  
Yuyun Yang ◽  
Jiao Zhang ◽  
Wei Zhang ◽  
...  

Based on a novel Golgi-targeting phenylsulfonamide group, a two-photon (TP) fluorescent probe, Np-Golgi, was developed for in situ H2O2 ratiometric imaging in living systems.

2019 ◽  
Vol 11 (12) ◽  
pp. 1580-1584 ◽  
Author(s):  
Li Wang ◽  
Mingguang Ren ◽  
Zihong Li ◽  
Lixuan Dai ◽  
Weiying Lin

We developed a new ratiometric two-photon fluorescent probe (CR-HA). Fluorescence imaging showed that CR-HA was suitable for the visualization of HOCl changes in living cells/tissues.


2020 ◽  
Vol 56 (9) ◽  
pp. 1349-1352 ◽  
Author(s):  
Wei Li ◽  
Shulu Yin ◽  
Xiangyang Gong ◽  
Wang Xu ◽  
Ronghua Yang ◽  
...  

A novel two-photon ratiometric fluorescence assay was proposed for monitoring endogenous steroid sulfatase (STS) activity, which achieved the ratiometric imaging of STS activity in the endoplasmic reticulum of living cells and tissues.


2019 ◽  
Vol 91 (21) ◽  
pp. 14101-14108 ◽  
Author(s):  
Ye Jin Reo ◽  
Yong Woong Jun ◽  
Sourav Sarkar ◽  
Mingchong Dai ◽  
Kyo Han Ahn

2016 ◽  
Vol 40 (9) ◽  
pp. 7399-7406 ◽  
Author(s):  
Fangfang Meng ◽  
Yong Liu ◽  
Xiaoqiang Yu ◽  
Weiying Lin

In this work, we developed a dual-site two-photon (TP) fluorescent RSH probe (CA-TPP) for imaging mitochondrial RSH in living systems. In particular, probe CA-TPP was capable of using TP fluorescence to track mitochondrial RSH over a long period for the first time.


2019 ◽  
Vol 2 (11) ◽  
pp. 4687-4692 ◽  
Author(s):  
Keqin Yang ◽  
Jingjin Zhao ◽  
Liangliang Zhang ◽  
Rongjun Liu ◽  
Hong Liang ◽  
...  

2018 ◽  
Vol 54 (84) ◽  
pp. 11965-11968 ◽  
Author(s):  
Xilei Xie ◽  
Tianhong Wu ◽  
Xu Wang ◽  
Yong Li ◽  
Kaiye Wang ◽  
...  

A fluorescent probe with superior sensing performance enables two-photon ratiometric imaging of biogenic hypochlorous acid in live cells and animals.


2019 ◽  
Vol 55 (47) ◽  
pp. 6767-6770 ◽  
Author(s):  
Yongqing Zhou ◽  
Ping Li ◽  
Nannan Fan ◽  
Xin Wang ◽  
Xiaoning Liu ◽  
...  

In situ visualization of peroxisomal peroxynitrite in the livers of mice with acute liver injury using a new two-photon fluorescent probe.


2019 ◽  
Vol 55 (76) ◽  
pp. 11358-11361 ◽  
Author(s):  
Ao Jiang ◽  
Guang Chen ◽  
Jie Xu ◽  
Yuxia Liu ◽  
Guanghui Zhao ◽  
...  

A probe for imaging of mitochondrial carboxylesterase and pH has been developed for the visualization of carboxylesterase-mediated acidification in hepatoma cells and hepatic tissues during the administration of antipyretic and anti-inflammatory drugs.


2019 ◽  
Vol 55 (86) ◽  
pp. 12912-12915 ◽  
Author(s):  
Yan Lou ◽  
Caixia Wang ◽  
Siyu Chi ◽  
Songjiao Li ◽  
Zhiqiang Mao ◽  
...  

A ratiometric two-photon fluorescent probe for HClO was deliberately constructed to reveal the generation of HClO in alcohol-induced liver injury.


2014 ◽  
Vol 86 (18) ◽  
pp. 9131-9138 ◽  
Author(s):  
Hua Zhang ◽  
Jiangli Fan ◽  
Kui Wang ◽  
Jing Li ◽  
Caixia Wang ◽  
...  

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