Comparison of perinatal outcomes between patients with suspected complex and simple gastroschisis

Author(s):  
Virginia Medina Jiménez ◽  
Sandra Acevedo-Gallegos ◽  
Monica Aguinaga Rios ◽  
Juan Manuel Gallardo-Gaona

Objective: The aim of this study was to compare perinatal outcomes between patients with and without prenatal ultrasound markers predictive of complex gastroschisis. Method: A prospective cohort of 98 patients with isolated fetal gastroschisis underwent antenatal ultrasound and delivered in a tertiary referral center. Patients were classified according to eight ultrasonographic markers predictive of complexity, and perinatal outcomes were assessed accordingly. The primary outcome was the presence of fetal growth restriction and staged SILO reduction postnatally. Results: Of all fetuses, 54.1% (n = 53) displayed ultrasonographic markers predictive of complexity at 32.7 ± 4.3 weeks of gestation. Gastric dilatation was the most frequent marker followed by extra-abdominal bowel dilatation. The presence of ultrasound markers predictive of complexity, was not associated with intrauterine growth restriction but its absence was less associated with staged SILO reduction of the abdominal wall postnatally with a RR of 0.79 (CI95% 0.17-0.53) Conclusion: Fetuses with ultrasound markers that predict complexity were not associated with fetal growth restriction but its absence was less associated with staged SILO reduction of the abdominal wall postnatally. It is necessary to unify criteria, establish cut-off points and the optimal moment to measure these markers.

1970 ◽  
Vol 1 (2) ◽  
pp. 77-82
Author(s):  
Swaraj Rajbhandari ◽  
Sanu Maiya Dali

Objective: To find out the role of micronutrients in intrauterine growth restrictions. Methodology. Desktop review of articles from the year 1986 till 2005 March using key words, Micronutrients AND Intrauterine Growth Restriction. Results: 13.7 million infants are born annually with fetal growth restriction (IUGR) comprising 11% of all births in developing countries affecting up to 40% in some of developing countries varying from 14-38.8% for Nepal. Public health officials have recognized the urgent need for interventions aimed to prevent IUGR as this higher percent is likely due to protein calorie malnutrition, kwown to be the second leading cause of perinatal morbidity and mortality. The identification of IUGR is crucial because proper evaluation and management can result in a favourable outcome. Sixty five percent of IUGR are not identified until after delivery. More over, it is unrealistic issue to assume that extra nutrient taken for few months during pregnancy would replace the under nutrition that has been prevalent for over decades in terms of reproductive performance. Conclusion: Although it is frustrating that, most of the interventions aimed to prevent or treat impaired fetal growth have hardly shown any beneficial effect on short-term perinatal outcomes, long term benefit may be rewarding with significant impact. Hence provision of energy supplementation for two (or more, if they occur) consecutive pregnancies must be focused rather than during single pregnancy. Key words: micronutrients, intrauterine growth restriction, malnutrion. doi:10.3126/njog.v1i2.2407 N. J. Obstet. Gynaecol Vol. 1, No. 2, p. 77-82 Nov-Dec 2006


2012 ◽  
Vol 61 (6) ◽  
pp. 68-75 ◽  
Author(s):  
Natalya Vladimirovna Artymuk ◽  
Aleksey Gennadyevich Trishkin ◽  
Ekaterina Sergeevna Bikmetova

The article presents a review of sources concerning perinatal outcomes and long-term effects on children and adults born with intrauterine growth restriction (IUGR). Neonates with IUGR are at high risk for morbidity and mortality. The conditions of antenatal fetal life may program the range of unfavorable long-term effects in adulthood. This requires further study of the etiology, pathogenesis, diagnosis, and management of IUGR.


2017 ◽  
Vol 77 (11) ◽  
pp. 1157-1173 ◽  
Author(s):  
Sven Kehl ◽  
Jörg Dötsch ◽  
Kurt Hecher ◽  
Dietmar Schlembach ◽  
Dagmar Schmitz ◽  
...  

Abstract Aims The aim of this official guideline published and coordinated by the German Society of Gynecology and Obstetrics (DGGG) was to provide consensus-based recommendations obtained by evaluating the relevant literature for the diagnostic treatment and management of women with fetal growth restriction. Methods This S2k guideline represents the structured consensus of a representative panel of experts with a range of different professional backgrounds commissioned by the Guideline Committee of the DGGG. Recommendations Recommendations for diagnostic treatment, management, counselling, prophylaxis and screening are presented.


Author(s):  
Ashish Seal ◽  
Arup Dasgupta ◽  
Mousumi Sengupta ◽  
Rinini Dastider ◽  
Sukanta Sen

Background: Intrauterine growth restriction (IUGR) is defined as fetal growth less than the normal growth potential of a specific infant because of genetic or environmental factors. Fetal growth restriction or intrauterine growth restriction is one of the leading causes of perinatal mortality and morbidity in newborns. Fetal growth restriction is a complex multifactorial condition resulting from several fetal and maternal disorders. Objective of present study was to find out incidence of IUGR and assessment and evaluation of different important changes in IUGR.Methods: Women who attended the Obstetric OPD in their 1st trimester of pregnancy and those who were thought would be able to visit the antenatal clinic for their fortnightly check-up regularly were screened for intrauterine foetal growth retardation. Women with irregular and uncertain menstrual history and where the 1st trimester USG foetal crown rump length did not corroborate with the menstrual gestational age were excluded from this study.Results: Incidence of IUGR was 18.2% and 84% were found to be asymmetrical. IUGR was found to be double among primigravids and women above 30 years. It had been observed that IUGR was associated with certain conditions like short stature (52%), pregnancy induced hypertension (24%) and anaemia (12%).Conclusions: Thus, early USG screening along with robust screening for maternal BMI, nutritional status, and anaemia can assist the obstetric team in providing early diagnosis, prompt intervention, and better outcome in pregnancy with fetal growth restriction.


2019 ◽  
Vol 37 (06) ◽  
pp. 647-651
Author(s):  
Beth L. Pineles ◽  
Sarah Crimmins ◽  
Ozhan Turan

Abstract Objective This study aimed to identify the optimal gestational age for delivery of pregnancies complicated by fetal growth restriction (FGR) without Doppler abnormalities. Study Design Cases of FGR (ultrasound-estimated fetal weight less than the 10th or abdominal circumference less than the 5th percentile for gestational age) without fetal Doppler abnormalities were identified from a fetal ultrasound database. The primary outcome was a composite of perinatal mortality and morbidity. The risk of the primary outcome for each gestational age was compared with pregnancies delivered at 390/7 to 406/7 weeks. Odds ratios were adjusted for potential confounders. Results The analysis included 1,024 pregnancies. FGR was identified at a median of 235/7 weeks (range: 20–42 weeks). Four cases of fetal death (234/7—376/7 weeks) and no neonatal deaths were included. The primary outcome occurred in 209 patients (20.4%). This was greater for patients delivered at less than 37 weeks' gestation than for those delivered at or after 39 weeks' gestation, with no increased risk after 40 weeks. Conclusion Among pregnancies complicated by suspected FGR without Doppler abnormalities, delivery at 39 weeks is safe with no difference in perinatal outcomes from 37 to 42 weeks.


2018 ◽  
Vol 22 (1) ◽  
pp. 160-162
Author(s):  
A.M. Berbets

Objective – to study the reasons of appearance, terms of manifestation and types of the sleep disorders in pregnant women with intrauterine growth restriction of fetus. 80 pregnant women with placental insufficiency, manifesting as intrauterine fetal growth restriction (IUGR) of II–III degree in the 3rd pregnancy trimester (study group) and 30 women with normal clinical flow of pregnancy (control group) were questioned. They were asked about pregnancy term when the complains of the sleep disorders were firstly expressed, as well as about types of the sleep disorders and their frequency (in times per week). Questioning showed that pregnant women with IUGR in 86% cases experience the sleep disorders starting from pregnancy term 12–22 weeks (healthy pregnant women — mostly after 30 weeks, 57% cases), more commonly wake up 2 or more times per night (71% of positive answers, in control group – 23%), and 3 or more times per week (78% of positive answers, in control group – 17%). Thus, sleep disorders in pregnant women with IUGR appear earlier and seem to be more expressed then in pregnant women with normal fetal growth. Expression of the complains of insomnia, in our opinion, might be considered as an early diagnostic sign of forming of placental insufficiency, which is later realized as IUGR.


2018 ◽  
pp. 184-195
Author(s):  
Minh Son Pham ◽  
Vu Quoc Huy Nguyen ◽  
Dinh Vinh Tran

Small for gestational age (SGA) and fetal growth restriction (FGR) is difficult to define exactly. In this pregnancy condition, the fetus does not reach its biological growth potential as a consequence of impaired placental function, which may be because of a variety of factors. Fetuses with FGR are at risk for perinatal morbidity and mortality, and poor long-term health outcomes, such as impaired neurological and cognitive development, and cardiovascular and endocrine diseases in adulthood. At present no gold standard for the diagnosis of SGA/FGR exists. The first aim of this review is to: summarize areas of consensus and controversy between recently published national guidelines on small for gestational age or fetal growth restriction; highlight any recent evidence that should be incorporated into existing guidelines. Another aim to summary a number of interventions which are being developed or coming through to clinical trial in an attempt to improve fetal growth in placental insufficiency. Key words: fetal growth restriction (FGR), Small for gestational age (SGA)


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