Impact of Changes in Respiratory Frequency and Posture on Power Spectral Analysis of Heart Rate and Systolic Blood Pressure Variability in Normal Subjects and Patients with Heart Failure

1996 ◽  
Vol 91 (1) ◽  
pp. 35-43 ◽  
Author(s):  
John E. Sanderson ◽  
Leata Y. C. Yeung ◽  
Dickens T. K. Yeung ◽  
Richard L. C. Kay ◽  
Brian Tomlinson ◽  
...  
Keyword(s):  
Heart Failure ◽  
Blood Pressure ◽  
Heart Rate ◽  
Spectral Analysis ◽  
High Frequency ◽  
Low Frequency ◽  
Power Spectral Analysis ◽  
Normal Subjects ◽  
Power Spectral ◽  
Patients With Heart Failure

1. Autonomic dysfunction is a major feature of congestive cardiac failure and may have an important role in determining progression and prognosis. The low-frequency/high-frequency ratio derived from power spectral analysis of heart rate variability has been proposed as a non-invasive method to assess sympatho-vagal balance. However, the effects of different respiratory rates or posture are rarely accounted for, but may be relevant in patients with heart failure in whom clinical improvement is accompanied by a fall in respiratory rate and an increased proportion of the day in the upright position. 2. We have assessed the effect of controlled respiration at different rates (10, 15, 20 breaths/min or 0.17, 0.25 and 0.33 Hz), while supine and standing, on power spectral analysis of heart rate and blood pressure variability in 11 patients with heart failure and 10 normal subjects. 3. Heart rate variance and low-frequency power (normalized units) were reduced in patients with heart failure (absent in six). During controlled breathing while supine, the power of the high-frequency component was significantly greater at 10 breaths/min than at 20 breaths/min in patients with heart failure, whether expressed in absolute units (P = 0.005) or percentage of total power (P = 0.03). 4. On standing, controlled breathing in patients with heart failure produced less change in high-frequency power (P = 0.054), but the low-frequency/high-frequency ratio at lower respiratory rates was reduced (P = 0.05). In normal subjects, as expected, respiratory rate had a highly significant effect on high-frequency power. Also, in normal subjects there was the expected increase in heart rate low-frequency power (P = 0.04) moving from supine to standing with an increase in the low-frequency/high-frequency ratio (P = 0.003), while in the patients with heart failure this was absent, reflecting blunted cardiovascular reflexes. 5. Systolic blood pressure low- and high-frequency components and their ratio were significantly affected by respiration (P > 0.03) and change in posture (P > 0.03) in both patients with heart failure and normal subjects, with a significant increase in the low-frequency/high-frequency ratio (P = 0.03) on standing in patients with heart failure, indicating that autonomic modulation of blood pressure is still operating in heart failure. 6. Thus, respiratory rate and changes in posture have a significant effect on measurements derived from spectral analysis of heart rate and blood pressure variability. Studies that use power spectral analysis as a measure of sympatho-vagal balance should control for these variables.

scholarly journals Power spectral analysis of heart rate variability in Bangladeshi healthy male and female

2016 ◽  
Vol 43 (3) ◽  
pp. 146-150
Author(s):  
Qazi Farzana Akhter ◽  
Qazi Shamima Akhter ◽  
Farhana Rahman ◽  
Sybilla Ferdousi ◽  
Susmita Sinha
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Spectral Analysis ◽  
High Frequency ◽  
Low Frequency ◽  
Power Spectral Analysis ◽  
Autonomic Nerve ◽  
Age Group ◽  
Power Spectral

Heart rate variability (HRV) has been considered as an indicator of autonomic nerve function status. We aimed to find out the reference values of heart rate variability by power spectral analysis in our healthy population of both sex. This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka from the period of July 2012 to June 2013. For this, 180 subjects were selected with the age ranging from 15-60 years. All the study subjects were divided into 3 different groups according to age (Group A: 15-30 years; Group B: 31-45 years; Group C: 46-60 years). Each group contained 60 subjects of which 30 were male and 30 were female. Analysis of HRV parameters were done in Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka. Systolic blood pressure, diastolic blood pressure, low frequency normalized unit, low frequency / high frequency ratio were significantly higher in male than female. Again high frequency power, high frequency normalized unit were significantly higher in female than male of same age group. This study concludes that male showed higher cardiac sympathetic activities while female showed higher cardiac parasympathetic activities in different age groups.Bangladesh Med J. 2014 Sep; 43 (3): 146-150

Physiology and Pathophysiology of Heart Rate and Blood Pressure Variability in Humans: Is Power Spectral Analysis Largely An Index of Baroreflex Gain?

1995 ◽  
Vol 88 (1) ◽  
pp. 103-109 ◽  
Author(s):  
Peter Sleight ◽  
Maria Teresa La Rovere ◽  
Andrea Mortara ◽  
Gianni Pinna ◽  
Roberto Maestri ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Spectral Analysis ◽  
High Frequency ◽  
Blood Pressure Variability ◽  
Baroreflex Sensitivity ◽  
Low Frequency ◽  
Power Spectral Analysis ◽  
Autonomic Balance ◽  
Baroreflex Control ◽  
Power Spectral

1. It is often assumed that the power in the low-(around 0.10 Hz) and high-frequency (around 0.25 Hz) bands obtained by power spectral analysis of cardiovascular variables reflects vagal and sympathetic tone respectively. An alternative model attributes the low-frequency band to a resonance in the control system that is produced by the inefficiently slow time constant of the reflex response to beat-to-beat changes in blood pressure effected by the sympathetic (with or without the parasympathetic) arm(s) of the baroreflex (De Boer model). 2. We have applied the De Boer model of circulatory variability to patients with varying baroreflex sensitivity and one normal subject, and have shown that the main differences in spectral power (for both low and high frequency) between and within subjects are caused by changes in the arterial baroreflex gain, particularly for vagal control of heart rate (R—R interval) and left ventricular stroke output. We have computed the power spectrum at rest and during neck suction (to stimulate carotid baroreceptors). We stimulated the baroreceptors at two frequencies (0.1 and 0.2 Hz), which were both distinct from the controlled respiration rate (0.25 Hz), in both normal subjects and heart failure patients with either sensitive or poor baroreflex control. 3. The data broadly confirm the De Boer model. The low-frequency (0.1 Hz) peak in either R—R or blood pressure variability) was spontaneously generated only if the baroreflex control of the autonomic outflow was relatively intact. With a large stimulus to the carotid baroreceptor it was possible to influence the low-frequency R—R but not low-frequency blood pressure variability. This implies that it is too simplistic to use power spectral analysis as a simple measure of autonomic balance its underlying modulation is more complex than generally believed. 4. It may be that power spectral analysis is more a sensitive indicator of baroreflex control, particularly of vagal control, than direct evidence of autonomic balance. of course, there is often a correlation between the gain of the reflex and the autonomic balance of vagus and sympathetic. These considerations may help our understanding of some conditions, such as exercise or heart failure, when the power spectral analysis method fails to identify increased sympathetic discharge; this failure may partly be explained by the decrease in baroreflex sensitivity which occurs in these two conditions.

Power spectral analysis of heart rate and blood pressure variability in anaesthetized dogs

1992 ◽  
Vol 146 (2) ◽  
pp. 155-164 ◽  
Author(s):  
A. E. HEDMAN ◽  
J. E. K. HARTIKAINEN ◽  
K. U. O. TAHVANAINEN ◽  
M. O. K. HAKUMÄKI
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Spectral Analysis ◽  
Blood Pressure Variability ◽  
Power Spectral Analysis ◽  
Power Spectral

Hyperinsulinemia produces cardiac vagal withdrawal and nonuniform sympathetic activation in normal subjects

1999 ◽  
Vol 276 (1) ◽  
pp. R178-R183 ◽  
Author(s):  
Philippe Van De Borne ◽  
Martin Hausberg ◽  
Robert P. Hoffman ◽  
Allyn L. Mark ◽  
Erling A. Anderson
Keyword(s):  
High Frequency ◽  
Sympathetic Activity ◽  
Sympathetic Nerve Activity ◽  
Muscle Sympathetic Nerve Activity ◽  
Low Frequency ◽  
Power Spectral Analysis ◽  
Normal Subjects ◽  
Power Spectral ◽  
Low Frequency Variability ◽  
High Frequency Variability

The exact mechanisms for the decrease in R-R interval (RRI) during acute physiological hyperinsulinemia with euglycemia are unknown. Power spectral analysis of RRI and microneurographic recordings of muscle sympathetic nerve activity (MSNA) in 16 normal subjects provided markers of autonomic control during 90-min hyperinsulinemic/euglycemic clamps. By infusing propranolol and insulin ( n = 6 subjects), we also explored the contribution of heightened cardiac sympathetic activity to the insulin-induced decrease in RRI. Slight decreases in RRI ( P < 0.001) induced by sevenfold increases in plasma insulin could not be suppressed by propranolol. Insulin increased MSNA by more than twofold ( P < 0.001), decreased the high-frequency variability of RRI ( P< 0.01), but did not affect the absolute low-frequency variability of RRI. These results suggest that reductions in cardiac vagal tone and modulation contribute at least in part to the reduction in RRI during hyperinsulinemia. Moreover, more than twofold increases in MSNA occurring concurrently with a slight and not purely sympathetically mediated tachycardia suggest regionally nonuniform increases in sympathetic activity during hyperinsulinemia in humans.

scholarly journals Power Spectral Analysis of Spontaneous Blood Pressure and Heart Rate Variability in Elderly Hypertensives.

1996 ◽  
Vol 19 (1) ◽  
pp. 9-16 ◽  
Author(s):  
Tadashi Aono ◽  
Takayuki Sato ◽  
Masanori Nishinaga ◽  
Akiko Kawamoto ◽  
Toshio Ozawa
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Spectral Analysis ◽  
Power Spectral Analysis ◽  
Power Spectral ◽  
Elderly Hypertensives

Abnormal passive head-up tilt test in subjects with symptoms of anxiety power spectral analysis study of heart rate and blood pressure

1997 ◽  
Vol 60 (2) ◽  
pp. 121-131 ◽  
Author(s):  
Gianfranco Piccirillo ◽  
Santagada Elvira ◽  
Carmela Bucca ◽  
Emanuela Viola ◽  
Mauro Cacciafesta ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Spectral Analysis ◽  
Power Spectral Analysis ◽  
Tilt Test ◽  
Analysis Study ◽  
Power Spectral ◽  
Head Up Tilt ◽  
Head Up Tilt Test

Power Spectral Analysis of Heart Rate and Diastolic Blood Pressure Variability in Migraine with and Without Aura

Cephalalgia ◽  
1997 ◽  
Vol 17 (7) ◽  
pp. 756-760 ◽  
Author(s):  
G Pierangeli ◽  
P Parchi ◽  
G Barletta ◽  
M Chiogna ◽  
E Lugaresi ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Spectral Analysis ◽  
Diastolic Blood Pressure ◽  
Blood Pressure Variability ◽  
Power Spectral Analysis ◽  
Cardiovascular Responses ◽  
Valsalva Manoeuvre ◽  
Cardiovascular Reflexes ◽  
Power Spectral

Autonomic function in migraineurs during headache-free periods was studied by means of cardiovascular reflexes and power spectral analysis of heart rate and diastolic blood pressure variability. We examined 56 patients: 37 suffering from migraine without aura and 19 from migraine with aura. Cardiovascular responses to the tilt test and Valsalva manoeuvre showed a normal function of the overall baroreceptor reflex arc. Normal heart rate responses to valsalva manoeuvre and deep breathing suggested an intact parasympathetic function. Power spectral analysis of both heart rate and diastolic blood pressure variability in basal conditions and during orthostatic test showed similar sympathovagal interactions modulating cardiovascular control in migraine patients and in controls.

scholarly journals Cooling-Evoked Hemodynamic Perturbations Facilitate Sympathetic Activity with Subsequent Myogenic Vascular Oscillations via Alpha2-Adrenergic Receptors

2017 ◽  
pp. 449-457 ◽  
Author(s):  
Y.-H. LIN ◽  
Y.-P. LIU ◽  
Y.-C. LIN ◽  
P.-L. LEE ◽  
C.-S. TUNG
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Pressor Response ◽  
Low Frequency ◽  
Power Spectral Analysis ◽  
Sprague Dawley ◽  
Cold Stimulation ◽  
Very Low Frequency ◽  
Power Spectral ◽  
Sprague Dawley Rats

This study extends our previous work by examining the effects of alpha2-adrenoceptors under cold stimulation involving the increase of myogenic vascular oscillations as increases of very-low-frequency and low-frequency of the blood pressure variability. Forty-eight adult male Sprague-Dawley rats were randomly divided into four groups: vehicle; yohimbine; hexamethonium+yohimbine; guanethidine+yohimbine. Systolic blood pressure, heart rate, power spectral analysis of spontaneous blood pressure and heart rate variability and spectral coherence at very-low-frequency (0.02 to 0.2 Hz), low-frequency (0.2 to 0.6 Hz), and high-frequency (0.6 to 3.0 Hz) regions were monitored using telemetry. Key findings are as follows: 1) Cooling-induced pressor response was attenuated by yohimbine and further attenuated by hexamethonium+yohimbine and guanethidine+yohimbine, 2) Cooling-induced tachycardia response of yohimbine was attenuated by hexame-thonium+yohimbine and guanethidine+yohimbine, 3) Different patterns of power spectrum reaction and coherence value compared hexamethonium+yohimbine and guanethi-dine+yohimbine to yohimbine alone under cold stimulation. The results suggest that sympathetic activation of the postsynaptic alpha2-adrenoceptors causes vasoconstriction and heightening myogenic vascular oscillations, in turn, may increase blood flow to prevent tissue damage under stressful cooling challenge.

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