:
Oceans can play a major role in supplying life-saving medicines in the world in future. Although considerable
progress has been made in finding new medicines from marine sources, large efforts are still necessary to examine such
molecules for clinical applications. Xyloketals are an important group of natural products with various powerful and prominent bioactivities such as inhibition of acetylcholine esterase, antioxidant activity, inhibition of L-calcium channels, radicalscavenging behavior, suppression of cell proliferation, reduction of neonatal hypoxic-ischemic brain injury, etc. This review
describes the isolation and structural characterization of all xyloketal natural products giving major emphasis on their bioactivity.