Executive function in traumatic brain injury and obsessive-compulsive disorder: An overlap?

2001 ◽  
Vol 55 (2) ◽  
pp. 83-87 ◽  
Author(s):  
Rudolf Coetzer ◽  
Dan J. Stein ◽  
Pieter L. Du Toit
CNS Spectrums ◽  
2015 ◽  
Vol 20 (5) ◽  
pp. 463-465 ◽  
Author(s):  
Michelle Rydon-Grange ◽  
Rudi Coetzer

In addition to the well-known cognitive impairment following traumatic brain injury (TBI), neuropsychiatric sequelae are often reported as well. Although not the most common neuropsychiatric consequence of TBI, obsessive-compulsive disorder (OCD) has been associated with TBI. However, diagnosing new onset OCD secondary to TBI is complicated by the potential for cognitive impairment secondary to TBI masquerading as OCD. In particular, memory difficulties and executive dysfunction may be confused as representing obsessions and compulsions. Research in this area, which could guide clinical practice, remains limited. In addition to using Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V) criteria, neuropsychological testing and collateral interviews may help clinicians when considering differential diagnoses in this complex area of neuropsychiatry.


Neurocase ◽  
2013 ◽  
Vol 19 (4) ◽  
pp. 390-400 ◽  
Author(s):  
Helene Hofer ◽  
Susanna Frigerio ◽  
Eveline Frischknecht ◽  
Daniel Gassmann ◽  
Klemens Gutbrod ◽  
...  

2020 ◽  
Author(s):  
Sofia Persson ◽  
Alan Yates ◽  
Klaus Kessler ◽  
Ben Harkin

Even though memory performance is a commonly researched aspect of Obsessive-Compulsive Disorder (OCD), a coherent and unified explanation of the role of specific cognitive factors has remained elusive. To address this, the present meta-analysis examined the predictive validity of Harkin and Kessler’s (2011) Executive Function (E), Binding Complexity (B) and Memory Load (L) Classification System with regards to affected vs. unaffected memory performance in OCD. We employed a multi-level meta-analytic approach (Viechtbauer, 2010) to accommodate the interdependent nature of the EBL model and interdependency of effect sizes (305 effect sizes from 144 studies, including 4424 OCD patients). Results revealed that the EBL model predicted memory performance, i.e., as EBL demand increases, those with OCD performed progressively worse on memory tasks. Executive function was the driving mechanism behind the EBL’s impact on OCD memory performance and negated effect size differences between visual and verbal tasks in those with OCD. Comparisons of sub-task effect sizes were also generally in accord with the cognitive parameters of the EBL taxonomy. We conclude that standardised coding of tasks along individual cognitive dimensions and multi-level meta-analyses provides a new approach to examine multi-dimensional models of memory and cognitive performance in OCD and other disorders.


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