Severe vitamin B6 intoxication after inappropriate supplementation with micronutrients following bariatric surgery

2015 ◽  
Vol 122 (03) ◽  
Author(s):  
D Schulte ◽  
N Cupa ◽  
M Ahrens ◽  
M Laudes
2015 ◽  
Vol 69 (7) ◽  
pp. 862-863 ◽  
Author(s):  
N Cupa ◽  
D M Schulte ◽  
M Ahrens ◽  
S Schreiber ◽  
M Laudes
Keyword(s):  

2009 ◽  
Vol 2 ◽  
pp. CCRep.S3226 ◽  
Author(s):  
S. Richard-Devantoy ◽  
J.B. Garrέ ◽  
B. Gohier

Postoperative complications resulting from bariatric surgery can lead to severe vitamin-deficiency states. A patient who underwent bariatric bypass surgery and later developed Wernicke's encephalopathy prompted us to present her interesting case history for discussion. Although bariatric surgery is known to be a risk factor for Wernicke's encephalopathy, this diagnosis is only rarely evoked in the postoperative course. We recommend that the occurrence of digestive, psychiatric or neurological symptoms after bariatric surgery should suggest a thiamine deficiency that must be promptly assessed. Without waiting for the results, thiamine supplementation should be initiated.


2019 ◽  
Vol 7 ◽  
pp. 232470961988805 ◽  
Author(s):  
Lauren M. Lemieux ◽  
Vijaya Surampudi

Biliopancreatic diversion is a surgical procedure that causes weight loss via volume restriction and malabsorption. It is now rarely performed due to the risk of severe nutritional deficiencies including vitamin A. We report a case of severe vitamin A deficiency due to malabsorption from a biliopancreatic diversion procedure for weight loss. By the time the patient presented to our department, she had developed blindness refractory to parenteral vitamin A treatment. A unique feature of her case is the development of a rash with vitamin A injections. This reaction has only been reported in one case series of 3 patients in the published literature. Her case highlights the importance of vitamin deficiency screening in patients after bariatric surgery, and her skin reaction to the injections is a unique side effect that is not frequently observed.


CHEST Journal ◽  
2021 ◽  
Vol 160 (4) ◽  
pp. A2124
Author(s):  
Ro-Kaye Simmonds ◽  
Jason Lofters ◽  
Nia Flemming ◽  
Oluwafeyi Adedoyin ◽  
Jodi-Ann Smith ◽  
...  

Author(s):  
V.J. Montpetit ◽  
S. Dancea ◽  
L. Tryphonas ◽  
D.F. Clapin

Very large doses of pyridoxine (vitamin B6) are neurotoxic in humans, selectively affecting the peripheral sensory nerves. We have undertaken a study of the morphological and biochemical aspects of pyridoxine neurotoxicity in an animal model system. Early morphological changes in dorsal root ganglia (DRG) associated with pyridoxine megadoses include proliferation of neurofilaments, ribosomes, rough endoplasmic reticulum, and Golgi complexes. We present in this report evidence of the formation of unique aggregates of microtubules and membranes in the proximal processes of DRG which are induced by high levels of pyridoxine.


2006 ◽  
Vol 175 (4S) ◽  
pp. 493-494
Author(s):  
Jared M. Whitson ◽  
G. Bennett Stackhouse ◽  
Marshall L. Stoller

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