miR-296/Scribble axis is deregulated in human breast cancer and miR-296 restoration reduces tumour growth in vivo

2014 ◽  
Vol 127 (4) ◽  
pp. 233-242 ◽  
Author(s):  
Federica Savi ◽  
Irene Forno ◽  
Alice Faversani ◽  
Andrea Luciani ◽  
Sarah Caldiera ◽  
...  

miR-296-5p is a nodal miRNA deregulated in diverse human cancers. In the present study we show that miR-296-5p and its target Scribble play a role in breast carcinogenesis and metastatic dissemination. Furthermore, an miR-296-5p-based therapeutic approach hampers breast cancer tumour growth in vivo.

1998 ◽  
Vol 55 (6) ◽  
pp. 841-851 ◽  
Author(s):  
R.Jeffrey Baumann ◽  
Tammy L. Bush ◽  
Doreen E. Cross-Doersen ◽  
Elizabeth A. Cashman ◽  
Paul S. Wright ◽  
...  

Author(s):  
Paul A. Bunn ◽  
David G. Dienhart ◽  
Raymond F. Schmelter ◽  
James L. Lear ◽  
Gary Miller ◽  
...  

2014 ◽  
Vol 32 (4) ◽  
pp. 1385-1394 ◽  
Author(s):  
YUICHI KINOSHITA ◽  
KATSUHIKO YOSHIZAWA ◽  
KEI HAMAZAKI ◽  
YUKO EMOTO ◽  
TAKASHI YURI ◽  
...  

Oncotarget ◽  
2017 ◽  
Vol 9 (4) ◽  
pp. 4593-4606 ◽  
Author(s):  
Ka-Wai Tam ◽  
Chi-Tang Ho ◽  
Shih-Hsin Tu ◽  
Wen-Jui Lee ◽  
Ching-Shui Huang ◽  
...  

2005 ◽  
Vol 22 (2) ◽  
pp. 129-138 ◽  
Author(s):  
M. Waheed Roomi ◽  
Vadim Ivanov ◽  
Tatiana Kalinovsky ◽  
Aleksandra Niedzwiecki ◽  
Matthias Rath

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