scholarly journals Enhanced penetrative siRNA delivery by a nanodiamond drug delivery platform against hepatocellular carcinoma 3D models

Nanoscale ◽  
2021 ◽  
Author(s):  
Jingru Xu ◽  
Mengjie Gu ◽  
Lissa Hooi ◽  
Tan Boon Toh ◽  
Dexter Kai Hao Thng ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Drug Delivery ◽  
Sirna Delivery ◽  
3D Models ◽  
Comprehensive Analysis ◽  
Gene Knockdown ◽  
Tumor Models ◽  
Anti Cancer ◽  
Delivery Platform

Comprehensive analysis of hepatocellular carcinoma 3D models revealed enhanced penetrative siRNA delivery by a nanodiamonds compared to liposomes. Nanodiamonds were able to improve siRNA's gene knockdown and anti-cancer effects in 3D tumor models.

Flexible assembly of targeting agents on porous magnetic nano-cargos by inclusion complexation for accurate drug delivery

2017 ◽  
Vol 1 (3) ◽  
pp. 521-529 ◽  
Author(s):  
Dian Li ◽  
Luyan Sun ◽  
Yuting Zhang ◽  
Meng Yu ◽  
Jia Guo ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Inclusion Complexation ◽  
Cancer Drug ◽  
Flexible Assembly ◽  
Anti Cancer ◽  
Delivery Platform

Porous magnetic nano-cargos with targeting folate molecules immobilized by inclusion complexation and large inner pores conjugated with anti-cancer drug doxorubicin have been demonstrated as a universal targeting drug delivery platform.

Synthesis, characterization, and formulation of poly-puerarin as a biodegradable and biosafe drug delivery platform for anti-cancer therapy

2019 ◽  
Vol 7 (5) ◽  
pp. 2152-2164 ◽  
Author(s):  
Tianqi Yi ◽  
Jun Huang ◽  
Xuewen Chen ◽  
Haiyun Xiong ◽  
Yang Kang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Tumour Therapy ◽  
Anti Cancer ◽  
Delivery Platform

Poly-puerarin, a novel biodegradable biomaterial as a drug delivery platform in anti-tumour therapy.

Enhanced hydroxyapatite nanorods formation on graphene oxide nanocomposite as a potential candidate for protein adsorption, pH controlled release and an effective drug delivery platform for cancer therapy

2017 ◽  
Vol 9 (2) ◽  
pp. 240-252 ◽  
Author(s):  
G. Bharath ◽  
B. Swarna Latha ◽  
Edreese H. Alsharaeh ◽  
P. Prakash ◽  
N. Ponpandian
Keyword(s):  
Drug Delivery ◽  
Graphene Oxide ◽  
Drug Loading ◽  
Creatine Phosphate ◽  
Cancer Drug ◽  
Potential Candidate ◽  
Anti Cancer ◽  
Delivery Platform ◽  
Phosphorus Source ◽  
Ph Dependent

Creatine phosphate used as a phosphorus source for synthesis of a HAp/GO nanocomposite toward protein/anti-cancer drug loading and selective pH dependent drug delivery platforms.

Hydrogel-clay Nanocomposites as Carriers for Controlled Release

2020 ◽  
Vol 27 (6) ◽  
pp. 919-954 ◽  
Author(s):  
Raluca Ianchis ◽  
Claudia Mihaela Ninciuleanu ◽  
Ioana Catalina Gifu ◽  
Elvira Alexandrescu ◽  
Cristina Lavinia Nistor ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Hybrid Materials ◽  
Pharmaceutical Formulations ◽  
Tree Of Life ◽  
Present Review ◽  
Clay Nanocomposites ◽  
Delivery Platform ◽  
Complex Hybrid

The present review aims to summarize the research efforts undertaken in the last few years in the development and testing of hydrogel-clay nanocomposites proposed as carriers for controlled release of diverse drugs. Their advantages, disadvantages and different compositions of polymers/biopolymers with diverse types of clays, as well as their interactions are discussed. Illustrative examples of studies regarding hydrogel-clay nanocomposites are detailed in order to underline the progressive researches on hydrogel-clay-drug pharmaceutical formulations able to respond to a series of demands for the most diverse applications. Brief descriptions of the different techniques used for the characterization of the obtained complex hybrid materials such as: swelling, TGA, DSC, FTIR, XRD, mechanical, SEM, TEM and biology tests, are also included. Enlightened by the presented data, we can suppose that hydrogel-clay nanocomposites will still be a challenging subject of global assiduous researches. We can dare to dream to an efficient drug delivery platform for the treatment of multiple affection concomitantly, these being undoubtedly like ”a tree of life” bearing different kinds of fruits and leaves proper for human healing.

Self-Assembled Nanocarriers Based on Amphiphilic Natural Polymers for Anti- Cancer Drug Delivery Applications

2018 ◽  
Vol 23 (35) ◽  
Author(s):  
Sally Sabra ◽  
Mona Abdelmoneem ◽  
Mahmoud Abdelwakil ◽  
Moustafa Taha Mabrouk ◽  
Doaa Anwar ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Drug ◽  
Natural Polymers ◽  
Anti Cancer ◽  
Drug Delivery Applications ◽  
Self Assembled ◽  
Cancer Drug Delivery
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