Patients with late-onset depression have poor cognitive function at old age

2001 ◽  
Vol 49 (2) ◽  
pp. 231-233 ◽  
Author(s):  
Eric Van Exel ◽  
Rudi G.J. Westendorp ◽  
Max L. Stek ◽  
Willem Van Tilburg ◽  
Aartjan T.F. Beekman ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Old Age ◽  
Late Onset ◽  
Poor Cognitive Function

scholarly journals Late Menarche, Not Reproductive Period, Is Associated with Poor Cognitive Function in Postmenopausal Women in Taiwan

2021 ◽  
Vol 18 (5) ◽  
pp. 2345
Author(s):  
Hung-Tse Chou ◽  
Pei-Yu Wu ◽  
Jiun-Chi Huang ◽  
Szu-Chia Chen ◽  
Wan-Yi Ho
Keyword(s):  
Cognitive Function ◽  
Postmenopausal Women ◽  
Old Age ◽  
Mmse Score ◽  
Linear Regression Analysis ◽  
Reproductive Period ◽  
Age At Menarche ◽  
Female Sex Hormones ◽  
Poor Cognitive Function ◽  
One Year

Female sex hormones such as estrogen and progesterone play an important role in the regulation of a woman’s body, including cognition and neurogenesis. However, the effects of age at menarche and reproductive period on cognitive function are still controversial. The aim of this study was to investigate the relationships between age at menarche and reproductive period with cognitive impairment. Data were obtained from the Taiwan Biobank. Cognitive function was assessed using the Mini Mental State Examination (MMSE) and its five subdomains. Multivariable linear regression analysis revealed that an old age at menarche (per one year; coefficient β, −0.189; p = 0.020) was significantly associated with a low total MMSE score, whereas reproductive period (p = 0.733) was not significantly associated with total MMSE score. Furthermore, an old age at menarche was significantly associated with low MMSE G2 (registration) (per one year; coefficient β, −0.022; p = 0.035) and G5 (language, construction and obey) scores (per one year; coefficient β, −0.054; p = 0.047). However, age at menarche was not significantly associated with MMSE G1 (orientation), G3 (attention and calculation) and G4 (recall) scores. In addition, reproductive period was not significantly associated with any MMSE subscores. Late menarche was associated with poor cognitive function, including low total MMSE score and low MMSE G2 and G5 scores. However, reproductive period was not associated with cognitive function in postmenopausal women.

Parkinsonian signs and cognitive function in old age

2005 ◽  
Vol 11 (05) ◽  
Author(s):  
DEBRA A. FLEISCHMAN ◽  
ROBERT S. WILSON ◽  
JULIA L. BIENIAS ◽  
DAVID A. BENNETT
Keyword(s):  
Cognitive Function ◽  
Old Age

scholarly journals The impact of early life factors on cognitive function in old age: The Hordaland Health Study (HUSK)

2013 ◽  
Vol 1 (1) ◽  
Author(s):  
Jens Christoffer Skogen ◽  
Simon Øverland ◽  
A David Smith ◽  
Arnstein Mykletun ◽  
Robert Stewart
Keyword(s):  
Cognitive Function ◽  
Old Age ◽  
Early Life ◽  
Health Study ◽  
Early Life Factors ◽  
The Impact

Cognitive function and risk for depression in old age: a meta-analysis of published literature

2010 ◽  
Vol 23 (4) ◽  
pp. 516-525 ◽  
Author(s):  
Chang-Quan Huang ◽  
Zheng-Rong Wang ◽  
Yong-Hong Li ◽  
Yi-Zhou Xie ◽  
Qing-Xiu Liu
Keyword(s):  
Cognitive Impairment ◽  
Relative Risk ◽  
Cognitive Function ◽  
Longitudinal Studies ◽  
Old Age ◽  
Meta Analysis ◽  
Incidence Rates ◽  
Cochrane Library ◽  
Cross Sectional ◽  
Risk For Depression

ABSTRACTBackground: We assessed the relationship between cognitive impairment (including mild cognitive impairment with no signs of dementia, and dementia) and risk for depression in old age (60 years and older).Methods: MEDLINE, EMBASE and the Cochrane Library database were used to identify potential studies. All of the clinical studies that produced data on the association between cognitive function and risk of depression among individuals aged 55 years or older were identified and included in this review. The studies were classified into cross-sectional and longitudinal subsets. The quantitative meta-analysis of cross-sectional and longitudinal studies were performed. For prevalence and incidence rates of depression, odds risk (OR) and relative risk (RR) were calculated, respectively.Results: Since all but two studies found in the search were for individuals aged 60 years or over, we assessed and reported on results for this larger group only. In this review we included 13 cross-sectional and four prospective longitudinal studies. The quantitative meta-analysis showed that, in old age, individuals with non-dementia cognitive impairment had neither significant higher prevalence nor incidence rates of depression than those without (odds risk (OR): 1.48, 95% confidence intervals (95% CI): 0.87–2.52; relative risk (RR): 1.12, 95% CI: 0.62–2.01). In old age, individuals with dementia had both significant higher prevalence and incidence rates of depression than those without (OR: 1.82, 95% CI: 1.15–2.89; RR: 3.92, 95% CI: 1.93–7.99).Conclusions: Despite the methodological limitations of this meta-analysis, we found that in old age, there was no association between depression and cognitive impairment with no dementia; however, there was a definite association between depression and dementia and thus dementia might be a risk for depression.

scholarly journals Gender Differences in the Association Between Leisure Activity in Adulthood and Cognitive Function in Old Age: A Prospective Longitudinal Population-Based Study

2017 ◽  
Vol 75 (1) ◽  
pp. 11-20 ◽  
Author(s):  
Linda B Hassing
Keyword(s):  
Gender Differences ◽  
Cognitive Function ◽  
Old Age ◽  
Spatial Ability ◽  
Cognitive Aging ◽  
Leisure Activities ◽  
Verbal Ability ◽  
Leisure Activity ◽  
Cultural Activity ◽  
Prospective Longitudinal

Abstract Objectives To examine the long-term association between leisure activities in adulthood and cognitive function in old age while recognizing gender differences in activity profiles. Methods The sample included 340 cognitively healthy twins enrolled in the OCTO-Twin Study, a longitudinal study on cognitive aging. Leisure activity was measured in midlife and cognitive function in old age (mean age 83). Leisure activities covered the domains of domestic, intellectual–cultural, and self-improvement activities. The cognitive assessments comprised 5 measurement occasions (2-year intervals) covering verbal ability, spatial ability, memory, and speed. The association between leisure activity and cognitive function was estimated separately for the genders using growth curve models, adjusting for age and education. Results Men and women had the same level of total leisure activity but differed in activity profiles and in the associations between activity and cognitive function. Higher engagement in self-improvement among men was related to higher level of cognitive functioning. Among women, intellectual–cultural activity was related to better verbal ability and memory. Concerning trajectories of cognitive function, domestic activity among men was related to less decline in speed, whereas for women it was related to steeper decline in spatial ability and memory. Further, higher intellectual–cultural activity among women was related to steeper decline in memory. Discussion Cognitively stimulating activities (i.e., self-improvement and intellectual–cultural), might increase cognitive reserve whereas less cognitively stimulating activities (i.e., domestic) do not. Gender differences should be considered when examining lifestyle factors in relation to cognitive aging.

Sign in / Sign up

Export Citation Format

Share Document