Preparation of carbon-based metal organic frameworks modified molecularly imprinted polymers for selective recognition of bovine hemoglobin in biological samples

2022 ◽  
Author(s):  
Xue Chen ◽  
Jinyue Chai ◽  
Baodong Sun ◽  
Xue Yang ◽  
Feng Zhang ◽  
...  
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Metal Organic Framework ◽  
Selective Recognition ◽  
Template Molecule ◽  
Bovine Hemoglobin ◽  
Carbon Spheres ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Metal Organic ◽  
Carbon Based

In this study, the carbon-based Cu2+-immobilized metal-organic framework modified molecularly imprinted polymer (C@GI@Cu-MOFs@MIPs) adsorbent was prepared using bovine hemoglobin (BHb) as a template molecule with carbon spheres as carriers for...

Cholesterol-Imprinted Receptor Using Chitosan Derivative as the Precursor

2013 ◽  
Vol 699 ◽  
pp. 712-717
Author(s):  
Huai Min Guan ◽  
Yue Jin Tong ◽  
Jin Hua Zheng ◽  
Xiang Li
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Polar Solvent ◽  
Binding Capacity ◽  
Template Molecule ◽  
Chitosan Derivative ◽  
Amino Groups ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Selective Protection ◽  
Selection Of

Research has been focused on the development of molecularly imprinted polymers using a chitosan derivative as the precursor. An O-acyl chitosan was synthesized by the selective protection of amino groups of chitosan in MeSO3H and was cross-linked with glutaraldehyde in the presence/ absence of template molecule, cholesterol. The effect of the degree of the acyl substitution on the selection of precursor was investigated, regarding the solubility of chitosan derivative, interaction between the precursor and imprinted molecule, and degree of the cross-linking of precursor. The rebinding experiments indicated the significant recognition for cholesterol with imprinted polymer as compared with non-imprinted polymer. It was found that a good binding capacity of the imprinted polymer towards cholesterol could be achieved in a less-polar solvent. And the O-acyl chitosan-based molecularly imprinted polymer obtained displayed good recognition selectivity for cholesterol in comparison to similarly strctural analogue, cholesterol acetate.

scholarly journals MOLECULARLY IMPRINTED POLYMER NANOPARTICLES (MIP-NPs) APPLICATIONS IN ELECTROCHEMICAL SENSORS

2019 ◽  
pp. 1-6
Author(s):  
DIANE FAUZI ◽  
FEBRINA AMELIA SAPUTRI
Keyword(s):  
Molecularly Imprinted Polymers ◽  
High Stability ◽  
Electrochemical Sensors ◽  
Specific Binding ◽  
Environmental Contaminants ◽  
Polymer Nanoparticles ◽  
Selective Recognition ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Imprinted Polymers

Molecularly Imprinted Polymers (MIPs) is a polymer that binds together to form a specific binding site that is selective for certain analytes. Its high stability, its synthesize simplicity, and it can ease costs significantly make it was applied widely as a receptor instead of antibodies or enzymes. MIPs can be re-developed into MIPs nanoparticles (MIP-NPs) which have greater potential. MIPs use in electrochemical sensors have relevant applications in daily life and have been tested in human samples. Electrochemical sensors have been successfully functioned with MIP-NPs leading to real-time monitoring of drugs, pesticides, environmental contaminants, and secondary metabolites, as well as molecules with biological relevance. The aim of this review is to summarize the developments and applications of MIP-NPs as a selective recognition component in electrochemical sensors with special emphasis on their analytical applications.

Synthesis and Adsorption of Molecularly Imprinted Polymers of Dibutyl Phthalate in Food

2012 ◽  
Vol 549 ◽  
pp. 340-343 ◽  
Author(s):  
Jun Feng Zhu ◽  
Guang Hua Zhang ◽  
Ting Shang ◽  
Wei Xiong
Keyword(s):  
Silica Gel ◽  
Molecularly Imprinted Polymers ◽  
Dibutyl Phthalate ◽  
Silica Surface ◽  
Template Molecule ◽  
Imprinted Polymer ◽  
Adsorption Method ◽  
Adsorption Experiment ◽  
Molecularly Imprinted ◽  
Static Adsorption

In this paper, using environmental hormone dibutyl phthalate (DBP) in the contaminated foods as the template molecule, methacrylic acid (MAA) as functional monomer, ethylene glycol dimethacrylate ester (EDMA) as cross linking agent, the molecularly imprinted polymer (MIP) was prepared on the silica surface. The MIP was characterized by Fourier transform infrared spectroscopy (FTIR), thermogravimeric analysis (TGA) and automated surface area analyzer. The property of adsorption was tested using static adsorption method in water phrase. The results of FTIR indicate that there are recognition groups in the microspheres after imprinting. TGA illustrates the silica gel surface has been coated with a layer of polymer after the synthesis reaction. And the MIP can bear the high temperature of 200 °C. The thickness of the imprinted polymer coated on silica gel surface is estimated via the pore size data is about 1. 5nm. The result of static adsorption experiment shows that the saturated adsorption capacity of the MIP was 8.940mg/g.

Sign in / Sign up

Export Citation Format

Share Document