Ophthalmia neonatorum in a tertiary referral children’s hospital: A retrospective study

2021 ◽  
pp. 112067212199473
Author(s):  
David Gildea ◽  
Reinold Goetz ◽  
Richard Drew ◽  
Sarah Chamney
Keyword(s):  
Medical Records ◽  
Moraxella Catarrhalis ◽  
Bacterial Culture ◽  
Tertiary Referral ◽  
Ophthalmia Neonatorum ◽  
Children's Hospital ◽  
Management Algorithm ◽  
Intravenous Antibiotics ◽  
Children’S Hospital ◽  
Different Populations

Objectives: The purpose of this study was to examine the aetiology, investigation and management of ophthalmia neonatorum (ON) presenting to a tertiary referral children’s hospital over 5 years. Methods: The eye swab data of all neonates presenting to Children’s Health Ireland at Temple Street (Dublin, Ireland) between 1st January 2013 and 3rd September 2018 was analysed. The medical records of all patients with positive eye swab results were retrospectively reviewed. Results: A total of 157 neonates had positive eye swab results. 54 cases were identified as ON. Chlamydia trachomatis (20.4%) was the most common organism identified, followed by Staphylococcus aureus (18.5%), Haemophilus influenzae (14.8%), Moraxella catarrhalis (7.4%), Streptococcus pneumoniae (5.6%), Escherischia coli (3.7%), Klebsiella pneumoniae (1.9%) and Pseudomonas aeruginosa (1.9%). A bacterial culture swab was tested in all cases (100%), a C. trachomatis/N. gonorrhoeae PCR swab in 70.4% and a viral PCR swab in 35.2%. On subanalysis of the cases that had C. trachomatis/N. gonorrhoeae PCR testing, C. trachomatis was responsible for 28.9% of cases. 50% of cases were hospitalised, intravenous antibiotics were administered in 46.3% and macrolide therapy was prescribed in 38.9%. Conclusions: C. trachomatis was the most common cause of ON in this study and may be responsible for an even higher proportion of cases due to incomplete testing. In keeping with studies in different populations, S. aureus, H. influenzae and S. pneumoniae were also common. As a result, an improved management algorithm for cases of ON has been introduced in this centre.

Effectiveness of early oseltamivir treatment in children with pandemic 2009 A/H1N1 influenza in the Vilnius University Children Hospital

2013 ◽  
Vol 19 (4) ◽  
pp. 459-465
Author(s):  
Vytautas Usonis ◽  
Irena Narkevičiūtė ◽  
Vilija Guntaitė
Keyword(s):  
Pandemic Influenza ◽  
Medical Records ◽  
H1n1 Influenza ◽  
The Other ◽  
Children's Hospital ◽  
Children’S Hospital ◽  
Vilnius University

Background. Oseltamivir is recommended for treatment of pandemic influenza in children. The therapy should be started as soon as possible, however, data on the effectiveness of such a treatment is rather limited. This study was accomplished in order to evaluate the effectiveness of oseltamivir depending on the time of the beginning of treatment. Materials and methods. Medical records of 72 children hospitalised to the Vilnius University Children’s Hospital (VUCH) because of laboratory confirmed pandemic influenza during November–December 2009 were analysed retrospectively. Duration of fever and frequency of complications in children treated with oseltamivir starting on days 1–2 and those who were started to treat ≥day 3 from the beginning of flu symptoms were compared to those who did not receive oseltamivir. Results. 40 patients were treated with oseltamivir: 20 children were commenced on treatment within 48 hours of their illness and the other 20 were started on oseltamivir on day 3 or later. 32 children were not treated with oseltamivir. Fever lasted 2.1 ± 0.8 days if the treatment with oseltamivir was started within 48 hours of illness and 4.1 ± 1.9 days if the treatment was started later (p 

scholarly journals THE REASONABLENESS OF USING DRUGS TO TREAT PNEUMONIA

2021 ◽  
Vol 62 (4) ◽  
Author(s):  
Nguyen Viet Dang ◽  
Tri Kim Ngoc ◽  
Bui Tung Hiep ◽  
Bui Dang Minh Tri
Keyword(s):  
Treatment Regimen ◽  
Medical Records ◽  
Initial Treatment ◽  
Descriptive Study ◽  
Antibiotic Regimen ◽  
Children's Hospital ◽  
Children’S Hospital ◽  
Antibiotic Dose ◽  
Very High ◽  
Antibiotic Delivery

Objective: To investigate the reasonableness of using drugs to treat pneumonia at Can Tho Children’s Hospital. Subjects and methods: a retrospective-descriptive study on 384 inpatient medical records at Can Tho Children’s Hospital from January 2019 to December 2019 was diagnosed pneumonia. Results: The percentage of the initial treatment regimen that was not reasonable with the recommended antibiotic regimen was relatively high at 84.11%. The proportion of antibiotics with inappropriate dose was only 1.71% of the total number of surveyed cases. The appropriate rate of antibiotic dose was 98.29%. The proportion of adjuvants with high appropriate doses such as Salbutamol, Hydrocortison and Prednisolon accounted for 100%. The rate of taking antibiotics in accordance with recommendations accounted for 94.67%. The rate of adjuvanvt drug delivery was very high, there were only a few cases that did not comply with recommendations such as Ibuprofen with 14 cases, accounting for 37.84%, Acetylcysteine ​​and Hydrocortison accounted for 14.58% with 7 cases, and Prednisolon and Budesonid accounted for the very low percentage. Conclusion: The proportion of the initial treatment regimen that was not compatible with the antibiotic regimen was relatively high. The appropriate rate of antibiotic dose was high. The proportion of adjuvants with suitable doses was high such as Salbutamol, Hydrocortison and Prednisolon. The antibiotic delivery rate was consistent with recommendations. The rate of adjuvant delivery was very high.

SURVEY ON THE USE OF CARBAPENEM ANTIBIOTICS AT CAN THO CHILDREN’S HOSPITAL

2021 ◽  
Vol 62 (6) ◽  
Author(s):  
Bui Dang Lan Huong ◽  
Bui Dang Minh Tri ◽  
Le Thi Kim Ngan
Keyword(s):  
Medical Records ◽  
Descriptive Study ◽  
Combination Regimen ◽  
Children's Hospital ◽  
Impaired Patient ◽  
Patient Status ◽  
Children’S Hospital ◽  
Combination Regimens ◽  
Alternative Regimen

Objective: To survey the use of carbapenem antibiotics at Can Tho Children’s Hospital. Objects and methods: Retrospective-descriptive study on 140 medical records of patients being treated at departments of Can Tho Children’s Hospital during the period from June 1st, 2020 to December 31st, 2020. Results: 26.43% of carbapenems were indicated empirically initiate, 73.57% of carbapenem was indicated in alternative regimens as the presence of microbiological results or worsened or impaired patient status. Carbapenem was mainly used in combination regimens. The proportion of the combination in the initiation regimen was 100%. In which, the proportion of combination regimen between carbapenem and an antibiotic (or vancomycin or gentamicin) was mainly. The rate of combination of three antibiotics was 18.9%. In the replacement regimen, the proportion of combination regimen was 79.6%. Of these, 57.3% of the carbapenem was combined with another antibiotic, most of which was combined with vancomycin. Combination regimen of three or four antibiotics accounted for a low percentage. Conclusion: 26.43% of carbapenem was indicated empirically initiate, 73.57% of carbapenem was indicated in an alternative regimen in the presence of microbiological results or worsened or impaired patient status. Carbapenem was mainly used in combination regimens.

The Implementation of Electronic Medical Records and Operation Room Performance in a Children’s Hospital

2014 ◽  
Vol 186 (2) ◽  
pp. 676
Author(s):  
H.O. Berdel ◽  
F. Davis ◽  
D. Moore ◽  
A. Qadeer ◽  
S. Gurley ◽  
...  
Keyword(s):  
Electronic Medical Records ◽  
Medical Records ◽  
Operation Room ◽  
Children's Hospital ◽  
Children’S Hospital

Efficacy and duration of propranolol therapy for pediatric parotid hemangiomas

2018 ◽  
pp. 1-5
Keyword(s):  
Electronic Medical Records ◽  
Retrospective Review ◽  
Medical Records ◽  
Pediatric Patients ◽  
Vascular Anomalies ◽  
Children's Hospital ◽  
Children’S Hospital ◽  
Anatomic Locations ◽  
Propranolol Therapy

Objective: To assess the efficacy and duration of propranolol therapy in pediatric patients with parotid hemangiomas, and compare the results with the efficacy and duration of propranolol therapy in patients with infantile hemangiomas in other anatomic locations. Methods: In this retrospective review, we analyzed the electronic medical records of 21 patients with parotid hemangiomas seen at the Children’s Hospital of Orange County’s Vascular Anomalies Clinic between 2009 and 2015. We compared the duration of propranolol therapy and rate of re-growth after completion of therapy with established data for these parameters in the literature for patients with other infantile hemangiomas. Results: In our cohort, 13 of the 21 patients had completed therapy, with a mean duration of 26 months of propranolol therapy. Eighteen patients (85.7%) were treated with the goal dose of propranolol (2 mg/kg/day). Three patients required a higher dose in order to achieve significant improvement in the size of the hemangioma. All patients had some response to propranolol. Eight of the 13 patients (61.5%) who completed propranolol therapy saw regrowth once initial propranolol therapy was either weaned or stopped. Conclusion: Pediatric patients with parotid hemangiomas require longer duration of propranolol therapy than patients with other infantile hemangiomas, and a greater percentage may have regrowth after completion of therapy.

Epidemiological Aspects of Childhood Poisonings in Ankara: A 10-Year Survey

1987 ◽  
Vol 6 (2) ◽  
pp. 147-152 ◽  
Author(s):  
F. Hincal ◽  
A.A. Hincal ◽  
Y. Müftü ◽  
F. Sarikayalar ◽  
Y. Özer ◽  
...  
Keyword(s):  
Retrospective Analysis ◽  
Medical Records ◽  
Information Service ◽  
Accidental Poisoning ◽  
Children's Hospital ◽  
Children’S Hospital ◽  
Medicinal Drugs ◽  
Overall Mortality ◽  
Children Under 5

1 In the 10-year period 1975-1984, 1188 children were admitted to the Children's Hospital of Hacettepe University in Ankara with a diagnosis of poisoning. 2 Retrospective analysis of their medical records showed that the incidence of poisoning with medicinal drugs was 64.0%, while pesticides accounted for 17.8% and plants for 6.7% of total cases. 3 The majority (69.9%) of cases were due to accidental poisoning, 70.6% of which occurred in children under 5 years of age; 15.1% of the poisonings were diagnosed as therapeutic mishaps of which 68.3% involved children under 5 years of age. 4 Analgesics (186 cases), barbiturates (176 cases) and tranquilizers (37 cases) were the most common drugs encountered, however, the two drugs most frequently overused were aspirin (146 cases) and Optalidon (175 cases). 5 Overall mortality was 4.9% (58 cases). Fifty per cent of fatalities were due to accidental poisoning while 41.4% (24 cases) were due to therapeutic mishaps. 6 This study is presented as a background to the need for the development of a Poison Information Service for Ankara.

scholarly journals SITUATION OF DRUGS FOR TREATMENT INTESTINAL INFECTION

2021 ◽  
Vol 62 (4) ◽  
Author(s):  
Lam Hoang Khanh ◽  
Nguyen Huu Phuc ◽  
Bui Tung Hiep ◽  
Bui Dang Minh Tri
Keyword(s):  
Medical Records ◽  
Pediatric Patients ◽  
Antibiotic Regimen ◽  
Intestinal Infection ◽  
Beta Lactam ◽  
Cross Sectional ◽  
Children's Hospital ◽  
Frequency Of Use ◽  
Children’S Hospital ◽  
Can Tho City

Objective: To survey the use of drugs to treat intestinal infection at Can Tho Children’s Hospital. Objects and methods: Cross-sectional retrospective descriptive study on 400 medical records of pediatric patients diagnosed with intestinal infection in Can Tho City Children’s Hospital in 2019. Result: There were 353 pediatric patients using rehydration and electrolytes measeurement, ORS with the highest frequency was 38.66%. The antibiotic with the highest frequency of use was the beta-lactam 3rd group. In which, Cefotaxim had the most use frequency. Single regimen of cefotaxim used the most with a frequency of 70.06%. Meanwhile, the antibiotic regimen cefotaxime combined with tobramycin was the highest in the combined regimen with 57.14%. Up to 70 cases changed the regimen due to ineffective results and 22 cases changed the regimen due to its effectiveness, reducing the amount of antibiotics. The first regimen with the highest frequency of change was the cefotaxim regimen with 33 cases. The 2nd regimens changed with the highest frequency were cefotaxim regimen and regimen of cefotaxim combined with tobramycin with 5 cases. The third change of regimen was mostly from combination antibiotic regimen to single regimen. Conclusion: Rehydration and electrolyte measures were mainly ORS. Antibiotics used mainly in the beta-lactam 3rd group, Cefotaxim had the highest frequency of use. Cefotaxim was used the most frequency in a single regimen. The antibiotic combined regimen between cefotaxime and tobramycin was the highest use in all combined regimens. Changing treatment regimen was mainly due to the ineffective effect.

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