scholarly journals Recent Near-Infrared Light-Activated Nanomedicine toward Precision Cancer Therapy

Author(s):  
Xiaowei Luan ◽  
Yongchun Pan ◽  
Yanfeng Gao ◽  
Yujun Song

Light has witnessed the history of mankind and even the universe. It is of great significances to the life of human society, contributing to energy, agriculture, communication, and much more....

2020 ◽  
Vol 132 (47) ◽  
pp. 21218-21226
Author(s):  
Ruixue Song ◽  
Han Wang ◽  
Meng Zhang ◽  
Yanyan Liu ◽  
Xianfu Meng ◽  
...  

2017 ◽  
Vol 9 (34) ◽  
pp. 28185-28194 ◽  
Author(s):  
Yitong Wang ◽  
Ling Wang ◽  
Miaomiao Yan ◽  
Shuli Dong ◽  
Jingcheng Hao

ACS Nano ◽  
2017 ◽  
Vol 11 (12) ◽  
pp. 11898-11907 ◽  
Author(s):  
Bin Zheng ◽  
Hanjie Wang ◽  
Huizhuo Pan ◽  
Chao Liang ◽  
Wanying Ji ◽  
...  

2014 ◽  
Vol 07 (01) ◽  
pp. 1350037 ◽  
Author(s):  
YINGFENG DI ◽  
SISI CUI ◽  
YUEQING GU

A novel near-infrared light responsive microcapsule system, gold nanorod-covered DOX-loaded hollow CaCO 3 microcapsule ( AuNR -HM-DOX) is developed for cancer therapy. The hollow CaCO 3 microcapsules were prepared based on the self-assembly between chitosan and sodium alginate on CaCO 3 particles via layer-by-layer technique, and then covered with gold nanorods to obtain the microcapsule system. Upon near-infrared (NIR) irradiation, microcapsule with gold nanorods can convert the absorbed NIR light into heat. Meanwhile, doxorubicin (DOX), a chemotherapy drug, is loaded into the microcapsule system via electrostatic adsorption for combined photothermal therapy and chemotherapy. Properties of AuNR -HM-DOX including grain diameter, optical spectra were characterized. Confocal fluorescence imaging was performed to observe the morphology of the capsules and existence of DOX in the core, confirming the successful loading of DOX. The release of DOX from the capsules under continuous NIR irradiation was investigated to evaluate the temperature responsiveness of AuNR -HM-DOX. Results indicate that AuNR -HM-DOX microcapsules possess uniform particle size and high light responsiveness. The combination of chemical and physical therapy of AuNR -HM-DOX features great potential as an adjuvant therapeutic alternative material for combined cancer therapy.


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