scholarly journals Reaction of 2,5-dihydroxy-[1,4]-benzoquinone with nucleophiles – ipso-substitution vs. addition/elimination

2020 ◽  
Vol 56 (84) ◽  
pp. 12845-12848
Author(s):  
Hubert Hettegger ◽  
Karin Steinkellner ◽  
Nele S. Zwirchmayr ◽  
Antje Potthast ◽  
Kevin J. Edgar ◽  
...  
Keyword(s):  
Elimination Reaction ◽  
Ipso Substitution

ipso-Substitution vs. addition/elimination reaction depending on the type of nucleophile reacting with 2,5-dihydroxy-[1,4]-benzoquinone (DHBQ).

ChemInform Abstract: RADICAL ALKYLDENITRATION. A SYNTHETICALLY USEFUL EXAMPLE OF HOMOLYTIC AROMATIC IPSO-SUBSTITUTION REACTIONS

1978 ◽  
Vol 9 (24) ◽  
Author(s):  
L. TESTAFERRI ◽  
M. TIECCO ◽  
M. TINGOLI ◽  
M. FIORENTINO ◽  
L. TROISI
Keyword(s):  
Substitution Reactions ◽  
Ipso Substitution

scholarly journals Studies on the Elimination Reaction of d-Amino Acid Oxidase with α-Amino-β-chlorobutyrate

1973 ◽  
Vol 248 (6) ◽  
pp. 1946-1955 ◽  
Author(s):  
Christopher T. Walsh ◽  
Elizabeth Krodel ◽  
Vincent Massey ◽  
Robert H. Abeles
Keyword(s):  
Amino Acid ◽  
Acid Oxidase ◽  
Elimination Reaction ◽  
Amino Acid Oxidase

scholarly journals Microbial Transsulfuration: the Mechanism of an Enzymatic Disulfide Elimination Reaction

1962 ◽  
Vol 237 (3) ◽  
pp. 768-777 ◽  
Author(s):  
Martin Flavin
Keyword(s):  
Elimination Reaction

scholarly journals Catalytic Antioxidant Activity of Bis-Aniline-Derived Diselenides as GPx Mimics

Molecules ◽  
2021 ◽  
Vol 26 (15) ◽  
pp. 4446
Author(s):  
Giancarlo V. Botteselle ◽  
Welman C. Elias ◽  
Luana Bettanin ◽  
Rômulo F. S. Canto ◽  
Drielly N. O. Salin ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Hydrogen Bond ◽  
Electronic Properties ◽  
Partial Charge ◽  
Amino Group ◽  
Diphenyl Diselenide ◽  
Charge Delocalization ◽  
Ipso Substitution ◽  
Efficient Route ◽  
Catalytic Performances

Herein, we describe a simple and efficient route to access aniline-derived diselenides and evaluate their antioxidant/GPx-mimetic properties. The diselenides were obtained in good yields via ipso-substitution/reduction from the readily available 2-nitroaromatic halides (Cl, Br, I). These diselenides present GPx-mimetic properties, showing better antioxidant activity than the standard GPx-mimetic compounds, ebselen and diphenyl diselenide. DFT analysis demonstrated that the electronic properties of the substituents determine the charge delocalization and the partial charge on selenium, which correlate with the catalytic performances. The amino group concurs in the stabilization of the selenolate intermediate through a hydrogen bond with the selenium.

Phosphonium salts. III. The action of cyanide ion and other nucleophiles on some bis-phosphonium salts

1969 ◽  
Vol 22 (7) ◽  
pp. 1405 ◽  
Author(s):  
JJ Brophy ◽  
MJ Gallagher
Keyword(s):  
Sodium Azide ◽  
Sodium Methoxide ◽  
Sodium Acetate ◽  
Potassium Cyanide ◽  
Dimethyl Sulphoxide ◽  
High Yield ◽  
Phosphonium Salts ◽  
Elimination Reaction ◽  
Cyanide Ion ◽  
Reaction Proceeds

Cyclic and acyclic bis-phosphonium salts with a two-carbon bridge are smoothly cleaved to phosphines in high yield by potassium cyanide in dimethyl sulphoxide. Evidence is presented that the reaction proceeds by an elimination-addition sequence. An elimination reaction also occurs when sodium methoxide, sodium azide, sodium acetate, and triethylamine react with ethane-1,2-bis(tri-phenylphosphonium) dibromide. ��� In a novel reaction, triphenylphosphine is converted into its oxide by a mixture of sodium azide and dimethyl sulphoxide.

ChemInform Abstract: Unusual Synthesis of New Glycine Antagonists via Sequential Aldol Condensation-Lactonization-Elimination Reaction.

ChemInform ◽  
2010 ◽  
Vol 29 (44) ◽  
pp. no-no
Author(s):  
S. A. GIACOBBE ◽  
D. BARALDI ◽  
R. DI FABIO
Keyword(s):  
Aldol Condensation ◽  
Elimination Reaction

MP2 study of substituent effects of 2-substituted alkyl ethyl methylcarbamates in homogeneous, unimolecular gas phase elimination reaction

2005 ◽  
Vol 732 (1-3) ◽  
pp. 55-61 ◽  
Author(s):  
Jesús M. Ruiz Gonzalez ◽  
Marcos Loroño ◽  
Tania Córdova ◽  
Gabriel Chuchani
Keyword(s):  
Gas Phase ◽  
Substituent Effects ◽  
Elimination Reaction ◽  
Phase Elimination
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