scholarly journals Inhibition of calcium oxalate crystal growth and aggregation by prothrombin and its fragments in vitro . Relationship between protein structure and inhibitory activity

1999 ◽  
Vol 263 (1) ◽  
pp. 50-56 ◽  
Author(s):  
Phulwinder K. Grover ◽  
Rosemary L. Ryall
Keyword(s):  
Crystal Growth ◽  
Protein Structure ◽  
Calcium Oxalate ◽  
Inhibitory Activity ◽  
Calcium Oxalate Crystal

scholarly journals FKBP-12 Exhibits an Inhibitory Activity on Calcium Oxalate Crystal Growth in Vitro

2002 ◽  
Vol 17 (1) ◽  
pp. 41 ◽  
Author(s):  
In Sook Han ◽  
Yasushi Nakagawa ◽  
Jong Wook Park ◽  
Min Ho Suh ◽  
Sung IL Suh ◽  
...  
Keyword(s):  
Crystal Growth ◽  
Calcium Oxalate ◽  
Inhibitory Activity ◽  
Calcium Oxalate Crystal

scholarly journals ISOLATION OF URINARY HEPARAN SULFATE AND CHONDROITIN SULFATE AND THEIR INHIBITORY ACTIVITY OF CALCIUM OXALATE CRYSTAL GROWTH

1991 ◽  
Vol 82 (3) ◽  
pp. 405-411 ◽  
Author(s):  
Hidenobu Iwata ◽  
Takashi Terado ◽  
Masahiro Kin ◽  
Shunji Nishio ◽  
Masafumi Takeuchi ◽  
...  
Keyword(s):  
Crystal Growth ◽  
Calcium Oxalate ◽  
Heparan Sulfate ◽  
Chondroitin Sulfate ◽  
Inhibitory Activity ◽  
Calcium Oxalate Crystal

scholarly journals IN VITRO STUDIES ON CALCIUM OXALATE CRYSTAL GROWTH INHIBITION OF STROBILANTHES CRISPUS EXTRACTS

2015 ◽  
Vol 3 (1) ◽  
pp. 8
Author(s):  
Afrizal Itam ◽  
Zhari Ismail ◽  
Amin Malik Shah Abdul Majid
Keyword(s):  
Crystal Growth ◽  
Calcium Oxalate ◽  
Sodium Citrate ◽  
Water Extract ◽  
Positive Control ◽  
Calcium Oxalate Crystal ◽  
Strobilanthes Crispus ◽  
Crystal Growth Inhibition ◽  
Acetone Extracts

 ABSTRACT Strobilanthes crispus L. (Acanthaceae) has been used locally in traditional medicine for kidney stone and related diseases. These plant extracts have the ability to inhibit the calcium oxalate crystal growth, where the ability of water extract is higher than those of the 70% acetone, methanol and acetone extracts. The ability to inhibit the calcium oxalate crystal growth of these extracts is lower than that of sodium citrate as positive control. Keywords: Strobilanthes crispus, Acanthaceae, crystal inhibition, calcium oxalate

Inhibitory Activity of Human Urine on Calcium Oxalate Crystal Growth: Effects of Sodium Urate and Uric Acid

1982 ◽  
Vol 62 (5) ◽  
pp. 509-514 ◽  
Author(s):  
B. Fellström ◽  
U. Backman ◽  
B. G. Danielson ◽  
K. Holmgren ◽  
S. Ljunghall ◽  
...  
Keyword(s):  
Uric Acid ◽  
Crystal Growth ◽  
Calcium Oxalate ◽  
Inhibitory Activity ◽  
Calcium Oxalate Crystal ◽  
Molecular Fraction ◽  
Almost All ◽  
Pronounced Reduction ◽  
Sodium Urate ◽  
Urate Crystals

1. Freshly voided urine from healthy subjects was pooled and ultrafiltered (10 000 daltons). The ultrafiltrable and the macromolecular portions were preincubated with calcium oxalate, uric acid and sodium urate crystals and the effects on the inhibitory activity of calcium oxalate crystal growth assessed by monitoring the disappearance of [14C]oxalate from the solution. 2. The inhibitory activity of the ultrafiltrate was higher than that of the urinary macro-molecular fraction. Both uninhibited and inhibited crystal growth processes followed second-order kinetics. 3. Calcium oxalate crystals adsorbed almost all the urinary macromolecular inhibitors whereas sodium urate or uric acid crystals adsorbed only 10–20%. 4. In the presence of a metastable solution of calcium oxalate, the incubation of the urinary macromolecular fraction with sodium urate crystals caused a pronounced reduction in the inhibitory activity. A similar effect was seen with uric acid crystals, but to a lesser degree. 5. We conclude that the effect of sodium urate or uric acid crystals alone on naturally occurring urinary macromolecular inhibitors of calcium oxalate crystal growth is weak, but that in the presence of metastable calcium oxalate this is greatly enhanced. A substantial adsorption of the inhibitors on to the crystals is suggested, possibly secondary to epitaxial growth of calcium oxalate on the surface of the urate crystals.

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