Cerebrospinal Fluid Vasopressin and Oxytocin in Benign Intracranial Hypertension

1988 ◽  
Vol 74 (s18) ◽  
pp. 67P-67P
Author(s):  
JR Seckl ◽  
SL Lightman
Keyword(s):  
Cerebrospinal Fluid ◽  
Intracranial Hypertension ◽  
Benign Intracranial Hypertension

Benign intracranial hypertension associated with inhaled corticosteroids in a child with asthma

2021 ◽  
Vol 14 (5) ◽  
pp. e242455
Author(s):  
James Trayer ◽  
Declan O'Rourke ◽  
Lorraine Cassidy ◽  
Basil Elnazir
Keyword(s):  
Cerebrospinal Fluid ◽  
Intracranial Hypertension ◽  
Inhaled Corticosteroids ◽  
Benign Intracranial Hypertension ◽  
Inhaled Corticosteroid ◽  
Moderate Dose ◽  
Opening Pressure ◽  
Blurred Vision ◽  
Corticosteroid Dose ◽  
Steroid Side Effects

A 13-year-old male asthmatic presented to the general paediatric clinic with papilloedema identified following a check-up with his optician due to blurred vision. His asthma was well controlled on a moderate dose of inhaled corticosteroid and there had been no recent increase or decrease in the dose. A diagnosis of benign intracranial hypertension (BIH) was made based on a raised cerebrospinal fluid opening pressure, papilloedema, a normal neurological examination and normal neuroimaging. The only associated risk factor was his inhaled corticosteroids. He was commenced on acetazolamide and the inhaled corticosteroid dose was reduced, resulting in resolution of his papilloedema. This case serves to highlight that steroid side effects including BIH may occur at moderate doses of inhaled corticosteroids and that inhaled corticosteroid dose should be regularly reviewed and decreased to the lowest dose that maintains asthma control.

Significance of Empty Sella in Cerebrospinal Fluid Leaks

2003 ◽  
Vol 128 (1) ◽  
pp. 32-38 ◽  
Author(s):  
Rodney J. Schlosser ◽  
William E. Bolger
Keyword(s):  
Cerebrospinal Fluid ◽  
Intracranial Hypertension ◽  
Sella Turcica ◽  
Radiographic Finding ◽  
Empty Sella ◽  
Senior Author ◽  
Csf Leak ◽  
Benign Intracranial Hypertension ◽  
Cerebrospinal Fluid Leaks ◽  
Csf Leaks

OBJECTIVE: The role of elevated cerebrospinal fluid (CSF) pressures in the pathophysiology of various CSF leaks is not clear. Empty sella syndrome (ESS) is a radiographic finding that can be associated with elevated CSF pressures and may represent a radiographic indicator of intracranial hypertension. We present our experience with CSF leaks of various causes, the prevalence of ESS in the spontaneous and nonspontaneous categories, and the potential pathophysiology and unique management issues of the spontaneous CSF leak group. METHODS: We conducted a retrospective review of medical records, imaging studies, and surgical treatment of CSF leaks in patients treated by the senior author. RESULTS: Sixteen patients with spontaneous CSF leaks and 12 patients with nonspontaneous CSF leaks were surgically treated from 1996 through 2002. In the spontaneous group, 15 patients had complete imaging of the sella turcica. Ten had completely empty sellae and 5 had partially empty sellae, for a total of 100% (15 of 15). In the nonspontaneous group, 9 patients had complete imaging of the sella. Only 11% (1 of 9) had a partially empty sella and that was a congenital leak. Comparison of proportions between these 2 groups was significant ( P = 0.01). The spontaneous group consisted primarily of obese, middle-aged females (13 of 16 patients). CONCLUSION: Empty sella probably represents a sign of elevated intracranial pressure that leads to idiopathic, spontaneous CSF leaks. Spontaneous CSF leaks are strongly associated with the radiographic finding of an empty sella and are more common in obese females, similar to benign intracranial hypertension. This unique population may require more aggressive surgical and medical treatment to prevent recurrent or multiple leaks.

BENIGN INTRACRANIAL HYPERTENSION IN CHILDREN

PEDIATRICS ◽  
1967 ◽  
Vol 39 (2) ◽  
pp. 227-237
Author(s):  
Arthur Rose ◽  
Donald D. Matson
Keyword(s):  
Cerebrospinal Fluid ◽  
Intracranial Hypertension ◽  
Otitis Media ◽  
Viral Infections ◽  
Corticosteroid Treatment ◽  
Clinical Syndrome ◽  
Benign Intracranial Hypertension ◽  
Upper Respiratory Tract ◽  
Initial Manifestation ◽  
Tract Infections

The clinical features of 23 cases of benign intracranial hypertension occurring in childhood have been reviewed. Eight cases followed minor bacterial or viral infections, four cases occurred in association with head or neck injury, four cases occurred with otitis media, and one case followed sudden cessation of corticosteroid treatment. There were no apparent associated clinical factors in the remaining six cases. Benign intracranial hypertension thus emerges as a clinical syndrome of varied etiology, generally with a short course, good prognosis, little tendency to recurrence, and only rarely requiring surgical intervention. Clinical evidence suggests that, in addition to otitis media, cerebral venous thrombosis may, in certain circumstances, follow head injury, trauma to the jugular vein, and thrombosis in the pterygoid venous plexus. Therefore, it is suggested that complete visualization of the venous cerebral circulation should be attempted in the investigation of patients with benign intracranial hypertension. In view of the occurrence of the syndrome following gastroenteritis, upper respiratory tract infections, and chickenpox, diagnostic virological studies, including culture of cerebrospinal fluid, are of special interest. Other precipitating causes of this clinical syndrome are discussed. The occurrence of benign intracranial hypertension as an initial manifestation of two well defined endocrine abnormalities is described. It is possible in the future that systematic endocrine study of patients, particularly pre-pubertal females, will reveal other hormonal defects. It appears probable that transient generalized cerebral edema of any type may be responsible for the occurrence of this syndrome. The elucidation of its pathophysiology will probably have to wait more accurate and safe methods of clinical measurement of intra- and extra-cellular fluid shifts within the brain, as well as more reliable understanding of cerebrospinal fluid and cerebral blood flow alterations.

Benign intracranial hypertension with spinal and radicular pain

1982 ◽  
Vol 57 (6) ◽  
pp. 833-836 ◽  
Author(s):  
Marco Bortoluzzi ◽  
Leonardo Di Lauro ◽  
Giovanni Marini
Keyword(s):  
Cerebrospinal Fluid ◽  
Serum Albumin ◽  
Intracranial Hypertension ◽  
Spinal Pain ◽  
Radicular Pain ◽  
Benign Intracranial Hypertension ◽  
Csf Flow ◽  
Content Type ◽  
Csf Absorption ◽  
Fine Print

✓ A case of benign intracranial hypertension with polyradiculopathy and spinal pain is reported. Radioactive iodinated serum albumin (RISA) cisternography demonstrated the absence of cerebrospinal fluid (CSF) flow into the intracranial cisterns, and gave evidence of CSF absorption through the spinal arachnoid villi.

Cerebrospinal fluid vasopressin in benign intracranial hypertension

Neurology ◽  
1982 ◽  
Vol 32 (11) ◽  
pp. 1255-1255 ◽  
Author(s):  
P. S. Sorensen ◽  
M. Hammer ◽  
F. Gjerris
Keyword(s):  
Cerebrospinal Fluid ◽  
Intracranial Hypertension ◽  
Benign Intracranial Hypertension

Experimental effects of steroids and steroid withdrawal on cerebrospinal fluid absorption

1975 ◽  
Vol 42 (6) ◽  
pp. 690-695 ◽  
Author(s):  
Ian Johnston ◽  
David L. Gilday ◽  
E. Bruce Hendrick
Keyword(s):  
Cerebrospinal Fluid ◽  
Intracranial Hypertension ◽  
Chronic Administration ◽  
Benign Intracranial Hypertension ◽  
Steroid Withdrawal ◽  
Content Type ◽  
Cisterna Magna ◽  
Sagittal Sinus ◽  
Ringer’S Lactate ◽  
Csf Absorption

✓ The authors studied the effects on cerebrospinal fluid (CSF) absorption of chronic administration and acute withdrawal of steroids in dogs. CSF absorption was measured by determining the amount of isotope (indium 111DTPA) recovered over a 4-hour period after injection into the cisterna magna. Resistance to CSF absorption was estimated by determining rates of flow of Ringer's lactate infusion into the cisterna magna over a range of pressure gradients between CSF and sagittal sinus. Steroid withdrawal was associated with a marked reduction in CSF absorption and an increase in resistance to CSF flow. Dogs on steroids also showed reduced CSF absorption although the reduction was not statistically significant when compared with controls. The results are discussed in terms of possible mechanisms of action of steroids on CSF absorption, the etiology of the benign intracranial hypertension syndrome and the use of steroids in the control of intracranial hypertension.

Cerebrospinal fluid diversion in the treatment of benign intracranial hypertension

1988 ◽  
Vol 69 (2) ◽  
pp. 195-202 ◽  
Author(s):  
Ian Johnston ◽  
Michael Besser ◽  
Michael K. Morgan
Keyword(s):  
Cerebrospinal Fluid ◽  
Intracranial Hypertension ◽  
Primary Treatment ◽  
Consecutive Series ◽  
Complication Rates ◽  
Benign Intracranial Hypertension ◽  
Content Type ◽  
Cerebrospinal Fluid Diversion ◽  
Cerebrospinal Fluid Shunting ◽  
Shunt Dependence

✓ Thirty-six patients from a consecutive series of 41 patients with benign intracranial hypertension (BIH) were treated by cerebrospinal fluid shunting. In 12 patients this was selected as the primary treatment due to the severe deterioration of vision or concern regarding the possible adverse effects of steroids; all 12 patients showed rapid and complete resolution of the disease, although eight patients still have a shunt in place. In 24 patients a shunt was inserted when other forms of treatment failed; all of these patients showed rapid resolution of the condition, although 20 patients still have a shunt in place. Three patients had the shunt removed without sequelae, and one patient in whom the shunt was removed because of low-pressure symptoms remains symptomatic with persistent papilledema (over 6 years). The percutaneous lumboperitoneal (LP) shunt was associated with the lowest revision and complication rates. Cisternal shunting to either the atrium or pleural cavity was next most effective, whereas valved LP shunts inserted via a laminectomy were least effective; ventricular shunts were used in only two cases. Shunting is therefore very effective in the treatment of BIH, but the significant complication rate and the possibility of inducing shunt dependence must be recognized.

scholarly journals Optic fenestration in benign intracranial hypertension: case report

2020 ◽  
Vol 6 (12) ◽  
pp. 2289
Author(s):  
Manish Munjal ◽  
Monika Singla ◽  
Sahil Goel ◽  
Porshia Rishi ◽  
Nitika Tuli ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Case Report ◽  
Intracranial Hypertension ◽  
Pseudotumor Cerebri ◽  
Fluid Composition ◽  
Benign Intracranial Hypertension ◽  
Raised Intracranial Pressure ◽  
Visual Effects ◽  
Emergency Intervention ◽  
Diamond Burr

<p class="abstract"><span lang="EN-US">Condition of raised intracranial pressure without any mass lesion and normal cerebrospinal fluid composition is termed as idiopathic intracranial hypertension or pseudotumor cerebri. Raised intracranial tension with visual effects was treated by trans-sphenoidal optic fenestration as an emergency intervention to salvage the vision. The lamina papyracea on either side was lifted off the orbital periosteum and thick bone of the ethmoid sphenoidal junction was drilled with a diamond burr to thin it and elevate the bone covering the optic nerve.</span></p>

Sign in / Sign up

Export Citation Format

Share Document