The relationship between changes in lipid fuel availability and tissue fructose 2,6-bisphosphate concentrations and pyruvate dehydrogenase complex activities in the fed state
Keyword(s):
An elevated concentration of non-esterified fatty acids in the fed state elicited inhibition of cardiac, but not hepatic, pyruvate dehydrogenase complex (PDH). There was a modest decline in fructose 2,6-bisphosphate (Fru-2,6-P2) concentration in heart, and, to a lesser extent, in liver. Surgical stress decreased PDH activities and Fru-2,6-P2 concentrations in both heart and liver. Only the former response was abolished if postoperative lipolysis was inhibited. Surgery also decreased the [Fru-2,6-P2] in gastrocnemius: this response was abolished if lipolysis was inhibited.
1994 ◽
Vol 267
(4)
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pp. E528-E536
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1985 ◽
Vol 40
(11-12)
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pp. 917-918
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1983 ◽
Vol 15
(08)
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pp. 373-377
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1994 ◽
Vol 49
(7-8)
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pp. 421-426
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1993 ◽
Vol 265
(1)
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pp. E102-E107
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