Surgical Endoscopy: Future Directions

2018 ◽  
Vol 02 (04) ◽  
pp. 383-387
Author(s):  
Megan Sippey ◽  
Wanda Lam ◽  
Ahmed Ali ◽  
Jeffrey Marks

AbstractSince the introduction of the modern endoscope in 1957, numerous advances have been made in its use. The endoscope has transitioned from a primarily diagnostic tool at its inception, to now offering a plethora of therapeutic interventions including Natural Orifice Transluminal Endoscopic Surgery (NOTES). Advances in the endoscope, endoscopic imaging modalities, and therapeutic tools and platforms have contributed to recent, and upcoming, progression in NOTES. Current states of these advancements are reviewed.

2007 ◽  
Vol 21 (4) ◽  
pp. 681-683 ◽  
Author(s):  
Raymond P. Onders ◽  
Michael F. McGee ◽  
Jeffrey Marks ◽  
Amitabh Chak ◽  
Michael J. Rosen ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
João Moreira-Pinto ◽  
Aníbal Ferreira ◽  
Carla Rolanda ◽  
Jorge Correia-Pinto

The main goal of Natural Orifice Transluminal Endoscopic Surgery (NOTES) is performing surgery avoiding skin incisions. Theoretical advantages of NOTES include decreased postoperative pain, reduction/elimination of general anesthesia, improved cosmetic outcomes, elimination of skin incision-related complications such as wound infections and hernias, and increased overall patient satisfaction. Although various forms of port creation to accomplish thoracic NOTES procedures have been proposed, transesophageal NOTES has been shown to be the most reliable one. The evolution of endoscopic submucosal transesophageal access resulted in the development of per-oral endoscopic myotomy (POEM), which had a fast transition to clinical practice. The authors present a review of the current state of the art concerning transesophageal NOTES, looking at its potential for diagnostic and therapeutic interventions as well as the hurdles yet to be overcome.


2020 ◽  
Vol 26 ◽  
Author(s):  
Emir Muzurović ◽  
Zoja Stanković ◽  
Zlata Kovačević ◽  
Benida Šahmanović Škrijelj ◽  
Dimitri P Mikhailidis

: Diabetes mellitus (DM) is a chronic and complex metabolic disorder, and also an important cause of cardiovascular (CV) diseases (CVDs). Subclinical inflammation, observed in patients with type 2 DM (T2DM), cannot be considered the sole or primary cause of T2DM in the absence of classical risk factors, but it represents an important mechanism that serves as a bridge between primary causes of T2DM and its manifestation. Progress has been made in the identification of effective strategies to prevent or delay the onset of T2DM. It is important to identify those at increased risk for DM by using specific biomarkers. Inflammatory markers correlate with insulin resistance (IR) and glycoregulation in patients with DM. Also, several inflammatory markers have been shown to be useful in assessing the risk of developing DM and its complications. However, the intertwining of pathophysiological processes and the not-quite-specificity of inflammatory markers for certain clinical entities limits their practical use. In this review we consider the advantages and disadvantages of various inflammatory biomarkers of DM that have been investigated to date as well as possible future directions. Key features of such biomarkers should be high specificity, non-invasiveness and cost-effectiveness.


2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Priscilla Magno ◽  
Mouen A. Khashab ◽  
Manuel Mas ◽  
Samuel A. Giday ◽  
Jonathan M. Buscaglia ◽  
...  

Background. NOTES techniques allow transesophageal access to the mediastinum. The aim of this study was to assess the feasibility of transesophageal biopsy of thoracic vertebrae.Methods. Nonsurvival experiments on four 50-kg porcine animals were performed. Transesophageal access to the mediastinum was attained using submucosal tunneling technique.Results. The posterior mediastinum was successfully accessed and navigated in all animals. Vertebral bodies and intervertebral spaces were easily approached while avoiding damage to adjacent vessels. Bone biopsy was successfully performed without complications, but the hardness of bone tissue resulted in small and fragmented samples.Conclusions. Peroral transesophageal access into the posterior mediastinum and thoracic vertebral bone biopsy was feasible and safe. The proximity of the esophagus to the vertebral column provides close and direct access to the thoracic spine and opens up new ground for the performance of multilevel anterior spine procedures using NOTES techniques.


1987 ◽  
Vol 18 (2) ◽  
pp. 235-249 ◽  
Author(s):  
Karl L. Hutterer

The purpose of the present essay is not to present a history of Philippine archaeology; several preliminary attempts have been made in this regard which may be consulted. Rather, the aim of this paper is to pause for a moment and look across the landscape of Philippine archaeology to assess what has been accomplished to date, to ponder strength and weaknesses of the field at this time, and to consider future directions. Nevertheless, the shape of any landscape is the result of historical events and processes that need to be taken into account if we want to understand its present form and assess its future potential and development. Thus, it will be necessary to include in the following thoughts historical perspectives which will help to explain how and why certain concepts, methods and research practices arose in the context of Philippine archaeology and came to determine our picture of Philippine prehistory.


2007 ◽  
Vol 65 (5) ◽  
pp. AB293
Author(s):  
Marvin Ryou ◽  
Reina D. Pai ◽  
Derek G. Fong ◽  
Christopher C. Thompson

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