UV spectroscopy and chemometrics: A simple approach to herbal quality control

Planta Medica ◽  
2015 ◽  
Vol 81 (16) ◽  
Author(s):  
SH El-Ahmady ◽  
HA Gad ◽  
MM Al-Azizi
2018 ◽  
Vol 11 (06) ◽  
pp. 1850034
Author(s):  
Hongxia Huang ◽  
Yuanyuan Lv ◽  
Xiaoyi Sun ◽  
Shuangshuang Fu ◽  
Xuefang Lou ◽  
...  

A technique for the determination of tannin content in traditional Chinese medicine injections (TCMI) was developed based on ultraviolet (UV) spectroscopy. Chemometrics were used to construct a mathematical model of absorption spectrum and tannin reference content of Danshen and Guanxinning injections, and the model was verified and applied. The results showed that the established UV-based spectral partial least squares regression (PLS) tannin content model performed well with a correlation coefficient ([Formula: see text]) of 0.952, root mean square error of calibration (RMSEC) of 0.476[Formula: see text][Formula: see text]g/ml, root mean square error of validation (RMSEV) of 1.171[Formula: see text][Formula: see text]g/ml, and root mean square error of prediction (RMSEP) of 0.465[Formula: see text][Formula: see text]g/ml. Pattern recognition models using linear discriminant analysis (LDA) and [Formula: see text] nearest neighbor ([Formula: see text]-NN) classifiers based on UV spectrum could successfully classify different types of injections and different manufacturers. The established method to measure tannin content based on UV spectroscopy is simple, rapid and reliable and provides technical support for quality control of tannin in Chinese medicine injections.


2019 ◽  
Vol 14 (1) ◽  
Author(s):  
Mengmeng Sun ◽  
Shengpeng Wang ◽  
Yong Jing ◽  
Li Li ◽  
Min He ◽  
...  

Abstract Background Herbal materials are widely used as medicinal products, dietary supplements, food, and spices. With increased consumption, the safety, quality, and efficacy of herbal materials are becoming more relevant. The authenticity of herbal materials plays an important role in herbal quality control, and there is an urgent need to develop a simple, direct, objective, rapid, and inexpensive measurement tool for the identification of herbal materials for the purpose of quality control. Methods Delayed luminescence (DL) was used to measure authentic and counterfeit herbal materials. A hyperbolic function was used to extract four properties from the DL curves of the herbal materials. Statistical tools, including Student’s t test and Principal Component Analysis, were used to differentiate authentic and counterfeit herbal materials based on the DL properties. Results Our results showed that authentic and counterfeit herbal materials could be identified based on the DL properties as follows: (a) authentic versus counterfeit materials; (b) authentic versus adulterated materials; (c) authentic versus sulfur-fumigated materials; as well as (d) authentic versus dyed materials. Conclusion The simple, direct, rapid, and inexpensive measurements offered by DL potentially offer a novel technique for the identification of Chinese herbal materials. However, the establishment of a valid database will be the next step toward the possible application of this technique, which would contribute significantly to the development of a novel digital tool for the quality control of herbal materials.


2013 ◽  
Vol 24 (6) ◽  
pp. 550-555 ◽  
Author(s):  
Emmanuel Amukohe Shikanga ◽  
Alvaro M. Viljoen ◽  
Ilze Vermaak ◽  
Sandra Combrinck

1999 ◽  
Vol 33 (3) ◽  
pp. 717-724 ◽  
Author(s):  
Peter A. G. M. de Smet

Author(s):  
E. A. Kenik ◽  
J. Bentley

Cliff and Lorimer (1) have proposed a simple approach to thin foil x-ray analy sis based on the ratio of x-ray peak intensities. However, there are several experimental pitfalls which must be recognized in obtaining the desired x-ray intensities. Undesirable x-ray induced fluorescence of the specimen can result from various mechanisms and leads to x-ray intensities not characteristic of electron excitation and further results in incorrect intensity ratios.In measuring the x-ray intensity ratio for NiAl as a function of foil thickness, Zaluzec and Fraser (2) found the ratio was not constant for thicknesses where absorption could be neglected. They demonstrated that this effect originated from x-ray induced fluorescence by blocking the beam with lead foil. The primary x-rays arise in the illumination system and result in varying intensity ratios and a finite x-ray spectrum even when the specimen is not intercepting the electron beam, an ‘in-hole’ spectrum. We have developed a second technique for detecting x-ray induced fluorescence based on the magnitude of the ‘in-hole’ spectrum with different filament emission currents and condenser apertures.


2003 ◽  
Vol 118 (3) ◽  
pp. 193-196 ◽  
Author(s):  
Jeffrey W McKenna ◽  
Terry F Pechacek ◽  
Donna F Stroup

1971 ◽  
Vol 127 (1) ◽  
pp. 101-105 ◽  
Author(s):  
L. L. Weed

2004 ◽  
Vol 49 (4) ◽  
pp. 401-403
Author(s):  
Richard B. Makover

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