Three-spot seahorse-derived peptide PAGPRGPA attenuates ethanol-induced oxidative stress in LO2 cells through MAPKs, Keap1/Nrf2 signalling pathway and amino acid metabolism

2021 ◽  
Author(s):  
Jie Shi ◽  
Xin Zhou ◽  
Ying Zhao ◽  
Xuemei Tang ◽  
Lu Feng ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Liver Disease ◽  
Amino Acid ◽  
Global Health ◽  
Alcoholic Liver Disease ◽  
Liver Diseases ◽  
Amino Acid Metabolism ◽  
Bioactive Peptides ◽  
Acid Metabolism ◽  
Marine Organisms

Various types of liver diseases such as the alcoholic liver disease (ALD) are still global health problems. Bioactive peptides isolated from people, marine organisms, animals and plants have shown hepatoprotective...

scholarly journals Functional metabolomics using UPLC-Q/TOF-MS combined with ingenuity pathway analysis as a promising strategy for evaluating the efficacy and discovering amino acid metabolism as a potential therapeutic mechanism-related target for geniposide against alcoholic liver disease

RSC Advances ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. 2677-2690 ◽  
Author(s):  
Shi Qiu ◽  
Ai-hua Zhang ◽  
Yu Guan ◽  
Hui Sun ◽  
Tian-lei Zhang ◽  
...  
Keyword(s):  
Liver Disease ◽  
Amino Acid ◽  
Pathway Analysis ◽  
Alcoholic Liver Disease ◽  
Amino Acid Metabolism ◽  
Acid Metabolism ◽  
Promising Strategy ◽  
Therapeutic Mechanism ◽  
Functional Metabolomics ◽  
Tof Ms

Metabolomics has been used as a strategy to evaluate the efficacy of and potential targets for natural products.

A polysaccharide of PFP-1 from Pleurotus geesteranus attenuates alcoholic liver diseases via Nrf2 and NF-κB signaling pathways

2021 ◽  
Author(s):  
Xinling Song ◽  
Wenxue Sun ◽  
Wenxin Cai ◽  
Le Jia ◽  
Jianjun Zhang
Keyword(s):  
Oxidative Stress ◽  
Liver Disease ◽  
Liver Injury ◽  
Signaling Pathways ◽  
Alcoholic Liver Disease ◽  
Fruiting Body ◽  
Liver Diseases ◽  
Alcoholic Liver Diseases

A polysaccharide named as PFP-1 was isolated from Pleurotus geesteranus fruiting body, and the potential investigations on ameliorating oxidative stress and liver injury against alcoholic liver disease (ALD) were processed...

scholarly journals Branched chain amino acid metabolism profiles in progressive human nonalcoholic fatty liver disease

Amino Acids ◽  
2014 ◽  
Vol 47 (3) ◽  
pp. 603-615 ◽  
Author(s):  
April D. Lake ◽  
Petr Novak ◽  
Petia Shipkova ◽  
Nelly Aranibar ◽  
Donald G. Robertson ◽  
...  
Keyword(s):  
Liver Disease ◽  
Amino Acid ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Fatty Liver Disease ◽  
Amino Acid Metabolism ◽  
Acid Metabolism ◽  
Nonalcoholic Fatty Liver ◽  
Branched Chain Amino Acid ◽  
Branched Chain
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