n-3 polyunsaturated fatty acid supplementation, monocyte adhesion molecule expression and pro-inflammatory mediators in Type 2 diabetes mellitus

2001 ◽  
Vol 18 (1) ◽  
pp. 51-58 ◽  
Author(s):  
M. J. Sampson ◽  
I. R. Davies ◽  
J. C. Brown ◽  
V. Morgan ◽  
T. Richardson ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Fatty Acid ◽  
Adhesion Molecule ◽  
Inflammatory Mediators ◽  
Adhesion Molecule Expression ◽  
Monocyte Adhesion ◽  
Fatty Acid Supplementation

Type 2 diabetes mellitus is associated with impaired cytokine response and adhesion molecule expression in human endotoxemia

2010 ◽  
Vol 36 (9) ◽  
pp. 1548-1555 ◽  
Author(s):  
Anne Sofie Andreasen ◽  
Theis Pedersen-Skovsgaard ◽  
Ronan M. G. Berg ◽  
Kira Dynnes Svendsen ◽  
Bo Feldt-Rasmussen ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Adhesion Molecule ◽  
Cytokine Response ◽  
Adhesion Molecule Expression ◽  
Human Endotoxemia

scholarly journals Effect of n-3 Polyunsaturated Fatty Acid Supplementation on Metabolic and Inflammatory Biomarkers in Type 2 Diabetes Mellitus Patients

Nutrients ◽  
2017 ◽  
Vol 9 (6) ◽  
pp. 573 ◽  
Author(s):  
M. Gorety Jacobo-Cejudo ◽  
Roxana Valdés-Ramos ◽  
Ana L. Guadarrama-López ◽  
Rosa-Virgen Pardo-Morales ◽  
Beatriz E. Martínez-Carrillo ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acid ◽  
Inflammatory Biomarkers ◽  
Fatty Acid Supplementation ◽  
Acid Supplementation

scholarly journals The effect of omega 3 fatty acid supplementation on HbA1c serum in geriatric patients with type 2 diabetes mellitus: an evidence-based case report

2020 ◽  
Vol 4 (1) ◽  
pp. 26
Author(s):  
Marvin Marino ◽  
Lily Indriani Octovia
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Case Report ◽  
Fatty Acid ◽  
Evidence Based ◽  
Omega 3 ◽  
Fatty Acid Supplementation ◽  
Omega 3 Fatty Acid

Background: The prevalence of diabetes mellitus as a non-communicable diseases increase annually. The global prevalence doubled from 4.7% to 8.5% in 1980 until 2016. Insulin resistance is the primary cause of type 2 diabetes mellitus. Polyunsaturated fatty acid has a contribution to membrane fluidity as well as the cell signaling system. The result of studies about the correlation between Omega-3 supplementation and blood glucose control in patients with type 2 diabetes is still inconsistent. Meanwhile, we considered to give a 86 year old woman with an uncontrolled type 2 diabetes omega-3 fatty acid supplementation for controlling her blood glucose. Thus, we performed an evidence-based case report to respond this problem.Objectives: To observe the effect of omega-3 supplementation on glycated hemoglobin (HbA1c) serum of type 2 diabetes mellitus patients. Methods: Electronic literature searching was performed with Cochrane®, Scopus®, and Pubmed®. Inclusion and exclusion criteria were applied by MeSH term and title/abstract with clinical trial as the study design. Critical appraisal was performed for eligible article.Results: There were three articles relevant with the eligibility criteria and clinical question. One study  found that omega-3 supplementation did not give a significant effect on HbA1c. The other two studies. found that there were improvement on HbA1c and lipid profile in patients that consumed omega 3.Conclusions: Omega-3 supplementation has inconsistent results for the improvement of HbA1c. The omega-3 lowering effect of HbA1c depends on the source, dosage, and duration of supplementation.

Fatty acid profile of the erythrocyte membrane preceding development of Type 2 diabetes mellitus

2008 ◽  
Vol 18 (7) ◽  
pp. 503-510 ◽  
Author(s):  
Benno Krachler ◽  
Margareta Norberg ◽  
Jan W. Eriksson ◽  
Göran Hallmans ◽  
Ingegerd Johansson ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Fatty Acid ◽  
Erythrocyte Membrane ◽  
Fatty Acid Profile

scholarly journals Levels of soluble cell adhesion molecules in type 2 diabetes mellitus patients with macrovascular complications

2019 ◽  
Vol 48 (4) ◽  
pp. 030006051989385
Author(s):  
Gehan A Hegazy ◽  
Zuhier Awan ◽  
Enayat Hashem ◽  
Nabil Al-Ama ◽  
Asmaa Basha Abunaji
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cell Adhesion ◽  
Adhesion Molecules ◽  
Adhesion Molecule ◽  
Serum Levels ◽  
Macrovascular Complications ◽  
Soluble Adhesion Molecules

Objective Type 2 diabetes mellitus (T2DM) is a main risk factor for development of cardiovascular diseases (CVDs) and endothelial dysfunction. This study aimed to investigate serum levels of soluble vascular cell adhesion molecule 1 (sVCAM-1), intercellular adhesion molecule 1 (sICAM-1), and endothelium selectin (sE-selectin) in T2DM patients with macrovascular complications. Methods A cross-sectional study of 21 controls, 30 T2DM patients without CVDs, and 30 T2DM patients with CVDs was conducted. Serum levels of soluble adhesion molecules including sVCAM-1, sICAM-1, and sE-selectin were determined using ELISA. Results Serum levels of sVCAM-1, sICAM-1, and sE-selectin were higher in T2DM patients than in controls. Levels of serum sVCAM-1 were higher in T2DM patients with CVDs compared with T2DM patients without CVDs. In T2DM patients with CVDs, significant positive associations were observed between sVCAM-1, sICAM-1, and sE-selectin levels (r = 0.575, p = 0.001 and r = 0.378, p = 0.040). Conclusions Circulating levels of soluble adhesion molecules were elevated in T2DM patients, regardless of whether the patients had cardiovascular complications. Only sVCAM-1 was considered a useful marker for the prediction of CVDs in T2DM patients.

Sign in / Sign up

Export Citation Format

Share Document