In Situ Self-Assembled Peptide Nanofibers for Cancer Theranostics

2021 ◽  
Author(s):  
Ning Liu ◽  
Lianghan Zhu ◽  
Wenlong Liu ◽  
Zhaoting Li ◽  
Minjie Sun ◽  
...  

Self-assembled nanofibers hold tremendous promise for cancer theranostics owing to their in situ assembly, spatiotemporal responsiveness, and diverse bioactivity. Herein, this review summarizes recent advances of self-assembled peptide nanofibers and...

2021 ◽  
Author(s):  
Farouk Semcheddine ◽  
Nida El Islem Guissi ◽  
Weiwei Liu ◽  
Tayyaba Tayyaba ◽  
Gang Lv ◽  
...  

Chemically engineered nanomaterials have been extensively used in early tumor detection and cancer therapy. Despite the promises shown, some chemical or exogenous nature have hindered their application due to their...


2015 ◽  
Vol 15 (13) ◽  
pp. 1162-1178 ◽  
Author(s):  
Anna Ponomarenko ◽  
Vladimir Brylev ◽  
Elena Nozhevnikova ◽  
Vladimir Korshun

The Analyst ◽  
2021 ◽  
Author(s):  
Shan Huang ◽  
Yuexin Song ◽  
Zhimei He ◽  
Jian-Rong Zhang ◽  
Jun-Jie Zhu

Self-assembled nanomaterials (SANs) donate with designable biofunctions owing to their tunable nanostructures and modifiable surface. Various constituent units and multi-dimensional structures of SANs provide unlimited possibilities for numerous applications. This...


1999 ◽  
Vol 77 (5-6) ◽  
pp. 1077-1084 ◽  
Author(s):  
R Scott Reese ◽  
Marye Anne Fox

Self-assembled monolayers of sulfur-terminated oligonucleotide duplexes were formed on flat gold surfaces, either by exposure of a self-assembled monolayer bearing one oligonucleotide strand to the complementary strand or by preformation of a oligonucleotide duplex that was then deposited on a fresh gold surface. Virtually identical spectral behavior was observed whether the duplex was produced before deposition or by in situ complementary association. With a duplex bearing an appropriate pyrene end-label, the resulting thin film was photoresponsive. Surface emission measurements show no evidence for pyrene aggregation on the modified surfaces. The polarity of the photocurrent, reflecting photoinduced electron transfer initiated by photoexcitation of pyrene, is opposite that expected from the oligonucleotide-mediated reduction of the appended pyrene excited state.Key words: oligonucleotide, self-assembled monolayer, duplex formation, photoelectrochemistry, surface emission.


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