scholarly journals Investigation of 2D WS2 nanosheet-reinforced tough DNA hydrogel as a biomedical scaffold: preparation and in vitro characterization

2022 ◽  
Author(s):  
Sayantani Basu ◽  
Aishik Chakraborty ◽  
Abdul-Rahman Imad Alkiswani ◽  
Yasmeen Shamiya ◽  
Arghya Paul
Keyword(s):  
Biomedical Applications ◽  
Natural Polymers ◽  
In Vitro Characterization ◽  
Dna Hydrogel

Hydrogels, prepared from natural polymers, are attractive biomaterials for diverse biomedical applications due to their excellent biocompatibility and bioactivity. However, the majority of conventional hydrogels are mechanically weak and unsuitable...

Chemical and in vitro characterization of epoxidized natural rubber blends for biomedical applications

2018 ◽  
Vol 25 (8) ◽  
Author(s):  
Nayrim Brizuela Guerra ◽  
Júlia Bünecker Cassel ◽  
Nicole Andréa Corbellini Henckes ◽  
Fernanda dos Santos de Oliveira ◽  
Elizabeth Obino Cirne-Lima ◽  
...  
Keyword(s):  
Natural Rubber ◽  
Biomedical Applications ◽  
Epoxidized Natural Rubber ◽  
Rubber Blends ◽  
In Vitro Characterization

Biological and biomedical applications of collagenous biomaterials

1990 ◽  
Vol 48 (3) ◽  
pp. 856-857
Author(s):  
Yasushi P. Kato ◽  
Michael G. Dunn ◽  
Frederick H. Silver ◽  
Arthur J. Wasserman
Keyword(s):  
Biomedical Applications ◽  
Soft Tissues ◽  
Collagen Fibers ◽  
Bone Collagen ◽  
Cover Slip ◽  
Fibroblast Migration ◽  
Cellular Expression ◽  
Defect Repair

Collagenous biomaterials have been used for growing cells in vitro as well as for augmentation and replacement of hard and soft tissues. The substratum used for culturing cells is implicated in the modulation of phenotypic cellular expression, cellular orientation and adhesion. Collagen may have a strong influence on these cellular parameters when used as a substrate in vitro. Clinically, collagen has many applications to wound healing including, skin and bone substitution, tendon, ligament, and nerve replacement. In this report we demonstrate two uses of collagen. First as a fiber to support fibroblast growth in vitro, and second as a demineralized bone/collagen sponge for radial bone defect repair in vivo.For the in vitro study, collagen fibers were prepared as described previously. Primary rat tendon fibroblasts (1° RTF) were isolated and cultured for 5 days on 1 X 15 mm sterile cover slips. Six to seven collagen fibers, were glued parallel to each other onto a circular cover slip (D=18mm) and the 1 X 15mm cover slip populated with 1° RTF was placed at the center perpendicular to the collagen fibers. Fibroblast migration from the 1 x 15mm cover slip onto and along the collagen fibers was measured daily using a phase contrast microscope (Olympus CK-2) with a calibrated eyepiece. Migratory rates for fibroblasts were determined from 36 fibers over 4 days.

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