scholarly journals Micronutrients: Its role in intrauterine growth restriction

1970 ◽  
Vol 1 (2) ◽  
pp. 77-82
Author(s):  
Swaraj Rajbhandari ◽  
Sanu Maiya Dali
Keyword(s):  
Developing Countries ◽  
Key Words ◽  
Fetal Growth ◽  
Intrauterine Growth Restriction ◽  
Perinatal Outcomes ◽  
Favourable Outcome ◽  
Growth Restriction ◽  
Intrauterine Growth ◽  
Public Health Officials ◽  
Energy Supplementation

Objective: To find out the role of micronutrients in intrauterine growth restrictions. Methodology. Desktop review of articles from the year 1986 till 2005 March using key words, Micronutrients AND Intrauterine Growth Restriction. Results: 13.7 million infants are born annually with fetal growth restriction (IUGR) comprising 11% of all births in developing countries affecting up to 40% in some of developing countries varying from 14-38.8% for Nepal. Public health officials have recognized the urgent need for interventions aimed to prevent IUGR as this higher percent is likely due to protein calorie malnutrition, kwown to be the second leading cause of perinatal morbidity and mortality. The identification of IUGR is crucial because proper evaluation and management can result in a favourable outcome. Sixty five percent of IUGR are not identified until after delivery. More over, it is unrealistic issue to assume that extra nutrient taken for few months during pregnancy would replace the under nutrition that has been prevalent for over decades in terms of reproductive performance. Conclusion: Although it is frustrating that, most of the interventions aimed to prevent or treat impaired fetal growth have hardly shown any beneficial effect on short-term perinatal outcomes, long term benefit may be rewarding with significant impact. Hence provision of energy supplementation for two (or more, if they occur) consecutive pregnancies must be focused rather than during single pregnancy. Key words: micronutrients, intrauterine growth restriction, malnutrion. doi:10.3126/njog.v1i2.2407 N. J. Obstet. Gynaecol Vol. 1, No. 2, p. 77-82 Nov-Dec 2006

Comparison of perinatal outcomes between patients with suspected complex and simple gastroschisis

2021 ◽  
Author(s):  
Virginia Medina Jiménez ◽  
Sandra Acevedo-Gallegos ◽  
Monica Aguinaga Rios ◽  
Juan Manuel Gallardo-Gaona
Keyword(s):  
Abdominal Wall ◽  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
Intrauterine Growth Restriction ◽  
Primary Outcome ◽  
Perinatal Outcomes ◽  
Growth Restriction ◽  
Tertiary Referral Center ◽  
Intrauterine Growth ◽  
Bowel Dilatation

Objective: The aim of this study was to compare perinatal outcomes between patients with and without prenatal ultrasound markers predictive of complex gastroschisis. Method: A prospective cohort of 98 patients with isolated fetal gastroschisis underwent antenatal ultrasound and delivered in a tertiary referral center. Patients were classified according to eight ultrasonographic markers predictive of complexity, and perinatal outcomes were assessed accordingly. The primary outcome was the presence of fetal growth restriction and staged SILO reduction postnatally. Results: Of all fetuses, 54.1% (n = 53) displayed ultrasonographic markers predictive of complexity at 32.7 ± 4.3 weeks of gestation. Gastric dilatation was the most frequent marker followed by extra-abdominal bowel dilatation. The presence of ultrasound markers predictive of complexity, was not associated with intrauterine growth restriction but its absence was less associated with staged SILO reduction of the abdominal wall postnatally with a RR of 0.79 (CI95% 0.17-0.53) Conclusion: Fetuses with ultrasound markers that predict complexity were not associated with fetal growth restriction but its absence was less associated with staged SILO reduction of the abdominal wall postnatally. It is necessary to unify criteria, establish cut-off points and the optimal moment to measure these markers.

scholarly journals PERINATAL OUTCOMES AND LONG-TERM EFFECTS OF FETAL GROWTH RESTRICTION

2012 ◽  
Vol 61 (6) ◽  
pp. 68-75 ◽  
Author(s):  
Natalya Vladimirovna Artymuk ◽  
Aleksey Gennadyevich Trishkin ◽  
Ekaterina Sergeevna Bikmetova
Keyword(s):  
High Risk ◽  
Fetal Growth ◽  
Intrauterine Growth Restriction ◽  
Perinatal Outcomes ◽  
Growth Restriction ◽  
Fetal Life ◽  
Long Term Effects ◽  
Intrauterine Growth ◽  
Effects On Children

The article presents a review of sources concerning perinatal outcomes and long-term effects on children and adults born with intrauterine growth restriction (IUGR). Neonates with IUGR are at high risk for morbidity and mortality. The conditions of antenatal fetal life may program the range of unfavorable long-term effects in adulthood. This requires further study of the etiology, pathogenesis, diagnosis, and management of IUGR.

scholarly journals Maternal and perinatal outcomes of hyperthyroidsm in pregnancy at Dr. Cipto Mangunkusumo Hospital, Jakarta, period of January 2015 - December 2016

2021 ◽  
Vol 29 (1) ◽  
pp. 36
Author(s):  
Fita Maulina ◽  
M Adya F F Dilmy ◽  
Ali Sungkar
Keyword(s):  
Pregnant Women ◽  
Preterm Delivery ◽  
Intrauterine Growth Restriction ◽  
Fetal Death ◽  
Perinatal Outcomes ◽  
Growth Restriction ◽  
Intrauterine Fetal Death ◽  
Adequate Treatment ◽  
Intrauterine Growth ◽  
In Pregnancy

Objectives: To report maternal and perinatal outcomes of hyperthyroidsm in pregnancy.Case Report: There were 3622 cases of delivering pregnant women during the period of the study. From this number, the prevalence of pregnant women with hyperthyroid was 0.2 %. We reported 9 cases of hyperthyroid in pregnancy. The number of pregnancy complication and outcome on pregnant women with hyperthyroidism were preterm labor (44%) and preeclampsia (22%), both were found in group of mother who did taking antihyperthyroid therapy. In those who did not take antihyperthyroid therapy 11% had spontaneous abortion and 11% had preterm delivery. Fetal complications were intrauterine growth restriction (11%) and intrauterine fetal death (23%), both of these complication were on the group who did not take antihyperthyroid. On the contrary, 44% babies were born with normal birthweight in group who took antihyperthyroid.Conclusion: There were differences noted between the group that took adequate treatment and the group that did not take antihyperthyroid. The incidence of intrauterine growth restriction and intrauterine fetal death were high in group that did not took antihyperthyroid therapy but the incidence of preterm delivery as the maternal complication was high in group that did take the antihyperthyroid therapy.  

Relationship between abnormal fetal testing and adverse perinatal outcomes in intrauterine growth restriction

2007 ◽  
Vol 196 (5) ◽  
pp. e48-e51 ◽  
Author(s):  
Juan M. Gonzalez ◽  
David M. Stamilio ◽  
Serdar Ural ◽  
George A. Macones ◽  
Anthony O. Odibo
Keyword(s):  
Intrauterine Growth Restriction ◽  
Perinatal Outcomes ◽  
Growth Restriction ◽  
Intrauterine Growth ◽  
Adverse Perinatal Outcomes

Placental elasticity assessment by point shear wave elastography in pregnancies with intrauterine growth restriction

2019 ◽  
Vol 47 (8) ◽  
pp. 841-846 ◽  
Author(s):  
Murat Akbas ◽  
Faik M. Koyuncu ◽  
Burcu Artunç-Ulkumen
Keyword(s):  
Pregnant Women ◽  
Shear Wave ◽  
Intrauterine Growth Restriction ◽  
Perinatal Outcomes ◽  
Shear Wave Elastography ◽  
Growth Restriction ◽  
Intrauterine Growth ◽  
The Mean ◽  
Adverse Perinatal Outcomes ◽  
Doppler Indices

Abstract Background Placental elasticity varies in different diseases. Our objective was to evaluate placental elasticity using point shear wave elastography (pSWE) in pregnancies with intrauterine growth restriction (IUGR). Methods A total of 66 pregnant women with IUGR and 81 healthy pregnant women were enrolled. Placental elasticity was measured using the transabdominal pSWE method. Ten measurements were made, and the mean was accepted as the mean placental elasticity value in each case. The results for IUGR pregnancies and controls were compared. Results The mean pSWE values were significantly higher in pregnancies with IUGR, which means that women with IUGR have stiffer placentas (P < 0.001). Furthermore, the pSWE values were significantly and positively correlated with Doppler indices and adverse perinatal outcomes. Conclusion The pregnancies with IUGR had stiffer placentas than the healthy controls. The utilization of pSWE for placental elasticity may be useful in the diagnosis and management of IUGR as a supplement to the existing ultrasonography methods.

Placental expression of the obesity-associated gene FTO is reduced by fetal growth restriction but not by macrosomia in rats and humans

2012 ◽  
Vol 4 (2) ◽  
pp. 134-138 ◽  
Author(s):  
S. Mayeur ◽  
O. Cisse ◽  
A. Gabory ◽  
S. Barbaux ◽  
D. Vaiman ◽  
...  
Keyword(s):  
Weight Gain ◽  
Birth Weight ◽  
Fetal Growth ◽  
Genetic Variants ◽  
Intrauterine Growth Restriction ◽  
Growth Restriction ◽  
Intrauterine Growth ◽  
Placental Villi ◽  
Insight Into ◽  
Epigenetic Processes

Genetic variants in the FTO (fat mass- and obesity-associated) gene have the highest association of all obesity-associated genes. Its placental expression was shown to relate to birth weight, suggesting that it may participate in the control of fetal weight gain. To gain more insight into the implication of FTO in fetal growth, we measured its placental expression in samples including extremes of abnormal fetal growth, such as after intrauterine growth restriction (IUGR) or macrosomia in both rats and humans. In rats, fetal growth was modulated by maternal nutritional modifications. In humans, placental villi were collected from pathological pregnancies (i.e. with IUGR or fetal macrosomia). Placental FTO mRNA expression was reduced by IUGR but was not significantly affected by macrosomia in either rats or humans. Our data suggest that placental FTO may participate in interactions between the in utero environment and the control of fetal growth under IUGR conditions by modulating epigenetic processes.

Dichorionic Twins Discordant for Massive Perivillous Fibrinoid Deposition: Report of a Case and Review of the Literature

2017 ◽  
Vol 26 (1) ◽  
pp. 41-46 ◽  
Author(s):  
Ona Faye-Petersen ◽  
Adrienne Sauder ◽  
Ydamis Estrella ◽  
Debra S. Heller
Keyword(s):  
Intrauterine Growth Restriction ◽  
Pregnancy Loss ◽  
Perinatal Outcomes ◽  
Growth Restriction ◽  
Unknown Etiology ◽  
Dizygotic Twin ◽  
Review Of The Literature ◽  
Supportive Evidence ◽  
Intrauterine Growth ◽  
Immune Mediated

Massive perivillous fibrinoid deposition (MFD) and maternal floor infarction (MFI) are lesions of unknown etiology associated with poor perinatal outcomes, including fetal intrauterine growth restriction and neurodevelopmental injury, high risks of pregnancy loss, and recurrence in subsequent gestations. MFI comprises massive intervillous fibrinoid deposition concentrated at the maternal floor. MFD is a similar lesion but is diffuse within the parenchyma. MFD/MFI lesions represent a spectrum of severity of cloak-like perivillous fibrinoid deposition, and there is mounting evidence that, often, they represent sequelae of immune-mediated phenomena and/or an imbalance in factors that normally maintain the fluidity of blood in the maternal space. There are only a handful of reported instances of discordant MFD/MFI occurrence in twin placentas. We present a fourth such occurrence in a fused, dichorionic diamniotic twin placenta and submit that our dizygotic twin gestation case provides additional supportive evidence that immune-mediated mechanisms are involved in the formation of pathological accumulations of fibrinoid, at least in some cases.

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