A Randomized Trial of Pulsatile Perfusion Using an Intra-Aortic Balloon Pump Versus Nonpulsatile Perfusion on Short-Term Changes in Kidney Function During Cardiopulmonary Bypass During Myocardial Reperfusion

2007 ◽  
Vol 50 (2) ◽  
pp. 229-238 ◽  
Author(s):  
Francesco Onorati ◽  
Pierangela Presta ◽  
Giorgio Fuiano ◽  
Pasquale Mastroroberto ◽  
Nicolino Comi ◽  
...  
2009 ◽  
Vol 35 (6) ◽  
pp. 1012-1019 ◽  
Author(s):  
Francesco Onorati ◽  
Giuseppe Santarpino ◽  
Gelsomina Tangredi ◽  
Giorgio Palmieri ◽  
Antonino S. Rubino ◽  
...  

Author(s):  
M. O. Magnusson ◽  
D. G. Osborne ◽  
T. Shimoji ◽  
W. S. Kiser ◽  
W. A. Hawk

Short term experimental and clinical preservation of kidneys is presently best accomplished by hypothermic continuous pulsatile perfusion with cryoprecipitated and millipore filtered plasma. This study was undertaken to observe ultrastructural changes occurring during 24-hour preservation using the above mentioned method.A kidney was removed through a midline incision from healthy mongrel dogs under pentobarbital anesthesia. The kidneys were flushed immediately after removal with chilled electrolyte solution and placed on a LI-400 preservation system and perfused at 8-10°C. Serial kidney biopsies were obtained at 0-½-1-2-4-8-16 and 24 hours of preservation. All biopsies were prepared for electron microscopy. At the end of the preservation period the kidneys were autografted.


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