Absorption and Excretion of 3-Chloromercuri-2-Methoxypropylurea Labeled with Hg203
SummaryA method of preparation of Hg203-labelled 3-chloromercuri-2-methoxypropylurea is given. At the same time the solvent to be used in the chromatographic assay of its radioactive purity is indicated.The absorption and excretion of this compound was studied in rats.A maximum of activity was observed in the kidneys during the first six hours. Subsequently the activity in the kidneys decreased whereas it increased in the intestine. After the first week, the biological half life for the whole body was 8 days and for the kidneys approximately 28 days.A high percentage of the activity in the kidneys was ionic mercury.
1971 ◽
Vol 26
(1)
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pp. 13-20
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1964 ◽
Vol 19
(11)
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pp. 1032-1042
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2018 ◽
Vol 18
(07)
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pp. 1840019
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1960 ◽
Vol 198
(4)
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pp. 784-786
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