scholarly journals Ewing's Sarcoma of the Cervical Spine

2017 ◽  
Vol 07 (02) ◽  
pp. 086-089
Author(s):  
Meenakshi Bhattacharjee ◽  
Winston Huh ◽  
Vandana Thapar ◽  
Paul Dahm
Keyword(s):  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Pediatric Population ◽  
Signs And Symptoms ◽  
Neck Mass ◽  
Neurological Deficits ◽  
Resonance Imaging ◽  
Neck Trauma ◽  
Motor Weakness ◽  
Posterior Neck

AbstractIn this article, we present the case of a 6-year-old female presented to the emergency department with progressive ascending motor weakness leading to cardiac arrest. The recent medical history included neck trauma 1 month prior to admission, 2 weeks of subjective fevers, and 1 day of urinary incontinence. After stabilization, and a review of the recent signs and symptoms, a magnetic resonance imaging of the neck revealed a posterior neck mass from C2 to T2. Neurosurgical removal of the mass was consistent with Ewing's sarcoma. Neck pain is a common presentation in the pediatric population, with the most common cause being traumatic. When coupled with neurological deficits, further studies are warranted to evaluate for organic causes.

scholarly journals A RARE CASE OF EWING’S SARCOMA OF THE THORACIC SPINE

2019 ◽  
pp. 92-97
Author(s):  
P. L. Andropova ◽  
P. V. Gavrilov ◽  
M. E. Makogonova ◽  
D. B. Malamashin
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Rare Case ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Early Recognition ◽  
Primary Lesion ◽  
Neurological Deficits ◽  
Resonance Imaging ◽  
Modern Methods

Ewing’s sarcoma is a malignant tumor, with an extremely aggressive growth pattern and a high risk of metastasis. In our work we demonstrated a case of primary lesion of Ewing’s sarcoma of the thoracic vertebra in a 10-year-old girl. Localization, in this situation, the tumor poses a serious threat to the development of neurological deficits, which is associated with a high need for early recognition of this neoplasia with the help of modern methods of radiation diagnosis (computed tomography and magnetic resonance imaging, SPECT).

Cervical extraskeletal Ewing's sarcoma: case report demonstrating radiological features and management

2007 ◽  
Vol 122 (9) ◽  
pp. 998-1001 ◽  
Author(s):  
S Ali ◽  
K MacKenzie ◽  
R Reid ◽  
G O'Neill ◽  
I Ganly
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Magnetic Resonance ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Neck Mass ◽  
Cervical Region ◽  
Resonance Imaging ◽  
Rare Tumour ◽  
Extraskeletal Ewing’S Sarcoma

AbstractBackground:Extraskeletal Ewing's sarcoma is a rare tumour of mesenchymal origin, which is histologically similar to primary osseous Ewing's sarcoma. The majority of cases have been reported in the lower limb and paravertebral region, with a few cases reported in the neck.Methods:We report a patient with extraskeletal Ewing's sarcoma presenting with a right-sided neck mass, vocal fold palsy and T1 nerve root involvement. The detection of characteristic features on computed tomography and magnetic resonance imaging scans, in conjunction with histological analysis, was required to make the diagnosis.Results:Radiological imaging demonstrated that the tumour was infiltrating through the neural exit foramina of the lower cervical nerve roots, with encasement of the vertebral artery. The patient was managed with combination chemotherapy for systemic control and irradiation for local control.Conclusion:Extraskeletal Ewing's sarcoma has a propensity to occur in a paravertebral location, being found rarely in the cervical region, and has a predilection to infiltrate through neural exit formina. Computed tomography and magnetic resonance imaging are helpful in the diagnosis of this rare tumour.

Extraskeletal Ewing’s sarcoma presenting as a neck mass - case report

ORL ro ◽  
2017 ◽  
Vol 2 (35) ◽  
pp. 24
Author(s):  
Daniel Mirea ◽  
Loredana Mitran ◽  
Daniela Safta ◽  
Cornelia Niţipir ◽  
Bogdan Mocanu ◽  
...  
Keyword(s):  
Case Report ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Neck Mass ◽  
Extraskeletal Ewing’S Sarcoma ◽  
Mass Case

Treatment of Patients Aged over 50 Years with Non-Osseous Ewing's Sarcoma Family Tumors: Five Cases and Review of Literature

2008 ◽  
Vol 94 (6) ◽  
pp. 809-812 ◽  
Author(s):  
Gil Bar-Sela ◽  
Avivit Peer ◽  
Shelly Rothschild ◽  
Nissim Haim
Keyword(s):  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Pediatric Population ◽  
Infectious Complications ◽  
Treatment Modalities ◽  
Review Of Literature ◽  
Poor Prognostic Factor ◽  
Treatment Delays ◽  
Chemotherapy Protocol ◽  
Dose Reductions

Background Most clinical trials on Ewing's sarcoma family of tumors include pediatric and adolescent populations, whereas clinical data on older patients are limited. Patients and Methods We report on 5 patients older than 50 years with a tumor of the Ewing's sarcoma family treated recently in our department. Results Myelosuppression and infectious complications were the main toxicity encountered. Major dose reductions and/or treatment delays were required in all 5 patients. One patient died of septic shock. Complete remission was achieved in the remaining 4 patients with the addition of different treatment modalities. One patient had lung metastasis 3 years after starting chemotherapy, and 3 patients have remained without evidence of recurrent disease for 1–6 years from the onset of chemotherapy. Conclusions There is no definite answer as to whether older age is a poor prognostic factor in patients with a tumor of the Ewing's sarcoma family. In our experience, patients over 50 poorly tolerated the standard chemotherapy protocol used in the pediatric population.

scholarly journals Tumor Vessel Development and Expansion in Ewing's Sarcoma: A Review of the Vasculogenesis Process and Clinical Trials with Vascular-Targeting Agents

Sarcoma ◽  
2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Keri S. Stewart ◽  
Eugenie S. Kleinerman
Keyword(s):  
Bone Marrow ◽  
Clinical Trials ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Pediatric Population ◽  
Vascular Supply ◽  
Molecular Regulation ◽  
Vascular Targeting ◽  
Tumor Vessel ◽  
Vessel Development

Ewing's sarcoma accounts for a disproportionately high portion of the overall pediatric mortality rate compared to its rare incidence in the pediatric population. Little progress has been made since the introduction of traditional chemotherapies, and understanding the biology of the tumor is critical for developing new therapies. Ewing's sarcomas rely on a functional vascular supply, which is formed by a combination of angiogenesis and vasculogenesis. Recent insights into the molecular regulation of bone marrow (BM) cell participation in vascular development have identified VEGF, SDF-1α, and DLL4 as critical players in the vasculogenesis process. Clinical trials using vascular targeting agents, specifically targeting VEGF or DLL4, are underway.

Ewing’s sarcoma/primitive neuroectodermal tumor of the prostate a case report and literature review

2013 ◽  
Vol 7 (5-6) ◽  
Author(s):  
Tao Wu ◽  
Tao Jin ◽  
Deyi Luo ◽  
Lin Chen ◽  
Xiang Li
Keyword(s):  
Primitive Neuroectodermal Tumor ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Transrectal Ultrasound ◽  
Neuroectodermal Tumor ◽  
Resonance Imaging ◽  
Mri Scan ◽  
Difficult Defecation ◽  
Magnetic Resonance Imaging Mri ◽  
Multiagent Chemotherapy

We present a case of Ewing’s sarcoma (ES) and primitive neuroectodermal tumor (PNET) of prostate. A 29-year-old male presented with difficult defecation and anus distention and was found on magnetic resonance imaging (MRI) scan of the pelvis to have a prostate tumor. A transrectal ultrasound guided needle biopsy confirmed the diagnosis. The patient underwent cystoprostatectomy and replacement ileocystoplasty and was followed by multiagent chemotherapy. PNET/EWS of the prostate is an extremely rare neoplasm. And the prognosis is very poor, so we should pay enough attention to the differential diagnosis and treatment.

scholarly journals Ewing's Sarcoma and Primary Osseous Lymphoma: Spectrum of Imaging Appearances

2019 ◽  
Vol 23 (01) ◽  
pp. 036-057 ◽  
Author(s):  
Olympia Papakonstantinou ◽  
Violeta Nikodinovska ◽  
Filip Vanhoenacker ◽  
Marc-André Weber
Keyword(s):  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Tumor Stroma ◽  
Conventional Radiography ◽  
Long Bone ◽  
Round Cell ◽  
Resonance Imaging ◽  
Tissue Component ◽  
Grade Ii ◽  
Hematoxylin And Eosin

Ewing's sarcoma (ES) is a rare, highly malignant anaplastic stem cell tumor. Histologically, the tumor consists of uniform densely packed small monomorphic cells with round nuclei. The typical appearance at hematoxylin and eosin (H&E) staining is small blue round cells without any matrix formation. On conventional radiography, ES typically presents as a permeative lesion in the diaphysis of a long bone in a child. A large soft tissue component is another characteristic feature, best depicted by magnetic resonance imaging.Primary osseous lymphomas are most commonly highly malignant B-cell lymphomas. At H&E histologic staining, the tumor stroma consists of diffuse round-cell infiltrates that resembles the appearance of ES. Although there is no typical imaging appearance of an osseous lymphoma, it should be considered in an adult presenting with a Lodwick grade II or III lesion in the metaphysis or diaphysis of a large long bone, the pelvis, or the vertebral column. Histologic confirmation is mandatory.

scholarly journals PICTORIAL REVIEW OF EXTRAOSSEOUS EWING’S TUMOUR: A SINGLE CENTER EXPERIENCE

2017 ◽  
Vol 3 (3) ◽  
Author(s):  
Muhammad Bilal Fayyaz ◽  
Imran Khalid Niazi ◽  
Amjad Iqbal
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Magnetic Resonance ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Post Treatment ◽  
Resonance Imaging ◽  
Primitive Neuroectodermal Tumour ◽  
Neuroectodermal Tumour ◽  
Number Of Patients

Purpose: Ewing’s family tumour is an extremely rare tumour, with annual incidence rates amongst Caucasian children <21 years being in the range of 2–3 cases per million in the U.S. There are mainly three subtypes including Ewing’s sarcoma (ES) of bone, extraosseous (EO) Ewing’s tumour and Peripheral primitive neuroectodermal tumour. Although extremely rare, this study represents a review of various types of cases and the significance of imaging including its baseline and post-treatment response radiological characteristics. There are a very few cases of EO ES in the current literature with variable spectrum of tumour site and their imaging characteristics.Materials and Methods: Electronic records were retrospectively reviewed from 1 May 2011 to 1 May 2016 with patients who were diagnosed as histologically proven ES. A number of patients, gender and base line computed tomography (CT)/magnetic resonance imaging findings for staging were reviewed.Results: A total of 568 patients with diagnosed ES were analysed, of which 15 patients had EO type of ES. Of these only 8 patients had baseline imaging available which included tumours arising from the occipital region, orbit, anterior mediastinum, anterior abdominal wall, mesentery, kidney, prostate gland and presacral region.Conclusion: EO ES is a rare entity and can involve a wide array of soft tissue organs. A cross-sectional imaging with CT and MR has a key role in pre- and post-treatment assessment.Key words: Computed tomography, Ewing’s sarcoma, extraosseous Ewing’s, magnetic resonance imaging, peripheral primitive neuroectodermal tumour

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