The ONE Study: One Small Step for Patient Care, a Giant Leap for Cell Therapy

The Gram stain is one of the most commonly performed tests in the clinical microbiology laboratory, yet it is poorly controlled and lacks standardization. It was once the best rapid test in microbiology, but it is no longer trusted by many clinicians. The publication by Samuel et al. (J. Clin. Microbiol. 54:1442–1447, 2016,http://dx.doi.org/10.1128/JCM.03066-15) is a start for those who want to evaluate and improve Gram stain performance. In an age of emerging rapid molecular results, is the Gram stain still relevant? How should clinical microbiologists respond to the call to reduce Gram stain error rates?

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One small step for exosomes, one giant leap for Kawasaki disease

Revista Portuguesa de Cardiologia ◽

10.1016/j.repc.2016.03.002 ◽

2016 ◽

Vol 35 (5) ◽

pp. 275-276

Author(s):

Henrique Girão

Keyword(s):

Kawasaki Disease ◽

Small Step ◽

Giant Leap

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One small step for e-voting, one giant leap for democracy

Journal of Geography Politics and Society ◽

10.26881/jpgs.2020.1.01 ◽

2020 ◽

Vol 10 (1) ◽

Author(s):

Marina Gorbatiuc

Keyword(s):

Human Rights ◽

Law Enforcement ◽

International Organizations ◽

The Internet ◽

Mutual Understanding ◽

Small Step ◽

Law Enforcement Training ◽

Republic Of Moldova ◽

Giant Leap ◽

The Republic

E-voting is the next step of the Republic of Moldova evolution. The article presents advantages of e-voting, all steps of using it, and its many types. Electronic voting refers to elections using electronic means. E-voting can be managed by phones, the Internet, private computer networks or special kiosks. Reasons for accepting this kind of voting are provided. The analyzed in the article OSCE/ODIHR’s (Office for Democratic Institutions and Human Rights) activities which are related to tolerance and non-discrimination are focus on the following areas: legislation; law enforcement training; monitoring, reporting on, and following up on responses to hate-motivated crimes and incidents; as well as educational activities to promote tolerance, respect, and mutual understanding. Conclusions from all ODIHR activities which are carried out in close co-ordination and co-operation with OSCE participating States, OSCE institutions and field operations, as well as with other international organizations are given.

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Quadruple-decker phthalocyanines — one additional layer for a molecule, one giant leap for phthalocyanine chemistry

Journal of Porphyrins and Phthalocyanines ◽

10.1142/s1088424614500461 ◽

2014 ◽

Vol 18 (08n09) ◽

pp. 615-629 ◽

Cited By ~ 4

Author(s):

Takamitsu Fukuda ◽

Naoto Ishikawa

Keyword(s):

Alternate Current ◽

Infrared Region ◽

Electronic Transitions ◽

Magnetic Susceptibility Data ◽

Susceptibility Data ◽

Additional Layer ◽

Synthetic Strategy ◽

Energy Gaps ◽

Giant Leap ◽

The One

The synthesis, and spectroscopic and magnetic properties of quadruple-decker phthalocyanines (Pcs) have been reviewed. While the presence of stacked mercury Pc oligomers was proposed as early as 1992, the isolation of a quadruple-decker Pc was first achieved in 2010. Herein, we review how the synthetic strategy for quadruple-decker Pcs has come to be conceived from the recent development of cadmium Pc oligomers, which will be followed by illustration of unique physicochemical properties originating from the structure of the quadruple-decker frameworks. In the spectroscopy section, the electronic structures of the quadruple-decker Pc are discussed based on the theoretical and experimental results. A simple molecular orbital (MO) method predicts that energy gaps among the occupied frontier MOs of the quadruple-decker Pc become smaller than those of double- or triple-decker Pcs, leading to the observation of exceptionally low-lying electronic transitions for the oxidized quadruple-decker Pcs. It has been confirmed that the corresponding lowest π–π* electronic transitions reach the infrared region for the one-electron oxidized quadruple-decker Pcs. In the magnetic property section, a clear evidence of the long-range magnetic dipole–dipole f–f interactions between two f-electronic centers of diterbium quadruple-decker Pc is provided, and its magnetic relaxation phenomena arising mainly from quantum tunneling magnetizations (QTMs) will be discussed by using the alternate current (ac) magnetic susceptibility data, and the numerically calculated Zeeman diagram of the f-electronic centers in the quadruple-decker Pc.

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