Management algorithm in newly diagnosed European moyamoya angiopathy: One year experience at the Moyamoya Center, University Children's Hospital Zurich

2013 ◽  
Vol 44 (02) ◽  
Author(s):  
N Khan ◽  
D Deanovic ◽  
M Hoelzle ◽  
I Scheer ◽  
M Hug ◽  
...  
2019 ◽  
Author(s):  
Martin Greta

BACKGROUND Tuberculosis is a widespread and in many cases a fatal, infectious disease caused by many strains of mycobacterium complex usually mycobacterium tuberculosis. It can affect any part of the body but mainly the lungs hence called pulmonary tuberculosis. Tuberculosis in children has been less of a public health priority in the recent years despite the fact that TB has been a major cause of childhood morbidity and mortality worldwide with difficulties in diagnosis. Data on trends of childhood TB is rarely in published literature hence need for this research which will help in publishing OBJECTIVE To establish the trends in TB among children aged 1-12 years and its management over a period of five years from 2011- 2015 at Arthur Davison children’s hospital in Ndola and also to determine the proportion of TB in these children and to establish the age group most affected by TB over the period of five years and lastly to assess the proportion of TB and HIV as a co-morbidity METHODS The study reviewed all records that were registered in the MOH TB register at ADH from 2011 to 2015 coming up with a total number of 483 TB records and these records had satisfied the inclusion and exclusion criteria. The data capturing tool was used to collect the data. RESULTS : This study determined the trends of TB in children aged 1 to 12 over the five years period from a total of 483 reviewed paediatric TB cases , its proportion in these children, the age range most affected by TB and lastly assessed TB and HIV as a co-morbidity at Arthur Davison Children’s hospital. It revealed that the trends were decreasing and that out of 483 TB patient, the majority 157(32.5%) of the TB patients were seen in the year 2011, followed by 129(26.7%), 84(17.4%), 57(11.8%) and 56(11.6%) representing the year 2012, 2013, 2014 and 2015 respectively. Findings on the age range most affected are that the majority 282(58.4%) of the TB patients were aged (5-12) years old while 201(41.6%) were aged between (1-5) years old. Therefore, the age range most affected by TB was between (5-12) years. The TB proportion results showed that Out of 483, the majority 467(96.7%) of the TB patient type were newly diagnosed, followed by 13(2.7%), 2(.4%) and the rest 1(.2%) that were Relapse, Trans-in and Treatment resumed respectively. And that many 467(96.7%) of TB condition types were PTB while 16(3.3%) were EPTB. Furthermore, the majority of 463(95.9%) were diagnosed by X-ray while 20(4.1%) were diagnosed by smear microscopy. And lastly In terms of HIV as a co-morbidity, the majority 175(36.2%) of the TB patients were HIV positive, followed by 173(35.8%) that were HIV negative while the rest 135(28%) of the TB patients were not tested for HIV CONCLUSIONS This study reports that the trends of TB in children aged 1-12 years have been decreasing from 2015 to 2011 .And the age range most affected was found to have been 5-12 years and the proportion of TB cases were mostly newly diagnosed and the diagnosis was made by use x-ray and lastly the large proportion of TB patients had tested positive for HIV as a co-morbidity. Therefore efforts should be made to sustain this decreasing trend of childhood TB.


2010 ◽  
Vol 17 (03) ◽  
pp. 464-471
Author(s):  
MUHAMMAD SALEEM ◽  
MUHAMMAD ASIF QURESHI ◽  
MUHAMMAD ASIF I QURESH

Empyema as a complication of community acquired pneumonia (CAP) is relatively common occurrence in developing countries. Study Design: Prospective study. Period: 4 year Jan 2001- Dec 2004. Setting: Department of Pediatric surgery the Children’s hospital Lahore. Patients & Method: A total of 114 cases of empyema thoracic secondary to CAP were dealt with during this period, while in the same duration a total of 1768 cases of pneumonia were treated at the Children’s hospital Lahore. Results: Majority of the patients with CAP (59.61%) were below one year of age whereas the patients who developed empyema, were mainly (45.67%) between 2 to 5 years of age. Patients above 5 years of age having CAP (31.70%) and having repeated attacks of respiratory tract infection were most susceptible to develop empyema. Staphylococcus aureus was the most common organism found (40.35%) in this series. Vaccination, poverty and gender did not significantaffected the development of empyema among the patients of CAP. Antibiotic resistance had no role in the development of empyema. Ibuprofen may be a risk factor. All the patients were initially managed with tube thoracostomy and antibiotics. Forty-eight patients (42.10%) needed subsequently operative management. Three patients (2.63%) had fatal course in this series same as seen in patients of CAP (2%). Conclusions: Immunization against causative organism and modification of out patient treatment may affect the incidence of empyema in children and should be studied prospectively.


2022 ◽  
Vol 4 (1) ◽  
pp. 2-3
Author(s):  
Amina Al Halwany ◽  
Hadir Hassouna ◽  
Yasmine El Chazli ◽  
Neveen Mikhael ◽  
Mohamed Abdelgalil

2021 ◽  
Vol 20 (1) ◽  
pp. 168-169
Author(s):  
M. Khalili ◽  
M. Gholamzadeh Baeis ◽  
M. Alaei

A 10-year-old boy known case of Gaucher disease about 2 years ago was admitted with nausea, vomiting and epigastric pain from 3 days before hospitalization to Mofid Children’s hospital, Tehran, Iran. On the initial examination, no abnormalities were found except for splenomegaly and brief tenderness on the spleen. In secondary paraclinical evaluations (with Ultrasound and Ct-scan), we noticed mesenteric lymphadenopathy in the patient. The lesions remained unchanged and no significant changes were observed in the clinical and laboratory evaluations of the patient during one-year follow-up period. This is a rare and benign manifestation of Gaucher disease, which is usually monitored and does not require any intervention without signs of malignancy or severe space occupying effects 


PEDIATRICS ◽  
1956 ◽  
Vol 18 (4) ◽  
pp. 682-685

The Adolescent Unit at the Children's Hospital, Boston, is now offering a general practice type of postgraduate training in the care of adolescents. One-year traineeships are available to a few properly qualified physicians who have had two or more years of hospital experience following graduation from Medical School. The teaching staff includes a gynecologist, endocrinologist, gastroenterologist, cardiologists, psychiatrists, etc., and is directed by Dr. J. R. Gallagher to whom any inquiries should be sent. A limited number of stipends are available.


PEDIATRICS ◽  
1978 ◽  
Vol 61 (6) ◽  
pp. 929-930
Author(s):  
John D. Lloyd-Still

Celiac disease is now a rare diagnosis in the United States. The incidence of celiac disease varies from 1 in 6,500 in Sweden1 to 1 in 890 in Switzerland.2 At the Melbourne Children's Hospital in Australia, Townley3 reported seeing 90 new patients with celiac disease in a four-year interval, with an almost equal incidence of newly diagnosed cases of celiac and cystic fibrosis per year. At the Children's Memorial Hospital in Chicago we now see 20 new cases of cystic fibrosis compared to three new celiac cases per year, despite performing intestinal biopsies in all suspected cases of celiac disease.


2021 ◽  
pp. 112067212199473
Author(s):  
David Gildea ◽  
Reinold Goetz ◽  
Richard Drew ◽  
Sarah Chamney

Objectives: The purpose of this study was to examine the aetiology, investigation and management of ophthalmia neonatorum (ON) presenting to a tertiary referral children’s hospital over 5 years. Methods: The eye swab data of all neonates presenting to Children’s Health Ireland at Temple Street (Dublin, Ireland) between 1st January 2013 and 3rd September 2018 was analysed. The medical records of all patients with positive eye swab results were retrospectively reviewed. Results: A total of 157 neonates had positive eye swab results. 54 cases were identified as ON. Chlamydia trachomatis (20.4%) was the most common organism identified, followed by Staphylococcus aureus (18.5%), Haemophilus influenzae (14.8%), Moraxella catarrhalis (7.4%), Streptococcus pneumoniae (5.6%), Escherischia coli (3.7%), Klebsiella pneumoniae (1.9%) and Pseudomonas aeruginosa (1.9%). A bacterial culture swab was tested in all cases (100%), a C. trachomatis/N. gonorrhoeae PCR swab in 70.4% and a viral PCR swab in 35.2%. On subanalysis of the cases that had C. trachomatis/N. gonorrhoeae PCR testing, C. trachomatis was responsible for 28.9% of cases. 50% of cases were hospitalised, intravenous antibiotics were administered in 46.3% and macrolide therapy was prescribed in 38.9%. Conclusions: C. trachomatis was the most common cause of ON in this study and may be responsible for an even higher proportion of cases due to incomplete testing. In keeping with studies in different populations, S. aureus, H. influenzae and S. pneumoniae were also common. As a result, an improved management algorithm for cases of ON has been introduced in this centre.


2018 ◽  
Vol 56 (5) ◽  
Author(s):  
Samia N. Naccache ◽  
Maryann Lustestica ◽  
Margil Fahit ◽  
Javier Mestas ◽  
Jennifer Dien Bard

ABSTRACTEarly establishment of infectious processes allows for expedited clinical management of meningitis and encephalitis. The FilmArray meningitis/encephalitis (FA-M/E) panel provides rapid detection of potential pathogens associated with encephalitis/meningitis in both immunocompetent and compromised patients. Here, we conducted a 1-year review of the performance of the FA-M/E panel at a tertiary care children's hospital. Two hundred sixty-five samples from 251 patients were tested. We found 87.25% (219/251) were negative, 9.96% (25/251) were positive for viral analytes, and 3.19% (8/251) were positive for bacterial analytes. When possible, positive results were confirmed by alternate testing; 4/6 available bacterial positives and 17/20 available viral positives were confirmed by retrospective culture or molecular testing.


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