Highly efficient, sensitive and selective molecular screening of acetylcholinesterase inhibitors of natural origin by SPE-LC/ESI-TOF-MS and novel TLC-based bioauthography

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
T Mroczek ◽  
K Głowniak
Keyword(s):  
Acetylcholinesterase Inhibitors ◽  
Molecular Screening ◽  
Natural Origin ◽  
Highly Efficient ◽  
Tof Ms

scholarly journals Comprehensive 2D Gas Chromatography with TOF-MS Detection Confirms the Matchless Discriminatory Power of Monoterpenes and Provides In-Depth Volatile Profile Information for Highly Efficient White Wine Varietal Differentiation

Foods ◽  
2020 ◽  
Vol 9 (12) ◽  
pp. 1787
Author(s):  
Igor Lukić ◽  
Silvia Carlin ◽  
Urska Vrhovsek
Keyword(s):  
Gas Chromatography ◽  
Solid Phase ◽  
White Wine ◽  
Volatile Profile ◽  
Multivariate Statistical ◽  
Profile Information ◽  
Highly Efficient ◽  
Flight Mass Spectrometry ◽  
Sulfur Containing ◽  
Tof Ms

To differentiate white wines from Croatian indigenous varieties, volatile aroma compounds were isolated by headspace solid-phase microextraction (HS-SPME) and analyzed by comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry (GC×GC-TOF-MS) and conventional one-dimensional GC-MS. The data obtained were subjected to uni- and multivariate statistical analysis. The extra separation ability of the GC×GC second dimension provided additional in-depth volatile profile information, with more than 1000 compounds detected, while 350 were identified or tentatively identified in total by both techniques, which allowed highly efficient differentiation. A hundred and sixty one compounds in total were significantly different across monovarietal wines. Monoterpenic compounds, especially α-terpineol, followed by limonene and linalool, emerged as the most powerful differentiators, although particular compounds from other chemical classes were also shown to have notable discriminating ability. In general, Škrlet wine was the most abundant in monoterpenes, Malvazija istarska was dominant in terms of fermentation esters concentration, Pošip contained the highest levels of particular C13-norisoprenoids, benzenoids, acetates, and sulfur containing compounds, Kraljevina was characterized by the highest concentration of a tentatively identified terpene γ-dehydro-ar-himachalene, while Maraština wine did not have specific unambiguous markers. The presented approach could be practically applied to improve defining, understanding, managing, and marketing varietal typicity of monovarietal wines.

scholarly journals A ToF-MS with a Highly Efficient Electrostatic Ion Guide for Characterization of Ionic Liquid Electrospray Sources

2014 ◽  
Vol 25 (8) ◽  
pp. 1364-1373 ◽  
Author(s):  
Subha Chakraborty ◽  
Caglar Ataman ◽  
Daniel G. Courtney ◽  
Simon Dandavino ◽  
Herbert Shea
Keyword(s):  
Ionic Liquid ◽  
Highly Efficient ◽  
Ion Guide ◽  
Tof Ms

A graphene oxide-based immobilized PNGase F reagent for highly efficient N-glycan release and MALDI-TOF MS profiling

2014 ◽  
Vol 6 (8) ◽  
pp. 2518 ◽  
Author(s):  
Xiaojun Ren ◽  
Haihong Bai ◽  
Yiting Pan ◽  
Wei Tong ◽  
Peibin Qin ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Maldi Tof Ms ◽  
Highly Efficient ◽  
Maldi Tof ◽  
Pngase F ◽  
Tof Ms

Natural-Origin Hypocrellin-HSA Assembly for Highly Efficient NIR Light-Responsive Phototheranostics against Hypoxic Tumors

2019 ◽  
Vol 11 (48) ◽  
pp. 44989-44998 ◽  
Author(s):  
Chuangli Zhang ◽  
Jiasheng Wu ◽  
Weimin Liu ◽  
Xiuli Zheng ◽  
Pengfei Wang
Keyword(s):  
Natural Origin ◽  
Highly Efficient ◽  
Nir Light
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