Polyethylene glycol bowel preparation does not eliminate the risk of acute renal failure: a population-based case-crossover study

Endoscopy ◽  
2014 ◽  
Vol 46 (02) ◽  
pp. 109-109
Author(s):  
N. Choi ◽  
J. Lee ◽  
Y. Chang ◽  
S. Jung ◽  
Y. Kim ◽  
...  
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Polyethylene Glycol ◽  
Crossover Study ◽  
Bowel Preparation ◽  
Population Based ◽  
Case Crossover

Acute renal failure following oral sodium phosphate bowel preparation: a nationwide case-crossover study

Endoscopy ◽  
2014 ◽  
Vol 46 (06) ◽  
pp. 465-470 ◽  
Author(s):  
Nam-Kyong Choi ◽  
Joongyub Lee ◽  
Yoosoo Chang ◽  
Ye-Jee Kim ◽  
Ju-Young Kim ◽  
...  
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Crossover Study ◽  
Bowel Preparation ◽  
Sodium Phosphate ◽  
Case Crossover ◽  
Oral Sodium Phosphate ◽  
Oral Sodium

scholarly journals The Role of Stroke as a Trigger for Incident Venous Thromboembolism: Results from a Population-based Case-Crossover Study

TH Open ◽  
2019 ◽  
Vol 03 (01) ◽  
pp. e50-e57
Author(s):  
Vânia Morelli ◽  
Joakim Sejrup ◽  
Birgit Småbrekke ◽  
Ludvig Rinde ◽  
Gro Grimnes ◽  
...  
Keyword(s):  
Venous Thromboembolism ◽  
Acute Stroke ◽  
Crossover Study ◽  
Conditional Logistic Regression ◽  
Population Based ◽  
Red Blood Cell Transfusion ◽  
Odds Ratios ◽  
Case Crossover ◽  
Increased Risk

AbstractStroke is associated with a short-term increased risk of subsequent venous thromboembolism (VTE). It is unclear to what extent this association is mediated by stroke-related complications that are potential triggers for VTE, such as immobilization and infection. We aimed to investigate the role of acute stroke as a trigger for incident VTE while taking other concomitant VTE triggers into account. We conducted a population-based case-crossover study with 707 VTE patients. Triggers were registered during the 90 days before a VTE event (hazard period) and in four preceding 90-day control periods. Conditional logistic regression was used to estimate odds ratios with 95% confidence intervals (CIs) for VTE according to triggers. Stroke was registered in 30 of the 707 (4.2%) hazard periods and in 6 of the 2,828 (0.2%) control periods, resulting in a high risk of VTE, with odds ratios of 20.0 (95% CI: 8.3–48.1). After adjustments for immobilization and infection, odds ratios for VTE conferred by stroke were attenuated to 6.0 (95% CI: 1.6–22.1), and further to 4.0 (95% CI: 1.1–14.2) when other triggers (major surgery, red blood cell transfusion, trauma, and central venous catheter) were added to the regression model. A mediation analysis revealed that 67.8% of the total effect of stroke on VTE risk could be mediated through immobilization and infection. Analyses restricted to ischemic stroke yielded similar results. In conclusion, acute stroke was a trigger for VTE, and the association between stroke and VTE risk appeared to be largely mediated by immobilization and infection.

scholarly journals Acute infection as a trigger for incident venous thromboembolism: Results from a population-based case-crossover study

2017 ◽  
Vol 2 (1) ◽  
pp. 85-92 ◽  
Author(s):  
Gro Grimnes ◽  
Trond Isaksen ◽  
Y. I. G. Vladimir Tichelaar ◽  
Sigrid K. Braekkan ◽  
John-Bjarne Hansen
Keyword(s):  
Venous Thromboembolism ◽  
Crossover Study ◽  
Acute Infection ◽  
Population Based ◽  
Case Crossover

Genitourinary disease risks among 5-year ovarian cancer survivors in a population-based cohort study.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. 10073-10073
Author(s):  
Mia Hashibe ◽  
Yuji Chen ◽  
Brenna Blackburn ◽  
Yuan Wan ◽  
Kerry G. Rowe ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Renal Failure ◽  
Acute Renal Failure ◽  
Cancer Survivors ◽  
Cancer Diagnosis ◽  
Population Based ◽  
General Population Cohort ◽  
Disease Risks ◽  
After Cancer

10073 Background: In the US, there are approximately 235,200 ovarian cancer survivors today. Five-year survival for ovarian cancer has increased from 36% for women who were diagnosed in 1975-1977 to 46% for women diagnosed between 2005-2011. Long term follow-up studies among ovarian cancer survivors are uncommon and late effects have not been well characterized in a population-based cohort. Although genitourinary complications during treatment are well known, long term impacts need to be investigated. Methods: A total of 602 first primary invasive ovarian cancer cases diagnosed between 1996-2012 who survived for > 5 years were identified in the Utah Population Database and compared to a general population cohort of women. Genitourinary disease diagnoses were identified through ICD codes from hospital electronic medical records and statewide ambulatory surgery and inpatient data. Cox regression models were used to estimate hazard ratios for disease risks by time since cancer diagnosis with adjustments on matching factors, baseline BMI, baseline Charlson Comorbidity Index (CCI), and race. Results: The overall risk of genitourinary diseases for ovarian cancer patients in comparison to the general population cohort was 1.51 (95%CI = 1.30-1.74) 5-10 years after cancer diagnosis. Approximately 54.6% of ovarian cancer survivors were diagnosed with a genitourinary disease 5-10 years after cancer diagnosis. The most common genitourinary diseases among the ovarian cancer survivors were urinary tract infections (10.1%), acute renal failure (5.5%), and chronic kidney disease (4.4%). The greatest risks were observed for hydronephrosis (HR = 10.65, 95%CI = 3.68-30.80), pelvic peritoneal adhesions (HR = 5.81, 95%CI = 1.11-30.39), cystitis and urethritis (HR = 2.67, 95%CI = 1.21-6.38), and acute renal failure (HR = 2.30, 95%CI = 1.36-3.88). Conclusions: Ovarian cancer survivors experience increased risks of various genitourinary diseases in the 5-10 year period following cancer diagnosis. Understanding the multimorbidity trajectory among ovarian cancer survivors is of vital importance to improve their clinical care after cancer diagnosis and allow for increased attention to these potential late effects.

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