scholarly journals Therapeutic uses and efficacy of botulinum toxin in orofacial medicine

2018 ◽  
Vol 24 (1) ◽  
pp. 11-21
Author(s):  
Kinz Bayet ◽  
Luc Chikhani ◽  
Anne-Laure Ejeil
Keyword(s):  
Botulinum Toxin ◽  
Cosmetic Surgery ◽  
Myofascial Pain ◽  
Scientific Evidence ◽  
Good Practice ◽  
Mouth Opening ◽  
Randomized Controlled ◽  
Therapeutic Uses ◽  
Levator Labii Superioris ◽  
High Level

Introduction: Botulinum toxin, primarily known for its use in cosmetic surgery, is also used for therapeutic purposes in many medical fields. It works as a muscle relaxant and inhibits glandular secretions. In the orofacial sphere, the use of this toxin is proposed in particular for disabling myofascial pain and aberrant salivary disorders. Methodology: A critical analysis of the literature, based on PUBMED data, concerning the orofacial indications of botulinum toxin was carried out. Results: The literature is abundant regarding the therapeutic interest of this toxin for several oral pathologies, but scientific merits vary markedly from one indication to another. Discussion: The musculorelaxant and antisecretory action of this toxin appears to be demonstrated in the case of bruxism, limitation of the mouth opening and in hypersialorrhea. On the other hand, its medical benefit is still not supported by scientific evidence for masseter hypertrophy, tonicity of the levator labii superioris muscles, sialocele fistulae and Frey's syndrome. Conclusion: Additional high-level studies, unbiased, randomized controlled trials, are required to eliminate the uncertainties that persist about the clinical impact of botulinum toxin and to justify the development of recommendations for good practice valid and credible.

scholarly journals Modified-Active Release Therapy in Patients with Scapulocostal Syndrome and Masticatory Myofascial Pain: A Stratified-Randomized Controlled Trial

2021 ◽  
Vol 18 (16) ◽  
pp. 8533
Author(s):  
Wilawan Kanhachon ◽  
Yodchai Boonprakob
Keyword(s):  
Randomized Controlled Trial ◽  
Myofascial Pain ◽  
Pain Catastrophizing ◽  
Controlled Trial ◽  
Pressure Pain Threshold ◽  
Mouth Opening ◽  
Control Group ◽  
Randomized Controlled ◽  
Active Release ◽  
Hot Pack

Modified-active release therapy (mART) was developed to treat patients experiencing upper quarter pain. The objective of the study was to determine the effectiveness of the mART in treating pain, promoting function, and measuring emotions in patients with scapulocostal syndrome (SCS) and masticatory myofascial pain (MMP). A stratified-randomized controlled trial was employed in 38 participants separated into two groups. All participants underwent the same series visual analog scale (VAS), pressure pain threshold (PPT), mouth opening (MO), maximum mouth opening (MMO), craniovertebral angle (CV-angle), and pain catastrophizing scale Thai version (PCS-Thai-version) at the baseline. The mART group underwent the mART program three times a week for 4 weeks with a hot pack and an educational briefing while the control group received only a hot pack and the educational briefing. After treatment, both groups showed significant improvement (p < 0.05) in all parameters except MO, MMO, and CV-angle. When comparing outcomes between the groups, the mART group showed a statistically significant greater number of improvements than did the control group. In conclusion, the mART program can improve pain experienced by patients with SCS and MMP and it can be used as an adjuvant technique with conservative treatment.

scholarly journals Assessing the effectiveness of botulinum toxin injections into masticatory muscles in the treatment of temporomandibular disorders

2018 ◽  
Vol 24 (3) ◽  
pp. 107-111 ◽  
Author(s):  
Alexis Kahn ◽  
Helios Bertin ◽  
Pierre Corre ◽  
Morgan Praud ◽  
Arnaud Paré ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Temporomandibular Disorders ◽  
Myofascial Pain ◽  
Mouth Opening ◽  
Masticatory Muscles ◽  
University Hospital ◽  
Duration Of Action ◽  
Beneficial Effects ◽  
Duration Of Effect ◽  
The Mean

Introduction: Temporomandibular disorders (TMD) are a common and invalidating disease sometimes difficult to treat. Current international recommendations favour reversible and non-invasive treatments, including the injection of botulinum toxin (BTX) into masticatory muscles. There is no strong evidence of its effectiveness. Objective: The main goal of this study was to assess the effectiveness of BTX six months following injection, in terms of pain, mouth opening, improvement of symptoms and duration of effect. Materials and methods: A retrospective study carried out at Nantes University Hospital between 2014 and 2016. Results: Thirty-four patients were included. The mean age was 37 years (17–76) and seventy six percents were female. Eighty percent of patients reported a significant improvement, notably in cases of arthralgia, which decreased in 8/18 (44%) patients (p < 0.05). The mean duration of measured efficacy was 4.2 months. Discussion: Significant improvement in cases of arthralgia and a tendency for improvement in cases of myalgia, with a mean duration of action of 4.2 months. Although BTX injection do not guarantee complete resolution of myofascial pain, it have been shown to have beneficial effects on some symptoms have been shown. Conclusion: Botulinum toxin should be considered as an alternative treatment when other conservative methods fail to yield satisfactory results. A thorough multicentre assessment is necessary in the future to scientifically validate its use.

scholarly journals Acupuncture in Temporomandibular Disorders Painful Symptomatology: An Evidence-Based Case Report

2020 ◽  
Vol 14 (04) ◽  
pp. 692-696
Author(s):  
Lia Dietrich ◽  
Igor Vinícius Santos Rodrigues ◽  
Marcelo Dias Moreira de Assis Costa ◽  
Roberta Furtado Carvalho ◽  
Gisele Rodrigues da Silva
Keyword(s):  
Case Report ◽  
Chinese Medicine ◽  
Temporomandibular Disorders ◽  
Myofascial Pain ◽  
Scientific Evidence ◽  
Muscle Relaxation ◽  
Mouth Opening ◽  
Evidence Based ◽  
Complementary Treatment ◽  
Emotional Balance

AbstractTemporomandibular dysfunction (TMD) is complex and multifactorial. Its etiology involves various factors, such as malocclusion, psychological patterns, parafunctional habits, and the temporomandibular joint anatomy. Symptoms include myofascial pain, joint clicking, mouth opening limitation, headaches, earaches, and neck pain, comprising one of the greatest causes of nondental pain. Acupuncture has been used to treat these conditions by acting locally both in muscle relaxation and pain management as well as reaching physical, mental, and emotional balance. The aim of this study is to present a brief literature review reporting the efficacy of acupuncture on TMDs and a case report in which the painful symptomatology of TMD was treated with a systemic protocol, based on scientific evidence and concepts of traditional Chinese medicine. Acupuncture may be a complementary treatment for TMD, and in this case report, it eliminated the patient’s painful symptomatology.

scholarly journals The effect of laser and botulinum toxin in the treatment of myofascial pain and mouth opening: A randomized clinical trial

2016 ◽  
Vol 159 ◽  
pp. 120-123 ◽  
Author(s):  
Bethânia Molin Giaretta De Carli ◽  
Alessandra Kuhn Dall Magro ◽  
Bianca Núbia Souza-Silva ◽  
Felipe de Souza Matos ◽  
João Paulo De Carli ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Botulinum Toxin ◽  
Randomized Clinical Trial ◽  
Myofascial Pain ◽  
Mouth Opening

scholarly journals Botulinum toxin for treating muscular temporomandibular disorders: a systematic review

2012 ◽  
Vol 17 (6) ◽  
pp. 167-171 ◽  
Author(s):  
Eduardo Machado ◽  
Lívia Zuchetto dos Santos ◽  
Lilian Gonçalves Custódio ◽  
Paulo Afonso Cunali
Keyword(s):  
Clinical Trials ◽  
Botulinum Toxin ◽  
Temporomandibular Disorders ◽  
Myofascial Pain ◽  
Controlled Clinical Trial ◽  
Controlled Clinical Trials ◽  
Double Blind ◽  
The Real ◽  
Randomized Controlled Clinical Trials ◽  
Randomized Controlled

OBJECTIVE: This study, through a systematic literature review, aims to analyze the effectiveness of Botulinum Toxin as a treatment for masticatory myofascial pain and muscles temporomandibular disorders (TMD). METHODS: Survey in research bases: MEDLINE, Cochrane, EMBASE, Pubmed, Lilacs and BBO, between the years of 1966 and April 2011, with focus in randomized or quasi-randomized controlled clinical trials, blind or double-blind. RESULTS: After applying the inclusion criteria, 4 articles comprised the final sample: 3 were double-blind randomized controlled clinical trials and 1 was single-blind randomized controlled clinical trial. CONCLUSIONS: According to the literature, there is lack of evidence about the real effectiveness of botulinum toxin in the treatment of masticatory myofascial pain and muscular TMD. Thus, further randomized controlled clinical trials, with representative samples and longer follow-up time, to assess the real effectiveness of the technique are needed.

(Preprint)

2018 ◽  
Author(s):  
Dr Malathi Dayalan ◽  
Dr Sudeshna Sharma ◽  
Dr Shweta Poovani ◽  
Dr Saher Altaf
Keyword(s):  
Myofascial Pain ◽  
Mouth Opening ◽  
Masticatory Muscles ◽  
Matched Pair ◽  
Masticatory Muscle ◽  
Muscle Disorders ◽  
Occlusal Contact ◽  
Group I ◽  
Group Ii

BACKGROUND Masticatory system is a complex functional unit, primarily engaged in chewing, swallowing and breathing functions, and some parts are involved in taste recognition and determination of food consistency. Sophisticated functional performances of speech and emotional expressions are specifically human qualities. Irregularities in occlusion appears to be the precipitating factor in the pathogenesis of myofascial pain dysfunction syndrome. Tek- Scan III records the bite length, number, distribution, timing, duration and the relative force of each tooth contact. It also records the sequence of occlusal contacts in terms of time and the associated force with each occlusal contact. The aim of this study was to treat masticatory muscle disorders with occlusal equilibration, and compare the efficacy of treatment outcomes between selective grinding and stabilization splints using Tek-Scan III. OBJECTIVE Objective of this study was to compare the efficacy of occlusal equilibration achieved through selective griding and stabilization splints using Tek-Scan III. METHODS In this in vivo study, 40 patients with masticatory muscle disorders were selected based on the inclusion and exclusion criteria. The occlusal discrepancies were analyzed using Tek-Scan III. The selected 40 subjects were then randomly divided into 2 groups based on the treatment they recieved; Group I – Selective grinding group (20) and Group II – Stabilization splint group (20). Comparison of pre-treatment and post treatment results were evaluated in terms of pain, mouth opening, left and right side force percentage as recorded through Tek-Scan III and reduction of disclusion time. Statistical analysis was carried out with Kolmogorov Smirnov test, Wilcoxon matched pair test and Mann-Whitney U test. RESULTS Wilcoxon matched pairs test demonstrated that there was statistically significant results ( p = 0.0007) in both the groups for reduction of disclusion time, elimination of pain and improved mouth opening. Patients in Group I showed better results as compared to Group II in terms of disclusion time, pain and mouth opening. CONCLUSIONS Occlusal equilibration brought about by reducing the disclusion time using the Tek- Scan III reduced the symptoms of pain in masticatory muscles. Patients in group I (Selective grinding) however showed better results when compared to patients in group II (Stabilization splints).

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