When Right Is on the Left (and Vice Versa): A Case Series of Glioma Patients with Reversed Lateralization of Cognitive Functions

2020 ◽  
Vol 81 (02) ◽  
pp. 138-146
Author(s):  
Emmanuel Mandonnet ◽  
Charles Mellerio ◽  
Marion Barberis ◽  
Isabelle Poisson ◽  
Johan Martijn Jansma ◽  
...  
Keyword(s):  
Cognitive Functions ◽  
Language Production ◽  
Case Series ◽  
Spatial Neglect ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Functional Sites ◽  
Spatial Consciousness ◽  
Dominant Activity ◽  
Selection Of

AbstractWe report a case series of four patients operated on for a glioma in awake conditions and in whom task-based functional magnetic resonance imaging (fMRI) demonstrated right-dominant activity during a language production task. Language functional sites were identified intraoperatively by electrical stimulations only in the patient with a right-sided lesion. Furthermore, the pre- or postoperative cognitive evaluations in the three patients operated on for a left-sided glioma revealed right spatial neglect and dysexecutive syndrome, hence demonstrating that, in patients with right-dominant activity on language fMRI, the left hemisphere is implicated in spatial consciousness and cognitive control. This study supports the interest of presurgical task-based language fMRI to identify patients with a reversed lateralization of cognitive functions and to make an adequate selection of the battery of intraoperative cognitive tasks to be monitored in those rare outliers.

scholarly journals Individual Brain Charting, a high-resolution fMRI dataset for cognitive mapping

2018 ◽  
Vol 5 (1) ◽  
Author(s):  
Ana Luísa Pinho ◽  
Alexis Amadon ◽  
Torsten Ruest ◽  
Murielle Fabre ◽  
Elvis Dohmatob ◽  
...  
Keyword(s):  
High Resolution ◽  
Brain Mapping ◽  
Cognitive Functions ◽  
Cognitive Mapping ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Cognitive Mechanisms ◽  
Precise Mapping ◽  
Objective Basis ◽  
High Level

Abstract Functional Magnetic Resonance Imaging (fMRI) has furthered brain mapping on perceptual, motor, as well as higher-level cognitive functions. However, to date, no data collection has systematically addressed the functional mapping of cognitive mechanisms at a fine spatial scale. The Individual Brain Charting (IBC) project stands for a high-resolution multi-task fMRI dataset that intends to provide the objective basis toward a comprehensive functional atlas of the human brain. The data refer to a cohort of 12 participants performing many different tasks. The large amount of task-fMRI data on the same subjects yields a precise mapping of the underlying functions, free from both inter-subject and inter-site variability. The present article gives a detailed description of the first release of the IBC dataset. It comprises a dozen of tasks, addressing both low- and high- level cognitive functions. This openly available dataset is thus intended to become a reference for cognitive brain mapping.

Functional Magnetic Resonance Imaging Evidence for a Hierarchical Organization of the Prefrontal Cortex

2007 ◽  
Vol 19 (12) ◽  
pp. 2082-2099 ◽  
Author(s):  
David Badre ◽  
Mark D'Esposito
Keyword(s):  
Magnetic Resonance Imaging ◽  
Prefrontal Cortex ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Hierarchical Organization ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Magnetic Resonance Imaging Evidence ◽  
Organized Action ◽  
Selection Of

The prefrontal cortex (PFC) is central to flexible and organized action. Recent theoretical and empirical results suggest that the rostro-caudal axis of the frontal lobes may reflect a hierarchical organization of control. Here, we test whether the rostro-caudal axis of the PFC is organized hierarchically, based on the level of abstraction at which multiple representations compete to guide selection of action. Four functional magnetic resonance imaging (fMRI) experiments parametrically manipulated the set of task-relevant (a) responses, (b) features, (c) dimensions, and (d) overlapping cue-to-dimension mappings. A systematic posterior to anterior gradient was evident within the PFC depending on the manipulated level of representation. Furthermore, across four fMRI experiments, activation in PFC subregions was consistent with the sub- and superordinate relationships that define an abstract representational hierarchy. In addition to providing further support for a representational hierarchy account of the rostro-caudal gradient in the PFC, these data provide important empirical constraints on current theorizing about control hierarchies and the PFC.

Voluntary Selection of Task Sets Revealed by Functional Magnetic Resonance Imaging

2006 ◽  
Vol 18 (3) ◽  
pp. 388-398 ◽  
Author(s):  
Birte U. Forstmann ◽  
Marcel Brass ◽  
Iring Koch ◽  
D. Yves von Cramon
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Everyday Life ◽  
Posterior Part ◽  
Choice Condition ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Task Set ◽  
Selection Of

In everyday life, we have to selectively adapt our behavior to different situations and tasks. In cognitive psychology, such adaptive behavior can be investigated with the task-switching paradigm. However, in contrast to everyday life, in experiments participants are unequivocally told which task to perform. The present functional magnetic resonance imaging (fMRI) study was set out to investigate processes that are relevant when participants can decide by their own which task to perform. The number of tasks to choose from was varied between a forced condition (no choice) and two voluntary selection conditions (two or three choices). We expected to find prolonged reaction times as well as higher activations within the midcingulate cortex for the choice conditions compared to the no-choice condition. The fMRI results revealed a significant activation difference for the choice conditions versus the no-choice condition. For the choice contrast, activation was found in the rostral cingulate zone (RCZ) as well as the superior parietal lobule and the posterior part of the intraparietal sulcus. These activations revealed no selection-specific difference between three and two choices. Finally, a post hoc analysis showed that the activation in the RCZ is not associated with higher task-dependent response conflict when participants can select a task set. Taken together, these findings indicate that distinct brain areas are involved in the voluntary selection of abstract task set information.

Preoperative evaluation by functional magnetic resonance imaging in patients with dysembryoplastic neuroepithelial tumours: A case series

2020 ◽  
Vol 31 (4) ◽  
pp. 158-164
Author(s):  
Natalia García-Casares ◽  
Francisco Alfaro-Rubio ◽  
José Ramón Ramos-Rodríguez ◽  
Álvaro Ocaña-Ledesma ◽  
Bernarda Márquez-Márquez ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Preoperative Evaluation ◽  
Case Series ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Neuroepithelial Tumours
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