scholarly journals Vitamin D Regulation of the Uridine Phosphorylase 1 Gene and Uridine-Induced DNA Damage in Colon in African Americans and European Americans

2018 ◽  
Vol 155 (4) ◽  
pp. 1192-1204.e9 ◽  
Author(s):  
Nobel Bhasin ◽  
Dereck Alleyne ◽  
Olivia A. Gray ◽  
Sonia S. Kupfer
Keyword(s):  
Vitamin D ◽  
Dna Damage ◽  
African Americans ◽  
Uridine Phosphorylase ◽  
European Americans

scholarly journals Common vitamin D pathway gene variants reveal contrasting effects on serum vitamin D levels in African Americans and European Americans

2014 ◽  
Vol 133 (11) ◽  
pp. 1395-1405 ◽  
Author(s):  
Ken Batai ◽  
Adam B. Murphy ◽  
Ebony Shah ◽  
Maria Ruden ◽  
Jennifer Newsome ◽  
...  
Keyword(s):  
Vitamin D ◽  
African Americans ◽  
Serum Vitamin ◽  
Gene Variants ◽  
Serum Vitamin D ◽  
European Americans ◽  
Pathway Gene ◽  
Vitamin D Levels

Differences between European Americans and African Americans in the Association between Child Obesity and Disrupted Parenting

2008 ◽  
Vol 39 (4) ◽  
pp. 589-610 ◽  
Author(s):  
Leslie Gordon Simons ◽  
Ellen Granberg ◽  
Yi-Fu Chen ◽  
Ronald L. Simons ◽  
Rand D. Conger ◽  
...  
Keyword(s):  
African Americans ◽  
Child Obesity ◽  
European Americans

Differences between European Americans and African Americans in the Association between Child Obesity and Disrupted Parenting

2008 ◽  
Vol 39 (2) ◽  
pp. 207-228
Author(s):  
Leslie Gordon Simons ◽  
Gene R. Brody ◽  
Velma M. Murry ◽  
Ellen Granberg ◽  
Yi-Fu Chen ◽  
...  
Keyword(s):  
African Americans ◽  
Child Obesity ◽  
European Americans

scholarly journals Obesity, oxidative DNA damage and vitamin D as predictors of genomic instability in children and adolescents

2021 ◽  
Author(s):  
Moonisah Usman ◽  
Maria Woloshynowych ◽  
Jessica Carrilho Britto ◽  
Ivona Bilkevic ◽  
Bethany Glassar ◽  
...  
Keyword(s):  
Vitamin D ◽  
Dna Damage ◽  
Genomic Instability ◽  
Oxidative Dna Damage ◽  
Nutritional Deficiencies ◽  
Aetiological Factor ◽  
Enzyme Linked Immunosorbent Assay ◽  
Childhood And Adolescence ◽  
Paediatric Obesity ◽  
Vitamin D Levels

Abstract Background/objectives Epidemiological evidence indicates obesity in childhood and adolescence to be an independent risk factor for cancer and premature mortality in adulthood. Pathological implications from excess adiposity may begin early in life. Obesity is concurrent with a state of chronic inflammation, a well-known aetiological factor for DNA damage. In addition, obesity has been associated with micro-nutritional deficiencies. Vitamin D has attracted attention for its anti-inflammatory properties and role in genomic integrity and stability. The aim of this study was to determine a novel approach for predicting genomic instability via the combined assessment of adiposity, DNA damage, systemic inflammation, and vitamin D status. Subjects/methods We carried out a cross-sectional study with 132 participants, aged 10–18, recruited from schools and paediatric obesity clinics in London. Anthropometric assessments included BMI Z-score, waist and hip circumference, and body fat percentage via bioelectrical impedance. Inflammation and vitamin D levels in saliva were assessed by enzyme-linked immunosorbent assay. Oxidative DNA damage was determined via quantification of 8-hydroxy-2′-deoxyguanosine in urine. Exfoliated cells from the oral cavity were scored for genomic instability via the buccal cytome assay. Results As expected, comparisons between participants with obesity and normal range BMI showed significant differences in anthropometric measures (p < 0.001). Significant differences were also observed in some measures of genomic instability (p < 0.001). When examining relationships between variables for all participants, markers of adiposity positively correlated with acquired oxidative DNA damage (p < 0.01) and genomic instability (p < 0.001), and negatively correlated with vitamin D (p < 0.01). Multiple regression analyses identified obesity (p < 0.001), vitamin D (p < 0.001), and oxidative DNA damage (p < 0.05) as the three significant predictors of genomic instability. Conclusions Obesity, oxidative DNA damage, and vitamin D deficiency are significant predictors of genomic instability. Non-invasive biomonitoring and predictive modelling of genomic instability in young patients with obesity may contribute to the prioritisation and severity of clinical intervention measures.

Supplemental Vitamin D and Calcium in the Management of African Americans With Heart Failure Having Hypovitaminosis D

2011 ◽  
Vol 341 (2) ◽  
pp. 113-118 ◽  
Author(s):  
Ayhan A. Zia ◽  
Marriyam Moten ◽  
Jesse E. McGee ◽  
Syamal K. Bhattacharya ◽  
Karl T. Weber ◽  
...  
Keyword(s):  
Heart Failure ◽  
Vitamin D ◽  
African Americans ◽  
Hypovitaminosis D ◽  
Supplemental Vitamin

Religion and Race in American Music

2018 ◽  
Author(s):  
David W. Stowe
Keyword(s):  
Native American ◽  
African Americans ◽  
Gospel Music ◽  
American Music ◽  
Social Boundaries ◽  
Worship Music ◽  
Religious Music ◽  
European Americans ◽  
Musical Adaptations ◽  
Group Identities

Religious music functions both to create group identities and to dissolve social boundaries. Historically, American music has been characterized by racial and religious crossover. While many ethnic groups have participated in constituting American music, the most seminal crossovers have occurred between African and European Americans. Jazz was shaped largely by the interactions of Jews and African Americans. Gospel music developed from the interaction of vernacular slave spirituals, Protestant hymns, and the secular blues. Christian hymns have been thoroughly indigenized by many Native American groups. Compared to Buddhists and Jews, American Hindus and Muslims have made few musical adaptations of their worship music, but their music has been widely sampled in American popular styles. In recent decades, mainline Protestant hymnals have come to reflect the deeply multicultural reality of American sacred song.

Vitamin D Deficiency is Associated With the Development of Subclinical Coronary Artery Disease in African Americans With HIV Infection

2012 ◽  
Vol 60 (5) ◽  
pp. 801-807 ◽  
Author(s):  
Hong Lai ◽  
Barbara Detrick ◽  
Elliot K. Fishman ◽  
Gary Gerstenblith ◽  
Jeffrey A. Brinker ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Vitamin D ◽  
Coronary Artery ◽  
African Americans ◽  
Hiv Infection ◽  
Vitamin D Deficiency ◽  
Artery Disease
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