miR-296/Scribble axis is deregulated in human breast cancer and miR-296 restoration reduces tumour growth in vivo
Keyword(s):
miR-296-5p is a nodal miRNA deregulated in diverse human cancers. In the present study we show that miR-296-5p and its target Scribble play a role in breast carcinogenesis and metastatic dissemination. Furthermore, an miR-296-5p-based therapeutic approach hampers breast cancer tumour growth in vivo.
1998 ◽
Vol 55
(6)
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pp. 841-851
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1987 ◽
Vol 74
(3)
◽
pp. 227-229
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