Room Temperature, Metal-Free, Regio-Selective Arylselenation of Anilines Using Diselenides as Selenium Source

Synthesis ◽  
2022 ◽  
Author(s):  
Rekha Bai ◽  
Kamlesh Kumar Dabaria ◽  
Satpal Singh Badsara
Keyword(s):  
Ambient Temperature ◽  
Room Temperature ◽  
Bond Formation ◽  
Metal Free ◽  
Aniline Derivatives

A metal-free direct C-H selenation of aniline derivatives via an iodine catalysed C-Se bond formation using diselenides as a selenium source at ambient temperature is described. A variety of aniline derivatives underwent regio-selective C-H selenation with different diselenides to afford the corresponding aryl selenoethers in good to excellent yields.

Metal-free regioselective C–H chalcogenylation of coumarins/(hetero)arenes at ambient temperature

2020 ◽  
Vol 56 (12) ◽  
pp. 1847-1850
Author(s):  
Zengqiang Song ◽  
Chaochao Ding ◽  
Shaoli Wang ◽  
Qian Dai ◽  
Yaoguang Sheng ◽  
...  
Keyword(s):  
Ambient Temperature ◽  
Room Temperature ◽  
Practical Method ◽  
Metal Free

A novel and practical method for the direct regioselective chalcogenylation of coumarins at the C3-postion and selenation of other (hetero)arenes has been achieved using PIFA as a promoter at room temperature.

An Iodide-Mediated Transition-Metal-Free Strategy towards Unsymmetrical Diaryl Sulfides via Arylhydrazines and Thiols

Synthesis ◽  
2019 ◽  
Vol 52 (05) ◽  
pp. 727-734 ◽  
Author(s):  
Farnaz Jafarpour ◽  
Mohammad Asadpour ◽  
Meysam Azizzade ◽  
Mehran Ghasemi ◽  
Saideh Rajai-Daryasarei
Keyword(s):  
Transition Metal ◽  
Room Temperature ◽  
Bond Formation ◽  
Antidepressant Drug ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Potential Utility ◽  
Metal Free ◽  
Cross Coupling Reaction ◽  
High Yields

A mild, scalable iodine-mediated oxidative cross-coupling reaction of arylhydrazines and thiols for construction of thioethers (sulfides) in the absence of any transition metals or photocatalysts is disclosed. A variety of unsymmetrical diaryl sulfides with broad substrate scope both on thiols and hydrazines were synthesized in high yields in water at room temperature. Furthermore, to demonstrate the utility of the protocol, the above C–S bond formation was applied in the synthesis of the key structure of vortioxetine as an antidepressant drug. The gram-scale outcome also added to the potential utility of this protocol.

Oxidative organophotoredox catalysis: a regioselective synthesis of 2-nitro substituted imidazopyridines and 3-substituted indoles, initiated by visible light

2016 ◽  
Vol 40 (11) ◽  
pp. 9694-9701 ◽  
Author(s):  
Snehlata Yadav ◽  
Madhulika Srivastava ◽  
Pratibha Rai ◽  
Bhartendu Pati Tripathi ◽  
Anu Mishra ◽  
...  
Keyword(s):  
Visible Light ◽  
Visible Light Irradiation ◽  
Room Temperature ◽  
Bond Formation ◽  
Light Irradiation ◽  
Regioselective Synthesis ◽  
Metal Free

Intramolecular C–N heterocyclization and C–C bond formation under visible light irradiation at room temperature was accomplished with a metal-free photoredox catalyst.

3,6-Di(pyridin-2-yl)-1,2,4,5-tetrazine (pytz) catalysed metal-free amide bond formation from thioacids and amines at room temperature

2020 ◽  
Vol 61 (35) ◽  
pp. 152272
Author(s):  
Suvendu Samanta ◽  
Shounak Ray ◽  
Samanka Narayan Bhaduri ◽  
Partha Kumar Samanta ◽  
Papu Biswas
Keyword(s):  
Room Temperature ◽  
Bond Formation ◽  
Amide Bond ◽  
Metal Free ◽  
Amide Bond Formation

Visible-light-driven metal-free aerobic synthesis of highly diastereoselective phosphinoylpyrroloindoles

2020 ◽  
Vol 18 (7) ◽  
pp. 1354-1358 ◽  
Author(s):  
Ramesh Gorre ◽  
Damodar Enagandhula ◽  
Sridhar Balasubramanian ◽  
Srirama Murthy Akondi
Keyword(s):  
Visible Light ◽  
Room Temperature ◽  
Bond Formation ◽  
Metal Free ◽  
Visible Light Driven

A tandem C–P and C–C bond formation promoted by visible light at room temperature in a highly diastereoselective manner is described.

Sulfonamide formation from sodium sulfinates and amines or ammonia under metal-free conditions at ambient temperature

2015 ◽  
Vol 17 (3) ◽  
pp. 1395-1399 ◽  
Author(s):  
Kai Yang ◽  
Miaolin Ke ◽  
Yuanguang Lin ◽  
Qiuling Song
Keyword(s):  
Ambient Temperature ◽  
Efficient Method ◽  
Room Temperature ◽  
Metal Base ◽  
Metal Free ◽  
Highly Efficient ◽  
Reaction Proceeds

A practical and highly efficient method for the construction of a variety of sulfonamides mediated by I2 was demonstrated. The reaction proceeds readily at room temperature using a variety of sodium sulfinates and amines or ammonia in water in a metal-, base-, ligand-, or additive-free protocol. Primary, secondary and tertiary sulfonamides were obtained in good to excellent yields with a broad range of substrate tolerability.

scholarly journals A new face of phenalenyl-based radicals in the transition metal-free C–H arylation of heteroarenes at room temperature: trapping the radical initiator via C–C σ-bond formation

2017 ◽  
Vol 8 (11) ◽  
pp. 7798-7806 ◽  
Author(s):  
Jasimuddin Ahmed ◽  
Sreejyothi P ◽  
Gonela Vijaykumar ◽  
Anex Jose ◽  
Manthan Raj ◽  
...  
Keyword(s):  
Transition Metal ◽  
Room Temperature ◽  
Bond Formation ◽  
Metal Free ◽  
Radical Initiator

The first transition metal-free catalyzed direct C–H arylation of a variety of heteroarenes at room temperature has been reported using a phenalenyl-based radical without employing any photoactivation step.

Formation of Dislocation Channels in Neutron Irradiated Molybdenum

1972 ◽  
Vol 30 ◽  
pp. 672-673
Author(s):  
S. Mahajan
Keyword(s):  
Electron Microscopy ◽  
Transmission Electron Microscopy ◽  
Ambient Temperature ◽  
Room Temperature ◽  
Channel Formation ◽  
Early Stages ◽  
Transmission Electron ◽  
Three Stages ◽  
Two Stages ◽  
Polycrystalline Molybdenum

The evolution of dislocation channels in irradiated metals during deformation can be envisaged to occur in three stages: (i) formation of embryonic cluster free regions, (ii) growth of these regions into microscopically observable channels and (iii) termination of their growth due to the accumulation of dislocation damage. The first two stages are particularly intriguing, and we have attempted to follow the early stages of channel formation in polycrystalline molybdenum, irradiated to 5×1019 n. cm−2 (E > 1 Mev) at the reactor ambient temperature (∼ 60°C), using transmission electron microscopy. The irradiated samples were strained, at room temperature, up to the macroscopic yield point.Figure 1 illustrates the early stages of channel formation. The observations suggest that the cluster free regions, such as A, B and C, form in isolated packets, which could subsequently link-up to evolve a channel.

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