A NOVEL STRATEGY FOR DIRECT ELEMENTAL DETERMINATION USING LASER-INDUCED BREAKDOWN SPECTROSCOPY: FLUENCE CALIBRATION

Quantitative analysis requires several efforts to obtain an adequate calibration method to overcome matrix effects employing direct solid analysis by laser-induced breakdown spectroscopy (LIBS). To this end, in this study,...

Download Full-text

Matrix Effects in Quantitative Analysis of Laser-Induced Breakdown Spectroscopy (LIBS) of Rock Powders Doped with Cr, Mn, Ni, Zn, and Co

Applied Spectroscopy ◽

10.1177/0003702816685095 ◽

2017 ◽

Vol 71 (4) ◽

pp. 600-626 ◽

Cited By ~ 13

Author(s):

Kate H. Lepore ◽

Caleb I. Fassett ◽

Elly A. Breves ◽

Sarah Byrne ◽

Stephen Giguere ◽

...

Keyword(s):

Quantitative Analysis ◽

Matrix Effects ◽

Laser Induced Breakdown Spectroscopy ◽

Breakdown Spectroscopy ◽

Laser Induced Breakdown

Download Full-text

Application of Laser Induced Breakdown Spectroscopy in Soil Element Analysis of Watershed

MATEC Web of Conferences ◽

10.1051/matecconf/201824601114 ◽

2018 ◽

Vol 246 ◽

pp. 01114

Author(s):

C. P. Chen ◽

L. Hei ◽

S. C. Yu ◽

W. L. Chen ◽

M. X. Cai

Keyword(s):

Quantitative Analysis ◽

Elemental Analysis ◽

Matrix Effects ◽

Rapid Development ◽

Internal Standard ◽

Laser Induced Breakdown Spectroscopy ◽

Element Analysis ◽

Breakdown Spectroscopy ◽

Analysis Methods ◽

Laser Induced Breakdown

With the rapid development of spectroscopy technology, laser induced breakdown spectroscopy (LIBS) has become the focus of elemental analysis technology in recent years. With its advantages of non-destructive testing, rapid and multi-element detection, LIBS has been successfully applied to the analysis of geochemical characteristics of soil elements in river basins. The application of LIBS technology in soil elemental analysis of watershed is reviewed in detail. The accuracy of LIBS technology in soil element analysis is studied with the Masha River Basin as the research area. On this basis, the key problems in the process of soil element analysis, such as spectral enhancement methods and quantitative analysis methods, were analyzed. The analysis results show that the accuracy of elemental analysis between LIBS and traditional chemical methods is not much different, but the analysis time of LIBS method is shorter. Methods such as MLR, PLSR, and internal standard methods can improve the fit of the calibration curve and reduce the quantitative analysis error. By changing parameters such as laser energy and delay time, the spectral intensity can be enhanced to reduce the effects of matrix effects. In the process of elemental analysis, the effects of soil physical and chemical parameters should be considered comprehensively, and appropriate quantitative analysis methods should be adopted to improve the accuracy of the analysis results.

Download Full-text

Comparison of Near-Infrared and Laser-Induced Breakdown Spectroscopy for Determination of Magnesium Stearate in Pharmaceutical Powders and Solid Dosage Forms

Applied Spectroscopy ◽

10.1366/0003702053585354 ◽

2005 ◽

Vol 59 (3) ◽

pp. 340-347 ◽

Cited By ~ 29

Author(s):

Robert L. Green ◽

Mark D. Mowery ◽

Julie A. Good ◽

John P. Higgins ◽

Steven M. Arrivo ◽

...

Keyword(s):

Quantitative Analysis ◽

Near Infrared ◽

Matrix Effects ◽

Nir Spectroscopy ◽

Magnesium Stearate ◽

Laser Induced Breakdown Spectroscopy ◽

Breakdown Spectroscopy ◽

Laser Induced Breakdown ◽

Pharmaceutical Processing

Near-infrared (NIR) spectroscopy has become well established in both the pharmaceutical arena and other areas as a useful technique for rapid quantitative analysis of solid materials. Though laser-induced breakdown spectroscopy (LIBS) has not been widely applied in the pharmaceutical industry, the technique has been used for rapid quantitative analysis of solids in many other applications. One analysis amenable to each technique is the determination of magnesium stearate in solids during the lubrication blending unit operation of pharmaceutical processing. A comparative study of the utility of these two techniques for this application will be presented. Necessary sample preparations and the extent and type of matrix effects will be discussed. Additionally, it will be shown that NIR provides better accuracy and precision than LIBS with the experimental parameters used; however, LIBS showed superior selectivity as it was demonstrated to be more robust to sample matrix perturbations. Examples of blending applications will also be presented.

Download Full-text