The Preparation of Control Blood for External Quality Assessment Programs in Oral Anticoagulant Control

1978 ◽  
Vol 39 (01) ◽  
pp. 210-214 ◽  
Author(s):  
C A van Dijk-Wierda ◽  
L P van Halem-Visser ◽  
R van der Hoeff-van Halem ◽  
E A Loeliger
Keyword(s):  
Quality Control ◽  
The Netherlands ◽  
Quality Assessment ◽  
Oral Anticoagulant ◽  
External Quality Assessment ◽  
External Quality Control ◽  
External Quality ◽  
Blood Samples ◽  
Anticoagulant Agents

SummaryA method is described for the preparation of blood samples differing in coagulability, now used for external quality control in The Netherlands by laboratories employing thrombotest for the assessment of oral anticoagulant agents.

scholarly journals SPIDIA-RNA: Second External Quality Assessment for the Pre-Analytical Phase of Blood Samples Used for RNA Based Analyses

PLoS ONE ◽  
2014 ◽  
Vol 9 (11) ◽  
pp. e112293 ◽  
Author(s):  
Francesca Malentacchi ◽  
Mario Pazzagli ◽  
Lisa Simi ◽  
Claudio Orlando ◽  
Ralf Wyrich ◽  
...  
Keyword(s):  
Quality Assessment ◽  
External Quality Assessment ◽  
External Quality ◽  
Blood Samples ◽  
Analytical Phase

scholarly journals External Quality Assessment in the Evaluation of Laboratory Performance of Faecal Culture

2017 ◽  
Vol 10 ◽  
pp. 117863611769125
Author(s):  
Salla J Kiiskinen ◽  
Tarja Ojanen ◽  
Yvonne Björkman ◽  
Harri Laitinen ◽  
Anja Siitonen
Keyword(s):  
Public Health ◽  
Quality Control ◽  
External Quality Assessment ◽  
False Negative ◽  
The Other ◽  
Epidemiological Surveillance ◽  
External Quality Control ◽  
External Quality ◽  
Faecal Culture

In Finland, all laboratories carrying out diagnostics of infectious diseases in humans are approved by the Regional State Administrative Agencies and are obligated to participate in External Quality Assurance rounds. Performance in these rounds is thought to reflect the quality of laboratory work. In the 6-year study period, 17 Finnish laboratories received 48 simulated faecal specimens for the culturing of diarrhoeal pathogens, yielding altogether 586 faecal culture External Quality Control specimens and 581 reports. The results were correct in 92% of all reports and in 67% of all specimens. False-negative Salmonella results were given for 2 of the 18 specimens, one with biochemically atypical Salmonella strain and the other with a low count of Salmonella cells. False-negative Shigella report was given for 6 of the 7 specimens in some participating laboratory. Detection of all common faecal pathogens is especially relevant to patient safety, public health, and epidemiological surveillance.

scholarly journals SPIDIA-RNA: First external quality assessment for the pre-analytical phase of blood samples used for RNA based analyses

Methods ◽  
2013 ◽  
Vol 59 (1) ◽  
pp. 20-31 ◽  
Author(s):  
M. Pazzagli ◽  
F. Malentacchi ◽  
L. Simi ◽  
C. Orlando ◽  
R. Wyrich ◽  
...  
Keyword(s):  
Quality Assessment ◽  
External Quality Assessment ◽  
External Quality ◽  
Blood Samples ◽  
Analytical Phase

Combi scheme: new combined internal/external quality-assessment scheme in The Netherlands

1991 ◽  
Vol 37 (7) ◽  
pp. 1196-1204 ◽  
Author(s):  
Herman Steigstra ◽  
Rob T Jansen ◽  
Henk Baadenhuijsen
Keyword(s):  
The Netherlands ◽  
Quality Assessment ◽  
Internal Control ◽  
External Quality Assessment ◽  
Clinical Chemistry ◽  
Laboratory Data ◽  
Data Communication ◽  
Professional Organization ◽  
Internal Quality ◽  
External Quality

Abstract The Dutch Foundation for Quality Assessment in Clinical Chemistry (SKZL) is the professional organization that conducts external quality-assessment schemes in The Netherlands. However, such schemes in fact assess the performance of the internal quality-control systems of the participating laboratories. In this paper we describe a new concept, relating the data for internal control materials with those for external samples and thereby leading to a combined external/internal scheme (Combi). The statistical principles underlying the Combi scheme are discussed and examples of the graphical presentation of the results are shown. Because the laboratory data are transmitted over the public telephone system to the computers of the SKZL, we also describe the principles of the data communication. At two-month intervals a statistical presentation is sent to all participants. The central database is updated daily with the received results, making possible an on-line consultation regarding the statistics of the accumulated findings of the control materials in use.

Second SPIDIA-DNA External Quality Assessment (EQA): Influence of pre-analytical phase of blood samples on genomic DNA quality

2016 ◽  
Vol 454 ◽  
pp. 10-14 ◽  
Author(s):  
Francesca Malentacchi ◽  
Sara Pizzamiglio ◽  
Hady Ibrahim-Gawel ◽  
Mario Pazzagli ◽  
Paolo Verderio ◽  
...  
Keyword(s):  
Quality Assessment ◽  
Genomic Dna ◽  
External Quality Assessment ◽  
External Quality ◽  
Blood Samples ◽  
Dna Quality ◽  
Analytical Phase

Experience in the netherlands with an external quality control and scoring system for clinical chemistry laboratories

1977 ◽  
Vol 74 (3) ◽  
pp. 191-201 ◽  
Author(s):  
A.P. Jansen ◽  
E.J. Van Kampen ◽  
B. Leijnse ◽  
C.A.M. Meijers ◽  
P.J.J. Van Munster
Keyword(s):  
Quality Control ◽  
The Netherlands ◽  
Scoring System ◽  
Clinical Chemistry ◽  
External Quality Control ◽  
External Quality ◽  
Chemistry Laboratories

Applicability of various quality-control sera to assay of high-density lipoprotein cholesterol.

1980 ◽  
Vol 26 (7) ◽  
pp. 903-907
Author(s):  
D G Bullock ◽  
T J Carter ◽  
S V Hughes
Keyword(s):  
Quality Control ◽  
High Density Lipoprotein ◽  
Quality Assessment ◽  
High Density Lipoprotein Cholesterol ◽  
External Quality Assessment ◽  
Density Lipoprotein ◽  
High Density ◽  
Lipoprotein Cholesterol ◽  
Internal Quality ◽  
External Quality

Abstract Effective internal quality control and external quality assessment of high-density lipoprotein cholesterol assay is made difficult by analyte instability, and the suitability of quality-control sera for this purpose has not been studied. We have therefore investigated the properties of 25 different control sera from 15 suppliers by estimating within-batch precision for the two precipitation procedures used most widely (phosphotungstate/Mg2+ and heparin/Mn2+ with enzymic measurement of cholesterol. Some sera had properties similar to those of fresh human serum, but others demonstrated poor precision for one or both procedures or contained apparent high-density lipoprotein cholesterol in unphysiological concentrations. A study of six sera indicated that between-batch precision was consistent with the within-batch findings. We found that eight of the 25 batches of quality-control serum we investigated may be used for internal quality control and external quality assessment of high-density lipoprotein cholesterol assay.

Analytical Performance of Ca 19.9, Ca 125 and Ca 15.3 Assays as Observed through an External Quality Assessment Program

1994 ◽  
Vol 9 (1) ◽  
pp. 43-47 ◽  
Author(s):  
G.C. Zucchelli ◽  
A. Pilo ◽  
M.R. Chiesa ◽  
S. Masini ◽  
A. Clerico
Keyword(s):  
Monoclonal Antibody ◽  
Quality Control ◽  
Quality Assessment ◽  
External Quality Assessment ◽  
Ca 125 ◽  
External Quality ◽  
Ca 15.3 ◽  
Assessment Program ◽  
Ca 19.9 ◽  
Control Samples

Immunoassays of the tumor markers CA 19.9, CA125 and CA 15.3 are generally acknowledged to be a useful tool in the management of cancer patients. As a consequence, many methods developed by different companies are now commercially available. However, discrepancies have been described in the results of marker determinations even when the same monoclonal antibody was used. An external quality assessment (EQA) was carried out; starting from 1989 about 110 laboratories participated; since December 1991 the program was linked with the interlaboratory program Oncocheck organized by the Service de Radiopharmacie et Radioanalyse, University of Lyon. At present more than 200 laboratories of many European countries are involved: cumulatively 47 quality control samples have been prepared and sent to the participants. This manuscript is a report on data collected for CA 19.9, CA 125, and CA 15.3.

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