Long-term mortality and morbidity of transfusion-associated non-A, non-B, and type C hepatitis: A National Heart, Lung, and Blood Institute collaborative study

Hepatology ◽  
2001 ◽  
Vol 33 (2) ◽  
pp. 455-463 ◽  
Author(s):  
L Seeff
Keyword(s):  
Hepatitis A ◽  
Collaborative Study ◽  
Mortality And Morbidity ◽  
Blood Institute ◽  
National Heart ◽  
National Heart Lung ◽  
Type C ◽  
Long Term Mortality

Long-term follow-up of coronary angioplasty: the 1977-1981 national heart, lung, and blood institute registry

1989 ◽  
Vol 10 (suppl G) ◽  
pp. 36-41 ◽  
Author(s):  
M.G. Bourassa ◽  
J. W. Wilson ◽  
K. M. Detre ◽  
S. F. Kelsey ◽  
T. Robertson ◽  
...  
Keyword(s):  
Coronary Angioplasty ◽  
Blood Institute ◽  
National Heart ◽  
National Heart Lung ◽  
Long Term Follow Up

scholarly journals Midlife moderation-quantified healthy diet and 40-year mortality risk from CHD: the prospective National Heart, Lung, and Blood Institute Twin Study

2016 ◽  
Vol 116 (2) ◽  
pp. 326-334 ◽  
Author(s):  
Jun Dai ◽  
Ruth E. Krasnow ◽  
Terry Reed
Keyword(s):  
Mortality Risk ◽  
Twin Study ◽  
Healthy Diet ◽  
Familial Predisposition ◽  
Dietary History ◽  
Blood Institute ◽  
National Heart ◽  
National Heart Lung ◽  
Chd Risk Factors

AbstractIt is unknown whether influences of midlife whole diet on the long-term CHD mortality risk are independent of genetic and common environmental factors or familial predisposition. We addressed this question prospectively using data from the National Heart, Lung, and Blood Institute Twin Study. We included 910 male twins who were middle-aged and had usual diet assessed with nutritionist-administered, cross-checked dietary history interview at baseline (1969–1973). Moderation-quantified healthy diet (MQHD), a dietary pattern, was created to evaluate a whole diet. Primary outcome was time-to-CHD death. Hazard ratios (HR) were estimated using frailty survival model. Known CHD risk factors were controlled. During the follow-up of 40 years through 31 December 2009, 113 CHD deaths, 198 total cardiovascular deaths and 610 all-cause deaths occurred. In the entire cohort, the multivariable-adjusted HR for the overall association (equivalent to a general population association) was 0·76 (95 % CI 0·66, 0·88) per 10-unit increment in the MQHD score for CHD, and the multivariable-adjusted HR for a twin with a MQHD score ten units higher than his co-twin brother was 0·79 (95 % CI 0·64, 0·96, P=0·02) for CHD independent of familial predisposition. Similar results were found for a slightly more food-specified alternative moderation-quantified healthy diet (aMQHD). The between-pair association (reflecting familial influence) was significant for CHD for both MQHD and aMQHD. It is concluded that associations of MQHD and aMQHD with a lower long-term CHD mortality risk are both nutritionally and familially affected, supporting their use for dietary planning to prevent CHD mortality.

scholarly journals How the National Heart, Lung, and Blood Institute (NHLBI) Develops Research Priorities and Supports Critical Care Research

2012 ◽  
Vol 92 (12) ◽  
pp. 1489-1493 ◽  
Author(s):  
Andrea L. Harabin ◽  
James P. Kiley
Keyword(s):  
Critical Care ◽  
Research Priorities ◽  
National Institutes Of Health ◽  
Patient Centered ◽  
Ongoing Research ◽  
Blood Institute ◽  
National Heart ◽  
National Heart Lung ◽  
Research Questions

This report provides a brief overview of some relevant ongoing research on critical care and how research priorities are determined by the National Heart, Lung, and Blood Institute. Long-term and patient-centered outcomes have become more prominent research questions for clinical studies in patients who are critically ill. Rehabilitation research would be appropriate in this context, and funding is most likely received through investigator-initiated R01 applications. National Institutes of Health program staff are available for discussion and advice and encourage contact from extramural investigators.

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