All-trans retinoic acid co-administered with pegylated interferon and ribavirin does not influence viral kinetics in hepatitis C infected patients with previous non-response: Results of the ATRACTION study

M Schuchmann; JM Kittner; JF Schlaak; D Klaas; C Eisenbach; T Berg; C Trautwein; R Günther; S Zeuzem; R Goesseringer; A Ehrlich; K Neumann; D Wachtlin; WO Boecher; PR Galle

doi:10.1055/s-0031-1295936

All-trans retinoic acid co-administered with pegylated interferon and ribavirin does not influence viral kinetics in hepatitis C infected patients with previous non-response: Results of the ATRACTION study

Zeitschrift für Gastroenterologie ◽

10.1055/s-0031-1295936 ◽

2012 ◽

Vol 50 (01) ◽

Author(s):

M Schuchmann ◽

JM Kittner ◽

JF Schlaak ◽

D Klaas ◽

C Eisenbach ◽

...

Keyword(s):

Retinoic Acid ◽

Hepatitis C ◽

Pegylated Interferon ◽

Viral Kinetics ◽

Trans Retinoic Acid ◽

All Trans Retinoic Acid

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A randomised, open-label, multicentre, efficacy and safety study examining the effects on viral kinetics of all-trans retinoic acid (Tretinoin) (VESANOID®) in combination with pegylated interferon alpha-2a (PEGASYS®) and ribavirin (COPEGUS®) therapy in patients with genotype 1-chronic hepatitis C and non-response to a previous course of peg-interferon alpha/ribavirin combination (ATRACTION)

http://isrctn.org/> ◽

10.1186/isrctn00680126 ◽

2012 ◽

Author(s):

Marcus Schuchmann

Keyword(s):

Interferon Alpha ◽

Pegylated Interferon ◽

Efficacy And Safety ◽

Open Label ◽

Safety Study ◽

Viral Kinetics ◽

Pegylated Interferon Alpha ◽

Trans Retinoic Acid ◽

All Trans Retinoic Acid ◽

Kinetics Of

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Hepatitis C virus Core overcomes all-trans retinoic acid-induced apoptosis in human hepatoma cells by inhibiting p14 expression via DNA methylation

Oncotarget ◽

10.18632/oncotarget.20337 ◽

2017 ◽

Vol 8 (49) ◽

pp. 85584-85598 ◽

Cited By ~ 3

Author(s):

Juri Kwak ◽

Jung-Hye Choi ◽

Kyung Lib Jang

Keyword(s):

Dna Methylation ◽

Retinoic Acid ◽

Hepatitis C Virus ◽

Hepatitis C ◽

Human Hepatoma ◽

Human Hepatoma Cells ◽

Virus Core ◽

Trans Retinoic Acid ◽

All Trans Retinoic Acid ◽

Induced Apoptosis

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No beneficial effect of all-trans retinoic acid in previous non-responder patients with chronic hepatitis C: The ATRACTION study, a phase II randomised trial

Digestive and Liver Disease ◽

10.1016/j.dld.2012.11.006 ◽

2013 ◽

Vol 45 (4) ◽

pp. 323-329 ◽

Cited By ~ 4

Author(s):

Marcus Schuchmann ◽

Jens M. Kittner ◽

Jörg F. Schlaak ◽

Dietmar M. Klass ◽

Christoph Eisenbach ◽

...

Keyword(s):

Chronic Hepatitis ◽

Retinoic Acid ◽

Hepatitis C ◽

Beneficial Effect ◽

Chronic Hepatitis C ◽

Phase Ii ◽

Randomised Trial ◽

Trans Retinoic Acid ◽

All Trans Retinoic Acid

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All-trans retinoic acid for treatment of chronic hepatitis C

Liver International ◽

10.1111/j.1478-3231.2007.01666.x ◽

2008 ◽

Vol 28 (3) ◽

pp. 347-354 ◽

Cited By ~ 18

Author(s):

Wulf O. Böcher ◽

Christian Wallasch ◽

Thomas Höhler ◽

Peter R. Galle

Keyword(s):

Chronic Hepatitis ◽

Retinoic Acid ◽

Hepatitis C ◽

Chronic Hepatitis C ◽

Trans Retinoic Acid ◽

All Trans Retinoic Acid

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All-trans-Retinoic Acid for Treatment of Patients with Chronic Hepatitis C and Non-Response to Interferon-alfa/Ribavirin

Zeitschrift für Gastroenterologie ◽

10.1055/s-2005-862286 ◽

2005 ◽

Vol 43 (01) ◽

Author(s):

WO Böcher ◽

C Wallasch ◽

T Herget ◽

B Klebel ◽

P Galle

Keyword(s):

Chronic Hepatitis ◽

Retinoic Acid ◽

Hepatitis C ◽

Chronic Hepatitis C ◽

Interferon Alfa ◽

Trans Retinoic Acid ◽

All Trans Retinoic Acid

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W01.56 Gene profiling of the atherosclerotic lesion after all-trans retinoic acid exposure

Atherosclerosis ◽

10.1016/s0021-9150(04)90056-1 ◽

2004 ◽

Vol 5 (1) ◽

pp. 13

Author(s):

P OCAYA

Keyword(s):

Retinoic Acid ◽

Atherosclerotic Lesion ◽

Acid Exposure ◽

Gene Profiling ◽

Trans Retinoic Acid ◽

All Trans Retinoic Acid

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Antiproliferative effect of all-trans-retinoic acid in cholangiocarcinoma

10.1055/s-0037-1608140 ◽

2017 ◽

Author(s):

A Prawan ◽

S Butsri ◽

V Kukongviriyapan ◽

L Senggunprai ◽

S Kongpetch

Keyword(s):

Retinoic Acid ◽

Antiproliferative Effect ◽

Trans Retinoic Acid ◽

All Trans Retinoic Acid

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Response of Aldehyde Dehydrogenase (ALDH) after Cisplatin and All-Trans Retinoic Acid (ATRA) treatment of Spheroid-derived Cells (SDCs) from cervical cancer cell lines

10.1055/s-0038-1671355 ◽

2018 ◽

Cited By ~ 1

Author(s):

J Xu ◽

J Sehouli ◽

AM Kaufmann

Keyword(s):

Cervical Cancer ◽

Retinoic Acid ◽

Cell Lines ◽

Cancer Cell ◽

Aldehyde Dehydrogenase ◽

Cancer Cell Lines ◽

Cervical Cancer Cell ◽

Atra Treatment ◽

Trans Retinoic Acid ◽

All Trans Retinoic Acid

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Faculty Opinions recommendation of Vitamin A metabolite, all-trans-retinoic acid, mediates alternative splicing of protein kinase C deltaVIII (PKCdeltaVIII) isoform via splicing factor SC35.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.4015981.3779089 ◽

2010 ◽

Author(s):

Juan Valcárcel ◽

Sophie Bonnal

Keyword(s):

Protein Kinase C ◽

Retinoic Acid ◽

Alternative Splicing ◽

Protein Kinase ◽

Vitamin A ◽

Splicing Factor ◽

Kinase C ◽

Trans Retinoic Acid ◽

All Trans Retinoic Acid

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Faculty Opinions recommendation of All-trans-retinoic acid ameliorates hepatic steatosis in mice by a novel transcriptional cascade.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718367604.793495757 ◽

2014 ◽

Author(s):

Isao Sakaida ◽

Taro Takami

Keyword(s):

Retinoic Acid ◽

Hepatic Steatosis ◽

Trans Retinoic Acid ◽

All Trans Retinoic Acid

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