Comparative studies of bile salts. 16-Deoxymyxinol, a second bile alcohol from hagfish
Keyword(s):
1. Material containing the less polar sulphate previously noticed in hagfish bile salts gave, after dioxan–trichloroacetic acid cleavage, 16-deoxymyxinol [3β,7α,-26(27)-trihydroxy-5α-cholestane]. 2. Anodic coupling of 3β-hydroxy-5β-cholanoic acid and the mixed half esters of dl-methylsuccinic acid, followed by lithium aluminium hydride reduction, yielded 3β,26(27)-dihydroxy-5β-cholestane. 3. 16-Deoxymyxinol, the third known bile alcohol having the 3β-hydroxy-5α-hydrogen configuration, poses again the question of how the 3β-hydroxyl group of cholesterol can be ‘retained’ in biosynthesis of primitive bile salts.
1967 ◽
Vol 8
(52)
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pp. 5261-5263
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1983 ◽
Vol 24
(13)
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pp. 1411-1414
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1986 ◽
Vol 251
(3)
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pp. R481-R491
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Keyword(s):
1973 ◽
Vol 56
(5)
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pp. 1646-1655
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1967 ◽
Vol 8
(11)
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pp. 971-974
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